Give it time to SOBER up - GITSU- a new strategy in percutaneous coronary intervention for chronic total occlusion.

Background: The prevalence of coronary chronic total occlusion (CTO) in coronary angiography (CAG) has risen with ageing populations, along with the expansion of CTO percutaneous coronary interventions (CTO-PCI). However, CTO-PCI encounters challenges such as undersized stents, dissection risks, and limited access to intravascular imaging (IVI), particularly in regions with limited health budgets. This study introduces the 'GIVE IT TIME TO SOBER UP - GITSU strategy', a two-session CTO-PCI approach where Thrombolysis in Myocardial Infarction (TIMI-3) antegrade flow is achieved without stent placement in the first session.

The SPICE Modeling of a Radiation Sensor Based on a MOSFET with a Dielectric HfO/SiO Double-Layer.

We report on a procedure for extracting the SPICE model parameters of a RADFET sensor with a dielectric HfO/SiO double-layer. RADFETs, traditionally fabricated as PMOS transistors with SiO, are enhanced by incorporating high-k dielectric materials such as HfO to reduce oxide thickness in modern radiation sensors. The fabrication steps of the sensor are outlined, and model parameters, including the threshold voltage and transconductance, are extracted based on experimental data.

The Effect of Frailty on Balance, Fear of Falling, and Dual-Task Performance in Individuals with Type 2 DM.

The aim of this study was to compare balance, fear of falling, and dual-task performance in frail, pre-frail, and non-frail individuals with type 2 DM. The study included 110 voluntary individuals diagnosed with type 2 DM. Individuals with type 2 DM were divided into three groups according to the FRAIL Scale: frail ( = 26), pre-frail ( = 52), and non-frail ( = 32).

Overcoming low status or maintaining high status? A multinational examination of the association between socioeconomic status and honour.

We examined the relationship between socioeconomic status (SES) and endorsement of honour. We studied the SES-honour link in 5 studies (N = 13,635) with participants recruited in different world regions (the Mediterranean and MENA, East Asian, South-East Asian, and Anglo-Western regions) using measures that tap into various different facets of honour. Findings from these studies revealed that individuals who subjectively perceived themselves as belonging to a higher (vs.

Evaluation of Information Provided by ChatGPT Versions on Traumatic Dental Injuries for Dental Students and Professionals.

Background/aim: The use of AI-driven chatbots for accessing medical information is increasingly popular among educators and students. This study aims to assess two different ChatGPT models-ChatGPT 3.5 and ChatGPT 4.

First Record and Identification of a Microsporidian Pathogen, Nosema Maddoxi in the Population of Brown Marmorated Stink Bug Halyomorpha Halys (Hemiptera: Pentatomidae) in Türkiye.

Purpose: The brown marmorated stink bug, Halyomorpha halys (Hemiptera: Pentatomidae), is an invasive and a highly polyphagous species with a strong dispersal capacity. Unfortunately, there is currently no effective control method that can prevent or reduce the economic loss caused by this pest. Among natural enemies, microsporidia cause infections in insects so that they can generally shorten life span, reduce fertility and inhibit growth.

Comparison of the effect of different irrigation activation systems on the amount of apical extrusion of irrigation solution in teeth with severely curved canals.

Objective: This study aims to quantitatively compare the effects of standard needle irrigation (SNI), passive ultrasonic irrigation (PUI), EDDY, photon-initiated photoacoustic streaming (PIPS), and shock wave-enhanced emission photoacoustic streaming (SWEEPS) on the apical extrusion of irrigation solutions in teeth with severe canal curvature.

Materials And Methods: Seventy-five teeth with a single root and canal, and curvature angles ranging from 20° to 40°, were selected for this study. Root canal curvatures were measured from buccolingual and mesiodistal radiographs using ImageJ software (version 1.

Effects of HDAC Activity in Hydroxychloroquine-Applied Human Primary Chondrocyte and Nucleus Pulposus Cultures.

Aim: This study was conducted to evaluate the in vitro effects of hydroxychloroquine (HCQ) on histone deacetylase (HDAC) enzyme activity and interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha (TNF-α) expression. HDAC enzyme activity and the expression of inflammation markers were tested, with the presence of the HDAC inhibitor valproic acid, in human primary cell cultures prepared from two different tissues.

