Prediction of Lymph Node Metastasis in Colon Cancer via Platelet to Lymphocyte Ratio and Platelet Count.

Objective: To investigate the value of preoperative blood tests in predicting lymph node metastasis in colon cancer patients undergoing surgery.

Study Design: Obervational study.

Place And Duration Of Study: General Surgery Department, Bolu Abant Izzet Baysal University Medicine School, Turkey, between December 2012 and December 2018.

Is Neuregulin-4 a predictive marker of microvascular complications in type 2 diabetes mellitus?

Background And Aims: Neuregulin-4 (Nrg-4) is a new adipokine released from brown adipose tissue. It plays pivotal role in regulating systemic energy balance, glucose and lipid metabolism and in reducing chronic inflammation. We aimed to investigate the relation between diabetic microvascular complications (DMC) and serum (Nrg-4) levels in patients with type 2 diabetes mellitus.

The relationship between tumor budding and survival in colorectal carcinomas.

Objective: Tumor budding is a parameter that is increasingly understood in colorectal carcinomas. We aimed to investigate the relationship between tumor budding, prognostic factors, and survival.

Methods: A total of 185 patients who had undergone colorectal surgery were observed.

MEAN PLATELET VOLUME: AN OVERLOOKED HERALD OF MALIGNANT THYROID NODULES.

Physicians and surgeons pay much attention to evaluating thyroid nodules due to the malignant potential of these growths. Inflammation has a crucial role in the development of cancer. Increase in the mean platelet volume (MPV) has been described in various inflammatory conditions.

Association between fragmented QRS complexes and left-ventricular dysfunction in anabolic androgenic steroid users.

Anabolic androgen steroid (AS) use has adverse effects on left ventricular functions, such as fibrosis development. Fragmented QRS is an important marker of myocardial fibrosis, while speckle-tracking echocardiographyis a method used to show subclinical left ventricle dysfunction. In this study, we examined the the ability of fQRS + to detect left ventricle fibrosis by speckle tracking echocardiography (STE) in AS users.

Neuregulin-4 is associated with plasma glucose and increased risk of type 2 diabetes mellitus.

Background: Neuregulin-4 is a cytokine with many functions and is primarily produced by fat tissue.

Aim Of The Study: The aim of the study was to observe the relationship between serum neuregulin-4 levels and diabetes regulation in type 2 diabetes mellitus (T2DM), and to compare neuregulin-4 levels of diabetic subjects with those in healthy controls.

Methods: Patients with T2DM were included to the study.

Is Uric Acid elevation a random finding or a causative agent of diabetic nephropathy?

Objective: In this study, we aimed to analyze the relationship between serum uric acid (UA) and microalbuminuria as a marker of renal injury in type 2 diabetes mellitus.

Methods: A total of 100 patients with type 2 diabetes mellitus were enrolled in the study. Participants were divided into two groups according to the urinary microalbumin/creatinine ratio: diabetic nephropathy and non-nephropathy group.

Uric acid to HDL cholesterol ratio is a strong predictor of diabetic control in men with type 2 diabetes mellitus.

Aim: Despite it has some disadvantages, the most important marker of diabetic control is glycated hemoglobin (HbA1c). Uric acid to HDL cholesterol ratio (UHR) is a promising marker in metabolic syndrome. We aimed to compare UHR levels of well and poorly controlled type 2 diabetic male subjects, as well as healthy men, and to observe its correlation with other metabolic parameters.

Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula?

Background: Coronary artery fistula (CAF) is an abnormal connection that links a coronary artery to a cardiac chamber or another major blood vessel. Several studies have shown the association between mean platelet volume (MPV) and cardiovascular diseases. In the literature, there is no previous study about the association between hematologic parameters and congenital CAF.

Association between novel inflammatory markers derived from hemogram indices and metabolic parameters in type 2 diabetic men.

Aim: Hemogram indices were proposed as novel inflammatory markers in chronic conditions and inflammation has substantial role in the pathogenesis of type 2 diabetes mellitus (T2DM). We aimed to observe hemogram parameters of type 2 diabetic male subjects with various age groups in well and poorly controlled subsets.

Methods: Data of type 2 diabetic men enrolled to the study were recorded from patient files of the institution.

Type 2 diabetes mellitus is more commonly well controlled in younger men compared to older men.

Methods: The male patients with T2DM that admitted to the outpatient internal medicine clinics of our institution between November 2018 and April 2019 were included to the study. According to the age, study population divided into two groups; either younger than 60 years (group I) and 60 years or older (group II). Study parameters were compared between study groups.

Neutrophil to lymphocyte ratio as an indicative of diabetic control level in type 2 diabetes mellitus.

Background: Type 2 diabetes mellitus is associated with chronic low grade inflammation. One of the novel inflammatory markers is hemogram derived neutrophil to lymphocyte ratio (NLR).

Objective: We aimed to compare NLR levels of diabetic subjects and healthy controls and to observe possible correlation between NLR and HbA1c.

General characteristics of anemia in postmenopausal women and elderly men.

In present study, we aimed to investigate anemia etiologies, underlying causes, laboratory markers of anemia, required interventions in postmenopausal women and elderly men. The medical data of the anemic subjects were recorded from the patients' files and computerized database of the institution and retrospectively analyzed. Study population grouped into two according to the gender; men and women.

