154 results match your criteria: "Abant Izzet Baysal University Faculty of Medicine[Affiliation]"

Background: Triple rule-out computed tomography angiography (CTA) provides imaging of the coronary arteries, pulmonary arteries, and thoracic aorta filled with contrast material (CM) to exclude or diagnose the pathologies of these three systems. Although dual rule-out adapted to exclude aortic and pulmonary pathologies. Iodinated CM may result in contrast-induced nephropathy, which lengthens hospital stay.

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Background and objective Over the past decade, the use of psychostimulants typically prescribed for attention-deficit/hyperactivity disorder (ADHD), such as methylphenidate (MP), has become popular among undergraduate students to enhance their academic performance. Despite potential health and legal repercussions, the misuse of these medications has become a significant public health issue, not only in the general population but particularly among students in medical schools across Turkey. This study investigated the prevalence of MP misuse among Turkish medical students and the factors contributing to it.

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Article Synopsis
  • This study examined how taking breaks from the ADHD medication methylphenidate (MPH) during summer vacations affects ADHD symptoms and emotion regulation (ER) in children.
  • Fifty-six children participated, with evaluations happening before treatment, after treatment, and after the drug holidays. Out of those, 39 had complete data for analysis.
  • Results showed that while MPH treatment significantly reduced irritability and improved emotion recognition skills, these positive effects diminished after drug holidays, indicating the medication's benefits may be temporary.
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Background: Hand hygiene is a critical preventive measure for controlling infections, particularly in underdeveloped nations.

Materials And Methods: A cross-sectional study was conducted in a hospital in Mogadishu, Somalia, from January to March 2024. This study aimed to assess compliance with hand hygiene practices and related factors among healthcare professionals.

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  • Ocrelizumab (OCR) shows effectiveness in treating multiple sclerosis (MS) but can lead to a "wearing-off phenomenon" (WoP) prior to infusions.
  • A study involving 409 MS patients found that a substantial number experienced WoP symptoms, with many reporting issues like fatigue and walking difficulties four weeks before their next dose.
  • Factors such as shorter disease duration and longer intervals between doses were associated with increased WoP occurrence, indicating a need for more personalized treatment approaches.
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Noninvasive evaluation of significant liver fibrosis in chronic hepatitis B patients.

Acta Gastroenterol Belg

October 2024

Department of Infectious Diseases and Clinical Microbiology, Abant Izzet Baysal University Faculty of Medicine, Bolu, Turkey.

Background & Aims: Chronic hepatitis B is still a major cause of morbidity and mortality worldwide. In recent years, there has been increasing research on inexpensive, noninvasive, reproducible methods for detecting fibrosis in the liver. In this study, we examined the efficacy of 15 different noninvasive fibrosis markers for predicting significant liver fibrosis in chronic hepatitis B patients.

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Objectives: Coronary microvascular dysfunction is present in large percentage of the population, and it has been shown to have a pathological and prognostic role in many conditions. Therefore, early detection of microvascular dysfunction is important, especially in selected populations. The aim of this study was to investigate the association of galanin with coronary flow reserve (CFR) in prehypertensive individuals to determine whether it can be used as a marker to detect microvascular dysfunction.

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Introduction: Serious outbreaks of Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) have been reported globally. In 2011, Germany experienced a significant outbreak of HUS caused by enteroaggregative E. coli (EAEC) O104:H4 strain.

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Introduction: To investigate the presence of dysbiosis in patients with naive bladder cancer.

Methods: Twelve male patients with non-invasive bladder cancer and twelve age-matched healthy males had midstream urine and tissue samples taken. A history of endourological interventions was determined as an exclusion criterion, ensuring that the study was designed solely with naïve participants.

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Background: Obesity and type 2 diabetes mellitus are closely associated with each other and require careful management. This study aimed to assess the impact of sodium-glucose co-transporter 2 (SGLT2) inhibitors on glycemic control and body composition in diabetic patients, stratified by obesity status.

Methods: We enrolled patients diagnosed with type 2 diabetes mellitus, categorized as obese (BMI≥30) or non-obese (BMI<30), from our outpatient clinic.