Material And Methods: Primary cell cultures were prepared.

Gold Nanoparticle-Modified Molecularly Imprinted Polymer-Coated Pencil Graphite Electrodes for Electrochemical Detection of Bisphenol A.

The sensitive Bisphenol A (BPA) detection by an electrochemical sensor based on gold nanoparticle-doped molecularly imprinted polymer was successfully improved. This study describes the development of a method for BPA detection in both aqueous solution and real water samples using N-methacroyl-(L)-cysteine methyl ester and N-methacryloyl-(L)-phenylalanine methyl ester coated pencil graphite electrodes modified with AuNPs by differential pulse voltammetry (DPV). Importantly, AuNPs, which increase the electroactivity, were used to increase the surface area of a BPA-imprinted pencil graphite electrode (MIP PGE) sensor.

Editorial: The Effects of COVID-19 on Adolescent Well-Being and Psychopathology in a Multinational, Multicountry Sample Within the First Two Years of the Pandemic Provide Further Clues for Mental Health Disparities.

Throughout history, epidemics of infections and the response of human societies to contain them expose and interact with disparities in health, economic, political, environmental and societal systems. Works of literature such as the play Romeo and Juliet by William Shakespeare serve as witnesses to these interactions. The COVID-19 pandemic was the biggest recent global public health crisis, and its toll had surpassed 7 million deaths worldwide as of late December 2024, among which 1.

Identification and management of Bipolaris sorokiniana in wheat and barley in Southeast Kazakhstan.

Wheat and barley serve as significant nutrient-rich staples that are extensively grown on a global scale, spanning over 219 million hectares. The annual combined global yield is 760.9 million tons, with Kazakhstan contributing 14.

The Effect of Clinical Observations on Nursing Students' Compliance with Standard Precautions: A Cross-sectional Study.

Background: Healthcare-associated infections pose a significant global challenge, highlighting the need for enhanced knowledge and practices among healthcare professionals. This study investigates the impact of clinical observations on nursing students' compliance with standard precautions.

Methods: Employing a cross-sectional descriptive design, the study surveyed 405 nursing students using a 'Personal Information Form', the 'Nurses' Observations on Infection Control and Prevention Questionnaire', the 'Standard Precautions Scale', and the 'Factors Affecting Compliance with Standard Precautions Scale'.

CXCL13 levels in cerebrospinal fluid in relapsing-remitting multiple sclerosis: The role of Borrelia in neuroinfections.

Background Objectives: This study was compared the Borrelia antibodies and chemokine ligand 13 (CXCL13) levels in cerebrospinal fluid (CSF) samples from cases diagnosed with relapsing-remitting multiple sclerosis (RRMS), radiologically isolated syndrome (RIS), and pseudotumour cerebri (PTC).

Methods: A total of 43 CSF samples were collected from patients diagnosed with RRMS, RIS and PTC. We prospectively investigated Borrelia IgG and IgM antibodies in the CSF samples of the cases by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) method, and CXCL13 levels by ELISA.

The effect of carvacrol on reducing bacterial translocation, liver and intestinal damage in obstructive jaundice models of rats.

BACKGROUND Obstructive jaundice is a common surgical issue caused by obstruction in the bile ducts, which can result from factors such as stones or cancers in the main bile duct. This study aimed to investigate the effects of carvacrol, a compound known for its strong antioxidant properties, on intestinal damage, liver damage, and bacterial translocation in an animal model of obstructive jaundice. METHODS The study utilized six groups of six Wistar Albino rats each.

The effect of different beverages on the surface characteristics of PEEK and PEKK polymers.

Purpose: To evaluate the effects of various beverages on surface roughness and microhardness of PEEK and PEKK polymers.

Methods: Rectangular-shaped PEEK and PEKK polymers were fabricated and examined in the study. The specimens were immersed for 28 days at 37°C in red wine, coffee, and distilled water.

The Moderating Role of Gender and Mediating Role of Hope in the Performance of Healthcare Workers During the COVID-19 Pandemic.