Detection Rate of Thyroid Papillary Micro-carcinoma in Multinodular Goiter Surgery.

Objective: To determine the frequency of papillary thyroid micro-carcinoma (PTMC) in multinodular goiter (MNG) surgery, as well as in opposite thyroid lobule of the dominant nodule.

Study Design: Descriptive study.

Place And Duration Of Study: General Surgery Department, Abant Izzet Baysal University Hospital, between January 2010 and December 2016.

Neutrophil to Lymphocyte Ratio is Useful in Differentiation of Malign and Benign Thyroid Nodules.

Objective: Significant amount of thyroid nodules are malignant. Inflammation plays crucial role in the pathogenesis of many disorders, including cancer. Neutrophil to lymphocyte ratio (NLR), has been suggested as an index of inflammatory response and association between increased NLR and cancer has also been reported.

Diabetic regulation of subjects with type 2 diabetes mellitus is associated with serum vitamin D levels.

Objective: Vitamin D deficiency is not only associated with bone metabolism but also with diabetes mellitus. We aimed to study the possible association between serum vitamin D concentration and HbA1c level in patients with type 2 diabetes mellitus (T2DM) in this retrospective report.

Methods: Patients with T2DM were enrolled to the study either in regulated or non-regulated T2DM groups, according to HbA1c levels.

Diabetes control could through platelet-to-lymphocyte ratio in hemograms.

Objective: Association between type 2 diabetes mellitus and inflammation is well-established. We aimed to study platelet-to-lymphocyte ratio (PLR), a novel inflammatory index derived from hemogram, in diabetic patients in comparison to those in healthy volunteers.

Methods: Medical data of type 2 diabetics that showed up in general outpatient medical clinics of our institution between February 2017 and August 2017 were recorded and analyzed.

Association of mean platelet volume and red blood cell distribution width with coronary collateral development in stable coronary artery disease.

Introduction: The prognostic value of hematological indices in cardiovascular diseases and the association between these parameters and cardiovascular conditions have been established in the literature.

Aim: In this study, we aimed to investigate the relation of mean platelet volume (MPV), MPV to platelet ratio (MPR) and red cell distribution width (RDW) with degree of coronary collateral development (CCD) in stable coronary artery disease (CAD) subjects with established critical coronary artery stenosis.

Material And Methods: A total of 306 patients with stable angina pectoris undergoing coronary arteriography were enrolled and divided on the basis of the development of CCD into two groups: a group with adequate CCD ( = 214) and a group with impaired CCD ( = 92).

Analysis of the Factors Related to the Blood Pressure Control in Hypertension.

Objective: To determine the factors associated with blood pressure control and comparing anthropometric and clinical parameters of subjects with well-controlled hypertension to those with poorly controlled blood pressure.

Study Design: Observational cross-sectional study.

Place And Duration Of Study: Abant Izzet Baysal University Hospital, Bolu, Turkey, from January to June 2016.

Elevated neutrophil-to-lymphocyte ratio in the diagnosis of Hashimoto's thyroiditis.

Objective: Hashimoto's thyroiditis (HT) is an autoimmune inflammatory disorder. The purpose of this study was to determine the neutrophil-to-lymphocyte ratio (NLR), a novel marker of inflammation, in patients with HT and to compare these values with those from healthy subjects.

Method: A total of 154 participants were included in the study, 90 HT patients and 64 healthy volunteers.

Novel Mortality Markers for Critically Ill Patients.

Aim: Inflammatory markers, such as the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), derived from a complete blood count have recently attracted attention as potential markers of morbidity and mortality in various diseases. The aim of the present study was to assess the usefulness of the NLR and PLR as markers of hospital stay and mortality of patients in intensive care units (ICUs).

Methods: Patients treated in the ICU of our institution between October 2016 and August 2017 were enrolled in the study.

Could Red Cell Distribution Width be a Marker of Thyroid Cancer?

Objective: To study red cell distribution width (RDW) values, a novel inflammatory marker in routine hemogram, of patients with benign or malignant thyroid nodules and to compare with healthy population.

Study Design: Descriptive study.

Place And Duration Of Study: Abant Izzet Baysal University Hospital, Bolu, Turkey, from November 2015 and February 2017.

Association Between Hemogram Parameters and Survival of Critically Ill Patients.

Aim: Recently, hemogram parameters, such as mean platelet volume (MPV), had been proposed as novel inflammatory and prognostic factors. In present retrospective analysis, we aimed to determine and compare MPV of survived and dead patients whom admitted to intensive care unit (ICU) of our institution.

Methods: We recorded hemogram parameters and other laboratory data and demographic characteristics of patients treated in ICU.

Could red cell distribution width and mean platelet volume be a predictor for lumbar disc hernias?

Background And Purpose: Lumbar disc herniation (LDH) causes major disabilities worldwide. Several studies in the literature had reported the correlation between radiculopathy and inflammatory markers. Mean platelet volume (MPV), red cell distribution width (RDW) and neutrophil to lymphocyte (N/L) ratio are parameters of hemogram which have been found to be associated with inflammatory conditions.

Evaluation of simple blood counts as inflammation markers for brain tumor patients.

Aims: Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate inflammatory markers in brain tumor patients. We aimed to observe RDW and MPV values of tumor patients and compare to those in healthy population.