The effect of mortality salience and early-life maternal care on neuroendocrine, autonomic, and psychological stress responses.

Adverse early-life experiences alter the regulation of major stress systems such as the hypothalamic-pituitary-adrenal (HPA) axis. Low early-life maternal care (MC) has repeatedly been related to blunted cortisol stress responses. Likewise, an acutely increased awareness of mortality (mortality salience [MS]) also has been shown to blunt cortisol responses.

Comparative evaluation of removal of oil-based calcium hydroxide intracanal medicaments with two calcium chelators: An cone-beam computed tomography volumetric analysis.

Background: Intracanal medicament (ICM) eliminates remaining bacteria and their toxins that were not removed by chemomechanical preparation during endodontic treatment.

Aim: The aim of this study was to compare and evaluate the removal of ozonated oil-based, silicone oil-based, and distilled water-based ICM with two calcium chelators, i.e.

The effects of compassionate care on oral health outcomes: A scoping review.

Purpose: To access and synthesize the existing literature about the effects of compassionate care on oral health outcomes.

Methods: A scoping review was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to identify articles from six electronic databases: MEDLINE via the PubMed interface, Embase, Age-Line, Scopus, CINAHL, and Cochrane.

Results: Among 30 studies reporting on compassion in dental treatment, only two reported on the effects of compassionate care on oral health outcomes.

Extended clinical phenotypes and treatment modalities in 32 JAGN1-deficient patients. A multicenter study by EBMT IEWP.

JAGN1 (Jagunal-homolog1) is a ER-resident transmembrane protein which is part of the early secretory pathway and granulocyte colony-stimulating factor receptor mediated signaling. Autosomal recessively inherited variants in the JAGN1 gene lead to congenital neutropenia, early-onset bacterial infections, aphthosis and skin abscesses due to aberrant differentiation and maturation of neutrophils. In addition, bone metabolism disorders and a syndromic phenotype, including facial features, short stature and neurodevelopmental delay, have been reported in affected patients.

EWSR1::BEND2 Adenocarcinoma with Hyaline Pseudorosettes of the Trachea.

We describe the novel occurrence of a adenocarcinoma involving the trachea, with distinct solid and glandular components, in a 34-year-old patient. We illustrate its morphological and immunophenotypic features and describe the molecular finding of an EWSR1::BEND2 gene fusion detected by next-generation sequencing (NGS). We discuss the findings in comparison to BEND2-fusion associated neoplasms reported in the head and neck region in the literature to date.

Surgical technique of minor revision of a transcutaneous osseointegration prosthetic system (TOPS) with implant retention.

Objective: Transcutaneous osseointegration prosthetic systems (TOPS) offer a stable skeletal attachment for artificial limbs post-extremity amputation, serving as an alternative to socket attachment. Press-fit osseointegration implants (OI) utilized in TOPS consistently enhance quality of life and mobility for amputees, particularly those experiencing socket-related issues. Despite notable benefits, late complications such as infection and implant loosening pose challenges unique to TOPS due to their percutaneous nature.

Examining associations between oral cancer mortality and economic development of 13 European countries: an ecological and correlational study.

Background: Cancer is a significant public health issue all over the world. The diagnosis, treatment and follow-up of cancer patients are a huge health, economic and social burden for societies. The link between the state of health of a country and its economic performance has been proven by numerous studies.

Bibliometrics and altmetrics on halitosis: exploring the top 100 most-cited papers.

Halitosis has a multifactorial etiology being of interest by different health areas. The aim of this study was to perform a bibliometric and altmetric analyzes of the top 100 most-cited papers on halitosis to provide a comprehensive view of their scientific and alternative metrics. This would give perspectives on citation dynamics and online attention of the research outputs.

Effect of quality of radiographs taken during root canal treatment on technical quality of root canal fillings and endodontic outcome.

Objectives: This study evaluated the number and quality of working length (WL) and master cone (MC) radiographs taken during root canal treatment by dental undergraduates, and their associations with the technical quality of root canal fillings (TQRCF) and endodontic outcomes (EO).

Methods: A retrospective evaluation of radiographs from 303 root canal-treated teeth in 231 patients was conducted, with 72 patients attending recall visits to assess EO. The chi-square and one-way analysis of variance tests were performed.

Susceptibility of Tambaqui () to Nile Tilapia-Derived and .

Nile tilapia () and tambaqui () are the two most produced freshwater fishes in Brazil. This study investigated the potential pathogenicity of and , previously isolated from diseased Nile tilapia, to tambaqui. Experimental infection trials were conducted in juvenile tambaqui at a dose of approximately 10 CFU fish, assessing clinical signs, mortality, bacterial recovery, and histopathological changes.

The Impact of Postoperative Albumin Levels on Furosemide Efficacy in Infants with Congenital Heart Disease.

Postoperative fluid overload is associated with increased mortality and morbidity in infants with congenital heart disease (CHD). Loop diuretics, such as furosemide, are commonly used to prevent fluid overload in the postoperative period. This study aimed to investigate the effect of postoperative albumin levels on the efficacy of furosemide after surgery in infants with CHD.

Efficacy of Novel Digital-Based Surgical Guide in the Limited Interocclusal Distance.

