65 results match your criteria: "AORN Ospedali dei Colli-Monaldi Hospital[Affiliation]"
Infection
December 2024
Department of Precision Medicine, University of Campania 'L. Vanvitelli' Napoli, Naples, Italy.
Purpose: Infective endocarditis (IE) is a heterogeneous disease undergoing epidemiological changes. Whether those changes have an impact on the correlates of embolic events (EE) remains unclear. We analyzed the correlates of EE and proposed a diagnostic score model in a large contemporary cohort.
View Article and Find Full Text PDFHeart Rhythm
November 2024
Department of Precision Medicine, University of Campania L. Vanvitelli, Naples, Italy; Unit of Internal Medicine and Transplants, AORN Ospedali dei Colli-Monaldi Hospital, Naples, Italy. Electronic address:
Anaerobe
December 2024
Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127, Trieste, Italy. Electronic address:
Eur J Intern Med
October 2024
Department of Precision Medicine, University of Campania 'L. Vanvitelli', and Unit of Internal Medicine and Transplants, AORN Ospedali dei Colli-Monaldi Hospital, Naples, Italy. Electronic address:
Clin Transl Sci
July 2024
Department of Pharmacy, Uppsala University, Uppsala, Sweden.
The AIDA randomized clinical trial found no significant difference in clinical failure or survival between colistin monotherapy and colistin-meropenem combination therapy in carbapenem-resistant Gram-negative infections. The aim of this reverse translational study was to integrate all individual preclinical and clinical pharmacokinetic-pharmacodynamic (PKPD) data from the AIDA trial in a pharmacometric framework to explore whether individualized predictions of bacterial burden were associated with the trial outcomes. The compiled dataset included for each of the 207 patients was (i) information on the infecting Acinetobacter baumannii isolate (minimum inhibitory concentration, checkerboard assay data, and fitness in a murine model), (ii) colistin plasma concentrations and colistin and meropenem dosing history, and (iii) disease scores and demographics.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
May 2024
Microbiology and Virology Unit, Great Metropolitan Hospital "Bianchi-Melacrino-Morelli", Reggio Calabria, Italy.
World J Urol
January 2024
Department of Urology, "Hesperia Hospital", and CURE Group, Modena, Italy.
J Clin Med
December 2023
Department of Precision Medicine, University of Campania 'L. Vanvitelli', Via de Crecchio, 7, 80138 Napoli, Italy.
(1) Background: Leadless pacemakers (LPs) have been proposed as a reimplantation strategy in pacing-dependent patients undergoing cardiac implantable electronic device (CIED) extraction for infection. In this study, we analysed the risk of LP infection when this device is implanted before lead extraction. (2) Methods: This was a retrospective study including patients who underwent LP implantation between 2017 and 2022.
View Article and Find Full Text PDFEur Heart J Case Rep
December 2023
Cardiology Unit, Department of Translational Medical Sciences, University of Campania 'Luigi Vanvitelli', AORN Ospedali dei Colli Monaldi Hospital, Via L. Bianchi 1 c/o Monaldi Hospital, AORN Colli, Naples 80131, Italy.
Background: Interatrial block (IAB) is a conduction delay in Bachmann's bundle with a well-described association with structural heart disease, supraventricular arrhythmias, and cardiovascular events.
Case Summary: We report the case of an asymptomatic 35-year-old man in whom the presence of IAB at electrocardiogram led to a comprehensive evaluation including speckle-tracking echocardiography, 24 h Holter monitoring, and genetic testing. Speckle-tracking echocardiography demonstrated a decrease in the longitudinal strain of interventricular septum, a typical feature of LMNA-related cardiomyopathy, and decreased indices of left atrial deformation.
J Clin Med
September 2023
Department of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Disseminated intravascular coagulation (DIC) is a recurrent complication of sepsis. Since DIC not only promotes organ dysfunction but also represents a strong prognostic factor, it is important to diagnose DIC as early as possible. When coagulation is activated, fibrinolysis is inhibited, blood thinners are consumed, and a condition is created that promotes blood clotting, making it more difficult for the body to remove fibrin or prevent it from being deposited in the blood vessels.
View Article and Find Full Text PDFJ Antimicrob Chemother
November 2023
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Cells
August 2023
Department of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Sepsis is a major global health problem that results from a dysregulated and uncontrolled host response to infection, causing organ failure. Despite effective anti-infective therapy and supportive treatments, the mortality rate of sepsis remains high. Approximately 30-80% of patients with sepsis may develop disseminated intravascular coagulation (DIC), which can double the mortality rate.
View Article and Find Full Text PDFEur J Intern Med
October 2023
Unit of Infectious and Transplant Medicine, AORN Ospedali dei Colli-Monaldi Hospital, Napoli, Italy; Department of Precision Medicine, University of Campania 'L. Vanvitelli' Napoli, Italy. Electronic address:
Infection
October 2023
Unit of Infectious and Transplant Medicine, AORN Ospedali dei Colli-Monaldi Hospital, Piazzale Ettore Ruggieri, 80131, Naples, Italy.
J Infect Public Health
September 2023
Department of Mental Health and Public Medicine - Infectious Diseases Unit. University of Campania Luigi Vanvitelli, Naples, Italy. Electronic address:
Background: No clear evidence supports the use of cefiderocol as first line treatment in A. baumannii infections.
Methods: We conducted an observational retrospective/prospective multicenter study including all patients> 18 years with carbapenem-resistant A.
