71 results match your criteria: "AL Zahra University[Affiliation]"

Introduction: Traffic accidents are a major public health concern worldwide, resulting in significant injuries, fatalities, and economic costs. In urban zones, traffic accident dynamics can vary significantly due to population density, infrastructure, and emergency response capabilities. The present study was conducted to determine the time intervals of prehospital emergencies in traffic accidents by separating the 15 zones of Isfahan city, Iran.

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The combining of therapeutic agents with electrospun nanofibers boosts their regeneration potential; therefore, Researchers have increasingly turned towards the development of electrospun nanofiber scaffolds to encapsulate or surface-adsorb biological payloads, such as cytokines, exosomes, peptides, nucleic acids, and enzymes. Due to their high surface-to-volume ratio, ease of manufacturing, and drug-loading capacity, electrospun nanofibers are hopeful in tissue engineering and scaffold fabrication. Electrospun multilayer scaffolds offer a promising construction for preserving the integrity and bioactivity of therapeutic factors while permitting the controlled and prolonged release of biomolecules into the environment.

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Traumatic brain injury (TBI) is a common problem in elderly individuals, with significant morbidity and mortality. The elderly Traumatic Brain Injury (eTBI) score, a novel tool for predicting outcomes in elderly patients with TBI, has shown promising results in previous studies. This study aimed to validate the eTBI score in a larger cohort of elderly patients with TBI in the Middle East.

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Article Synopsis
  • - The study compares two surgical methods for treating acetabular fractures: the ilioinguinal approach (IA) and the modified Stoppa approach (MSA), focusing on their effectiveness and outcomes.
  • - Findings reveal that the MSA resulted in significantly less blood loss during surgery (404.36 vs. 650.92 ml) and a shorter duration (average 141.88 min vs. 172.24 min), although both approaches had similar infection rates and nerve injury incidences.
  • - The conclusion indicates that the MSA is the preferred method due to its advantages in blood loss, but further research is needed to confirm these results.
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Background: Amniotic Band Syndrome (ABS) is a rare congenital condition characterized by the formation of fibrous bands within the amniotic sac that can entangle and restrict fetal development, leading to various deformities. In this report, we present an unprecedented case of fetal amniotic band ingestion in a monochorionic diamniotic (MCDA) twin pregnancy. Reporting this case is essential for expanding the understanding of the diverse presentations of amniotic bands, considering this rare entity in the differential diagnosis of prenatal ultrasound findings, and emphasizing the importance of vigilant prenatal monitoring and individualized management strategies.

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Background: Blunt trauma is a physical injury to a part of the body, mainly caused by road accidents, direct blows, attacks, sports injuries, and falls in elderly people. Spinal fractures are observed only in a small percentage of injured patients. Accordingly, the present study was conducted on collected data between 2018 and 2022 to determine the frequency of spinal fractures in blunt trauma in Iran while also considering the mechanism of injury as a secondary outcome of interest.

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Pure spinal multiple sclerosis: A case series of a possible new entity.

J Neuroimmunol

January 2025

Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Article Synopsis
  • A recent study examined a condition called "pure spinal" MS, which features demyelination mainly in the spinal cord, potentially responding well to disease-modifying treatments (DMT).
  • Researchers analyzed data from around 8000 patients and identified 7 women with this condition, averaging 40 years old and having positive markers in their cerebrospinal fluid indicative of demyelination.
  • Treatment with DMT resulted in reduced relapse rates and stabilization of symptoms in these patients, suggesting that pure spinal MS may merit further study and could lead to updates in diagnostic criteria for MS.
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Background: Papillary thyroid carcinoma (PTC) is also the most common endocrine malignancy. In the present study, we aimed to evaluate the metastasis pattern of upper mediastinal lymph node involvement in patients with PTC.

Materials And Methods: This is a descriptive cross-sectional study that was performed in 2020 in Isfahan, Iran, on 73 patients with PTC who were candidates for total thyroidectomy.

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Introduction: This study aims to investigate the effectiveness of intravenous ibuprofen or intravenous ibuprofen plus acetaminophen compared to intravenous morphine in patients with closed extremity fractures.

Methods: A triple-blinded randomized clinical trial was conducted at a tertiary trauma center in Iran. Adult patients between 15 and 60 years old with closed, isolated limb fractures and a pain intensity of at least 6/10 on the visual analog scale (VAS) were eligible.

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This study compared the effect of the conventional technique of procedural sedation and the mini-dose intravenous regional anesthesia (IVRA). 45 patients received IVRA, and 47 received iv. ketamine.

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Experiences of Nurses in Caring for Patients with COVID-19: A Qualitative Research.

Iran J Nurs Midwifery Res

June 2023

Nursing and Midwifery Care Research Center, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The Covid-19 disease was raised as a fundamental public health problem worldwide, and nurses were exposed to many problems and challenges at the front line of fighting this disease. Therefore, the present study aimed to explain the experiences of nurses who took care of Covid-19 patients.

Materials And Methods: This study was a conventional content analysis qualitative study using Granheim and Lundman approach.