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  • This study focuses on 17α Hydroxylase/17,20 Lyase Deficiency (17OHD), a rare form of adrenal hyperplasia, highlighting its clinical features such as delayed puberty and hypertension commonly diagnosed in late adolescence.
  • Researchers analyzed data from 97 cases across the country, revealing that hypertension was present in 65% and hypokalemia in 34% of patients, with a significant number requiring antihypertensive treatment.
  • The findings suggest that early diagnosis can be guided by hypertension and hypokalemia, while the final heights of patients generally fall within normal ranges, though the connection between genetic mutations and clinical outcomes remains unclear.
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  • This study aimed to compare childhood-onset schizophrenia (COS) and early-onset schizophrenia (EOS) in terms of clinical characteristics, treatment approaches, and factors influencing prognosis.
  • It involved analyzing data from 31 COS and 66 EOS patients, assessing their symptoms and treatment effectiveness using established scales during both acute and stable phases.
  • Significant differences were found in treatment outcomes and symptom severity between the two groups, with COS patients showing higher comorbidities and requiring more complex treatments, highlighting the need for early diagnosis and specific predictors for better management of schizophrenia.
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Background: This study investigates the gap in understanding the dynamics of recurring disease activity (RDA) in RRMS patients after fingolimod (FGL) treatment discontinuation. The aim is to investigate RDA in RRMS patients after stopping FGL, aiming to improve management and comprehension of disease progression post-treatment.

Methods: In this multicenter, retrospective study, data from 172 of 944 RRMS patients aged 18-55, across nine centers in Turkey, who discontinued FGL treatment, were analyzed.

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Background Objectives: Lyme disease is a multisystemic disease caused by the bacteria in the Borrelia burgdorferi sensu lato complex, which is transmitted by ticks of the Ixodes genus. Although there are seroprevalence studies and case reports of Lyme disease from various regions in Turkey, there is no widespread epidemiological research. This study aimed to determine the frequency of Lyme disease in the cases followed-up after tick contact and to examine the isolated ticks to reveal tick population from Bolu province.

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Pain types and risk factors in post-COVID-19.

Turk J Phys Med Rehabil

March 2024

Department of Physical Medicine and Rehabilitation, Güven Hospital, Ankara, Türkiye.

Objectives: This study aims to accurately evaluate pain lasting longer than three months and falls under the category of chronic pain and to determine the risk factors to follow up and treat properly and to develop appropriate diagnostic and treatment algorithms.

Patients And Methods: Between March 2021 and December 2021, a total of 437 patients (162 males, 275 females; mean age: 44±14.6 years; range, 12 to 82 years) who were referred to the participating centers due to pain complaints and were diagnosed with post-COVID-19 condition according to the criteria defined by the World Health Organization (WHO) were included in the study.

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Hypertension is a common public health issue, and its incidene increases parallel to age. It is inevitable that certain occupational conditions may pose risks for high blood pressure or cause difficulties in managing blood pressure. Working under specific circumstances may compromise the safety of individuals with hypertension and potentially others.

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Purpose: Our study aimed to obtain clinical indication-based typical dose values and size-specific dose estimates (SSDEs) for multiphasic abdominopelvic computed tomography (CT) examinations and to review our data with published diagnostic reference levels (DRLs).

Methods: In this retrospective study, multiphasic liver, kidney, pancreas, and mesenteric ischemia protocol CT scans performed at our center between January 2018 and December 2021 were analyzed. The clinical indications were hepatocellular carcinoma, renal cell carcinoma, pancreas adenocarcinoma, and mesenteric ischemia.

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Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders and is characterized by developmentally inappropriate, pervasive, and impairing symptoms of inattention and/or hyperactivity/impulsivity. Although not listed among the core symptoms, irritability, reduced tolerance to frustration, and labile mood are considered features associated with ADHD. Irritability refers to a tendency to get angry quickly and/or easily at a lower threshold of frustration and respond disproportionately to triggers.

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Purpose: While computed tomography pulmonary angiography plays an effective role in the diagnosis and prognosis of pulmonary embolism (PE), there are not enough studies regarding ventilation/perfusion (V/Q) scintigraphy. We aimed to evaluate the clinical outcomes of PE patients whose V/Q scintigraphy was reported as high probability for PE.

Method: Demographic data, Simplified Pulmonary Embolism Severity Index (SPESI), radiological findings, V/Q scintigraphy and echocardiographic (ECHO) findings, laboratory data, treatment information and comorbidities of 43 patients whose V/Q scintigraphy was reported as high probability for PE between January 2020 and January 2023 was recorded.

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