Expert Rev Anti Infect Ther
June 2023
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Introduction: Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) are a common reason of Emergency Department (ED) access and account for a considerable number of hospital admissions and a high economic burden for the healthcare system. The long-acting lipoglycopeptides (LALs) allow for an outpatient management of subjects with ABSSSIs, still requiring parenteral therapy, but who do not need hospitalization.
Areas Covered: The following topics were addressed: i) microbiological activity, efficacy, and safety of dalbavancin, ii) critical steps for the management of ABSSSIs in the ED (decision to hospitalize, risk of bacteremia and infection recurrence), iii) feasibility of direct/early discharge from the ED and potential advantage of dalbavancin.
Microbiol Spectr
June 2023
National Institute for Antibiotic Resistance and Infection Control, Israel Ministry of Health, Tel Aviv, Israel.
Rev Cardiovasc Med
May 2023
Cardiology Unit, Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", AORN Ospedali dei Colli Monaldi Hospital, 80131 Naples, Italy.
Sudden cardiac death (SCD) is one of the leading causes of cardiovascular death in general population. SCD primary prevention requires the correct selection of patients at increased risk who may benefit from implantable cardioverter-defibrillator (ICD). Despite several non-invasive arrhythmic risk indexes are available, their ability to stratify the SCD risk among asymptomatic patients with cardiac disease at increased arrhythmic risk is debated.
View Article and Find Full Text PDFInt J Antimicrob Agents
July 2023
First Division of Infectious Diseases, Cotugno Hospital, Azienda Ospedaliera dei Colli, Naples, Italy.
Background: Ceftobiprole is approved in Europe for treatment of community-acquired pneumonia and non-ventilator-associated hospital-acquired pneumonia (HAP) in adults. Real-world data are limited.
Methods: This multi-centre, observational, ambispective investigator-initiated study was undertaken in Italy from January 2018 to December 2019 in order to evaluate the use of ceftobiprole in a real-world setting.
Antibiotics (Basel)
February 2023
Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Multidrug-resistant (MDR)/extensively drug-resistant (XDR) is emerging as a major threat related to adverse patient outcomes. The goal of this review is to describe evidence-based empiric and targeted treatment regimens that can be exploited when dealing with suspected or confirmed infections due to MDR/XDR . has inherent resistance to many drug classes, the capacity to form biofilms, and most importantly, the ability to quickly acquire resistance to ongoing treatments.
View Article and Find Full Text PDFInt J Antimicrob Agents
February 2023
Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; Unit of Infectious and Transplant Medicine, AORN Ospedali dei Colli-Monaldi Hospital, Piazzale Ettore Ruggieri, 80131 Naples, Italy. Electronic address:
Objectives: Cefiderocol is a 'siderophore' cephalosporin active against Gram-negative bacteria, including carbapenem-resistant strains. Data on the use of cefiderocol in real life are limited. We evaluated the efficacy and safety of cefiderocol in the context of our hospital clinical practice.
View Article and Find Full Text PDFAnn Pediatr Cardiol
November 2022
Department of Paediatric Cardiology, AORN Ospedali dei Colli Monaldi Hospital, University of Campania "L. Vanvitelli", Naples, Italy.
We report a rare case of vascular ring due to a left cervical circumflex aortic arch with aberrant right subclavian artery arising from a Kommerell diverticulum. This is a very rare case of vascular ring in a newborn with stridor and stenosis of the left pulmonary artery. A cardiac catheterization and an angio-computed tomography scan were helpful to clarify the diagnosis.
View Article and Find Full Text PDFJ Endourol
March 2023
Department of Urology, Careggi Hospital, University of Florence, San Luca Nuovo, Florence.
Water vapor intraprostatic injection (Rezum procedure) for benign prostatic hyperplasia (BPH) is one of the most promising minimally invasive surgical treatments. Five-year outcomes from the multicenter randomized controlled trial (RCT) demonstrated significant and durable urinary and sexual function results in selected patients. We compared the sexual and urinary outcomes of this procedure in patients satisfying inclusion criteria of the RCT with unselected patients.
View Article and Find Full Text PDFBiomedicines
October 2022
Unit of Infectious and Transplant Medicine, AORN Ospedali dei Colli-Monaldi Hospital, Piazzale Ettore Ruggieri Snc, 80131 Naples, Italy.
Diabetes mellitus (DM) arising after transplant is a common complication, sharing many features with type 2 DM but also specific causes, such as administration of steroids and immunosuppressive drugs. Although post-transplant DM (PTDM) is generally assumed to worsen recipients' outcomes, its impact on renal function, cardiac allograft vasculopathy and mortality remains understudied in heart transplant (HT). We evaluated incidence and risk factors of PTDM and studied glucose metabolic alterations in relation to major HT outcomes.
View Article and Find Full Text PDFAntibiotics (Basel)
October 2022
Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via de Crecchio 7, 80138 Napoli, Italy.
(1) Background: The aim of this study was to assess the clinical and microbiological characteristics of multidrug-resistant infections in a neuromuscular semi-intensive/sub-intensive care unit; (2) Methods: Retrospective analysis on data from 18 patients with NMD with proven MDRO/XDRO colonisation/infection from August 2021 to March 2022 was carried out; (3) Results: Ten patients were males (55.6%), with a median age of 54 years, and there were fourteen patients (77.8%) with amyotrophic lateral sclerosis.
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