4 results match your criteria: "Aarhus University Hospital Skejby - Psychiatry[Affiliation]"
Brain Activation and Aberrant Effective Connectivity in the Mentalizing Network of Preadolescent Children at Familial High Risk of Schizophrenia or Bipolar Disorder.
Biol Psychiatry Cogn Neurosci Neuroimaging
January 2025
Center of Functionally Integrative Neuroscience, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address:
Background: Schizophrenia and bipolar disorder are characterized by social cognitive impairments, and recent research has identified alterations of the social brain. However, it is unknown whether familial high risk (FHR) of these disorders is associated with neurobiological alterations already present in childhood.
Methods: As part of the Danish High Risk and Resilience Study-VIA 11, we examined children at FHR of schizophrenia (n = 121, 50% female) or bipolar disorder (n = 75, 47% female) and population-based control children (PBCs) (n = 128, 48% female).
Social responsiveness in families with parental schizophrenia or bipolar disorder-The Danish High Risk and Resilience Study.
Psychiatry Res
May 2023
Department of Clinical Medicine, Faculty of Health and Medical Sciences, Aarhus University, Aarhus, Denmark; The Psychosis Research Unit, Aarhus University Hospital Skejby - Psychiatry, Aarhus, Denmark; iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Asrhus, Denmark.
Schizophrenia and bipolar disorder are highly heritable severe mental disorders associated with social impairments. Moreover, partners to individuals with one of these disorders display poorer functioning and more psychopathology, but their social skills and the transgenerational transmission remains uninvestigated. Therefore, we aimed to examine social responsiveness in families with parental schizophrenia or bipolar disorder.
View Article and Find Full Text PDFDevelopment of social responsiveness and theory of mind in children of parents with schizophrenia or bipolar disorder.
Schizophr Res Cogn
June 2022
Department of Clinical Medicine, Faculty of Health and Medical Sciences, Aarhus University, Palle Juul-Jensens Boulevard 82, DK-8200 Aarhus N, Denmark.
Social impairments are suggested as vulnerability markers for schizophrenia and bipolar disorder. Therefore, we investigated the development of social responsiveness and theory of mind (ToM) in children at familial high-risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP). This study is part of The Danish High Risk and Resilience Study, a longitudinal cohort study of children at FHR-SZ or FHR-BP and population-based controls (PBC).
View Article and Find Full Text PDFExploring protective and risk factors in the home environment in high-risk families - results from the Danish High Risk and Resilience Study-VIA 7.
BMC Psychiatry
February 2022
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
Background: Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder.
Methods: From a cohort of 522 children, data from 463 7-year-old children was included.