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Background: With increasing age and joint-destructive diseases, the need for novel surgeries such as total knee arthroplasty (TKA) has increased. Complications such as pain exacerbation and persistent pain after surgery may occur which increases rehabilitation programs. Factors such as body mass index (BMI), psychiatric disorders, spine diseases, and comorbidities diseases can affect outcomes.

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Background: We aimed to better understand the outcomes/complications of pie-crusting technique using blade knife during total knee arthroplasty (TKA) in patients with knee genu varum deformity.

Materials And Methods: A systematic search was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. English and Persian language articles were considered on the use of pie-crusting technique during TKA in patients with knee genu varum/varus deformity using related keywords and Medical Subject Headings terms with reported postoperative complications and outcomes.

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Neuromyelitis optica spectrum disorder is an autoimmune disease which tends to have other coexisting autoimmune or connective tissue diseases. However, coexisting with ankylosing spondylitis is rare. Here, we report a 57-year-old man with concomitant autoantibodies against aquaporin 4-positive neuromyelitis optica spectrum disorder and HLA-B27-positive ankylosing spondylitis.

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Aim: The purpose of this research was to identify the perceived stress, stress coping strategies, and Post-Traumatic-Growth (PTG) among Iranian healthcare professionals.

Design: A cross-sectional study was applied.

Methods: This study was conducted among 402 healthcare professionals in northwestern Iran.

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Anti-glutamic acid decarboxylase (Anti-GAD) are associated with various neurologic condition; but no meningitis has been reported with it, so far. Evidence demonstrates the associated of autoimmune meningoencephalitis with COVID-19 infection. Here, we report a 44-year-old female with progressive loss of consciousness with anti-GAD65 meningoencephalitis 1 month after COVID-19 infection.

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Bone Health after Bariatric Surgery: Consequences, Prevention, and Treatment.

Adv Biomed Res

October 2022

Isfahan Minimally Invasive Surgery and Obesity Research Center, School of Medicine, Al-Zahra University Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

One of the most critical complications of bariatric surgery (BS), which has been widely discussed recently, is its adverse effects on the health of the bones and skeletal system. Studies show that bone mineral density (BMD) decreases significantly in the early years after BS Nutritional deficiencies are a common complication of BS that can last for months to years after surgery. For example, calcium absorption will significantly reduce after BS The role of gut hormones, endocrine factors, and adipokines in altering bone metabolism should never be overlooked.

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Article Synopsis
  • The study examined the antibacterial properties of microalgae extracts from the Persian Gulf against various Gram-positive and Gram-negative bacteria to identify potential new antibacterial compounds.
  • The methanolic extract demonstrated stronger antibacterial effects compared to the ethyl acetate extract, with notable effectiveness observed at a concentration of 500 mg/ml.
  • Findings confirm the potential of Persian Gulf microalgae extracts as natural antimicrobials, suggesting their use in pharmaceutical applications for treating bacterial infections.
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The present study aimed to prepare and evaluate a controlled-release system based on a chitosan scaffold containing selenium nanoparticles loaded with doxycycline. Its topical application in skin wound healing in rats was investigated. Therefore, 80 female rats were used and, after creating experimental skin defects on their back, were randomly divided into four equal groups: the control group without any therapeutic intervention; the second group received a chitosan transdermal patch (Ch); the third group received chitosan transdermal patch loaded with selenium nanoparticles (ChSeN), and the last group received chitosan transdermal patch containing selenium nanoparticle loaded by doxycycline (ChSeND).

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Background And Purpose: Most patients experience anxiety before heart surgery. On the other hand, spiritual health can improve the candidate patient's adaptation to surgery. Therefore, this study aimed to investigate the effect of group logotherapy on spirituality and anxiety of patients undergoing cardiac surgery.

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COVID19 vaccine rejection is a global issue that most developing countries face. A study of COVID-19 vaccine preference among Al-Zahraa University female students will pave the way to resolving the issue of vaccine rejection among students. Vaccine hesitation refers to a delay in accepting or refusing immunization despite the fact that vaccination services are readily available.

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Objective: Coenzyme Q10 gel might be beneficial for periodontitis. However, the results have been controversial. We designed a systematic review and meta-analysis to explore the efficacy of coenzyme Q10 in periodontitis patients.

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Novel COVID-19 is a public health emergency that poses a serious threat to people worldwide. Given the virus spreading so quickly, novel antiviral medications are desperately needed. Repurposing existing drugs is the first strategy.

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Background: Oxidative stress that occurs as a consequence of the imbalance between antioxidant activity and free radicals can contribute in the pathogenesis of metabolic disorders, such as type 2 diabetes mellitus (T2DM). Antioxidant therapies have been proposed as possible approaches to treat and attenuate diabetic complications. The purpose of this study was to evaluate potential antioxidant effects of trehalose on oxidative indices in a streptozotocin (STZ)-induced diabetic rat model.

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Coronavirus disease 2019 (COVID-19) is spreading rapidly and has affected millions of people worldwide. Comorbid diseases have complicated the course of infection and increased mortality. Myasthenia gravis (MG) affects the neuromuscular junctions (NMJs) and can compromise respiratory muscle action, leading to worse clinical outcomes in individuals infected with the COVID-19 theoretically.

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