Accurate implant placement is essential for achieving successful outcomes. To aid in this, digitally designed surgical guides have been introduced. Both closed-sleeve and open-sleeve designs are commonly utilized.

Longer Duration of Cord Clamping Improves Nicu Survival Without Major Morbidities in Very Preterm Infants.

Background: Longer duration of deferred cord clamping (DCC), at least 120 s, is associated with the highest reduction in mortality compared to shorter durations of DCC or immediate cord clamping in preterm infants. We compared the neonatal outcomes of very preterm infants who received at least 60 s to those who received at least 120 s of DCC.

Methods: This is a retrospective single-center study including preterm infants born <33 weeks of gestational age (GA) between 2014 and 2019.

Dairy Cattle and the Iconic Autochthonous Cattle in Northern Portugal Are Reservoirs of Multidrug-Resistant .

Animals destined for human consumption play a key role in potentially transmitting bacteria carrying antibiotic resistance genes. However, there is limited knowledge about the carriage of antibiotic-resistant bacteria in native breeds. We aimed to characterize the phenotypic profiles and antibiotic resistance genes in isolated from bovines, including three native Portuguese bovine breeds.

Spermidine Enhances Mitochondrial Bioenergetics in Young and Aged Human-Induced Pluripotent Stem Cell-Derived Neurons.

The accumulation of damaged mitochondria has long been considered a hallmark of the aging process. Among various factors, age-related mitochondrial alterations comprise bioenergetic impairments and disturbances in reactive oxygen species (ROS) control, thereby negatively affecting mitochondrial performance and ultimately accelerating aging. Previous studies have revealed that polyamine spermidine appears to exert health-protective and lifespan-promoting effects.

Effects of Isoflavone Intake on Energy Requirement, Satiety, and Body Composition of Neutered Adult Cats.

Isoflavones are composed of phytoestrogens (genistein and daidzein), which can be metabolized by cats. These compounds can promote the maintenance of lean body mass and control food intake. These effects are desirable in neutered animals, as they are predisposed to obesity.

Impact of preoperative pes planus on orthopaedic implant removal following first metatarsophalangeal joint arthrodesis: A retrospective analysis.

First metatarsophalangeal (MTP) joint fusion is a frequently employed surgical treatment option for hallux rigidus and hallux valgus. Implant-related complications are common, necessitating further investigation into predisposing factors. The altered mechanics of pes planus may influence surgical outcomes; however, its direct impact on implant removal rates post-fusion remains unclear.

Executive Summary: Clinical Practice Guidelines on the Management of Resistant Tuberculosis of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).

The Spanish Society of Pneumology and Thoracic Surgery (SEPAR) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) have developed together Clinical Practice Guidelines (GPC) on the management of people affected by tuberculosis (TB) resistant to drugs with activity against Mycobacterium tuberculosis. These clinical practice guidelines include the latest updates of the SEPAR regulations for the diagnosis and treatment of drug-resistant TB from 2017 and 2020 as the starting point. The methodology included asking relevant clinical questions based on PICO methodology, a literature search focusing on each question, and a systematic and comprehensive evaluation of the evidence, with a summary of this evidence for each question.

Effect of exercise training on modulating the TH17/TREG imbalance in individuals with severe COPD: A randomized controlled trial.

Background: Chronic obstructive pulmonary disease (COPD) induces an imbalance in T helper (Th) 17/regulatory T (Treg) cells that contributes to of the dysregulation of inflammation. Exercise training can modulate the immune response in healthy subjects.

Objective: We aimed to evaluate the effects of exercise training on Th17/Treg responses and the differentiation of Treg phenotypes in individuals with COPD.

Fracture Resistance of Chairside CAD/CAM Lithium Disilicate Partial and Full Coverage Crowns and Veneers for Maxillary Canines.

Objective: This study aimed to assess the fracture resistance of chairside computer assisted design and computer assisted manufacturing (CAD-CAM) lithium disilicate partial and full-coverage crowns and veneers for maxillary canines.

Methods And Materials: Forty-eight restorations for maxillary right canines (12 per group) were designed as follows: (1) partial crown with finish line in the upper middle third; (2) partial crown with finish line in the lower middle third; (3) traditional labial veneer; and (4) traditional full-coverage crown. Restorations were fabricated out of lithium disilicate (Amber Mill, Hassbio) using a chairside CAD-CAM system (Cerec Dentsply Sirona).

Two FAM134B isoforms differentially regulate ER dynamics during myogenesis.

Endoplasmic reticulum (ER) plasticity and ER-phagy are intertwined processes essential for maintaining ER dynamics. We investigated the interplay between two isoforms of the ER-phagy receptor FAM134B in regulating ER remodeling in differentiating myoblasts. During myogenesis, the canonical FAM134B1 is degraded, while its isoform FAM134B2 is transcriptionally upregulated.

Predictive Factors of Dental Implant Failure: A Retrospective Study Using Decision Tree Regression.

Introduction: Dental implants are routinely used to replace missing teeth. Therefore, the primary aim of the present study was to assess the single-unit implant failure rate over a period of seven years from 2015 to 2021, with a minimum of two years post-implant follow-up. The secondary aim was to identify the risk factors associated with implant failure using machine learning decision tree regression and Kaplan-Meier survival analyses.