This study aimed to examine the relationship between resilience and the hope levels of healthcare workers who have experienced the COVID-19 pandemic, the effects of resilience and gender on individual performance, the effects of hope levels on individual performance, and aimed to determine whether hope mediated the effect of resilience on individual performance. This was a descriptive cross-sectional study. The psychological resilience, hope, and individual performance of healthcare workers affiliated with the Istanbul Provincial Health Directorate were obtained from online questionnaires completed by participants between April 2021 and August 2021.

Impact of Neutrophil-to-Lymphocyte Ratio on Stroke Severity and Clinical Outcome in Anterior Circulation Large Vessel Occlusion Stroke.

The prognostic value of the neutrophil-lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates the relationship between admission NLR, stroke severity and 90-day outcomes in patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. A retrospective multicenter study was conducted with 1082 patients treated with mechanical thrombectomy for acute ischemic stroke.

Childbirth Journey Through Virtual Reality: Pain, Anxiety and Birth Perception: A Randomized Controlled Trial.

This study determines video's effect on pregnant women's pain, anxiety, and perception of labor using virtual reality glasses during the active and transition phases of childbirth. This randomized controlled study was conducted with 60 pregnant women (30 in each group) admitted to the delivery room of a hospital. The data were collected by personal information form, visual comparison scale-pain, visual comparison scale-anxiety, and perception of birth scale.

Broccoli () leaves exhibit significant antidiabetic potential in alloxan-induced diabetic rats: the putative role of ABC vacuolar transporter for accumulation of Quercetin and Kaempferol.

Background: The global prevalence of diabetes among adults over 18 years of age is expected to increase from 10.5% to 12.2% (between 2021 and 2045).

Translucency and contrast ratio of dimetharcyrlate resin based dental materials after bleaching: an in-vitro study.

Objective: To compare the translucency and contrast ratio of 13 different resin based restorative materials and to evaluate the effect of 2 different bleaching methods on the translucency and contrast ratio of these materials.

Methods: In this study, a total of 260 samples were prepared, 20 from each of 13 different dimethacrylate-based restorative materials. Then, each material group was divided into 4 subgroups.

The use of dual and triple rule-out computerized tomography angiography by using diagnostic low-dose contrast material and radiation in acute chest pain.

Background: Triple rule-out computed tomography angiography (CTA) provides imaging of the coronary arteries, pulmonary arteries, and thoracic aorta filled with contrast material (CM) to exclude or diagnose the pathologies of these three systems. Although dual rule-out adapted to exclude aortic and pulmonary pathologies. Iodinated CM may result in contrast-induced nephropathy, which lengthens hospital stay.

Effects of cold-pressed oil additives in varying proportions: Physico-chemical characteristics of mayonnaises.

This study evaluated the effects of incorporating cold-pressed sesame (C-SEO), safflower (C-SAO), and black cumin oils (C-BCO) into mayonnaise at substitution ratios of 0-20 % to sunflower oil. Refined sunflower oil had the lowest free fatty acids (FFA) and strong antiradical activity due to high α-tocopherol and β-carotene content. C-BCO showed the highest oxidation levels with a peroxide value of 6.

THE RELATIONS BETWEEN THYROID HORMONES AND CLINICAL FEATURES OF TURKISH CHILDREN AND ADOLESCENTS WITH ADHD AND ADHD-NOS: A PRELIMINARY STUDY.

The aim of this study was to compare the levels of thyroid hormones in children with ADHD and ADHD-NOS and to assess the relationship between ADHD symptom severity, anxiety symptom severity and thyroid hormone levels. The study was planned as a cross-sectional, retrospective study. The records of patients who applied to the study center in between January 2012 and January 2013 were screened and 205 ADHD and ADHD-NOS cases' records were evaluated.

Examining the relationship between language development, executive function, and screen time: A systematic review.

This systematic review study examines the relationship between language development, executive function, and screen time in early childhood. The early childhood period is a crucial phase for the development of the brain, during which fundamental language and executive function skills undergo rapid evolution. This review synthesizes findings from 14 peer-reviewed studies that focused on language development, executive function, and screen time together to provide a comprehensive understanding of their relationship.