104 results match your criteria: "AHEPA University Hospital of Thessaloniki[Affiliation]"

Isolated iliac aneurysms are rare, and their management becomes complex when accompanied by ectopic pelvic kidneys due to altered vascular anatomy. We report a 58-year-old male with an incidentally discovered 53.5 mm left common iliac artery (CIA) aneurysm and an ectopic pelvic kidney.

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The "streamline flow" of the portal vein (PV) is a controversial yet well-known theory presented almost 125 years ago. It states that blood from the superior mesenteric vein (SMV) goes preferentially to the right liver lobe, while splenic and inferior mesenteric veins divert blood predominantly to the left lobe, affecting this way the metastatic distribution of colorectal cancer (CRC). The aim of this systematic review is to assess its validity by examining and combining all the relevant literature with a critical eye.

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Background Pediatric vascular trauma, although rare, poses significant clinical challenges due to the potential for long-term morbidity, including limb compromise and growth abnormalities. This study addresses the gap in standardized treatment protocols by evaluating the efficacy of heparin-based conservative treatments compared to surgical interventions in children under 13 years of age. Methods A retrospective observational study was conducted at a referral center, reviewing institutional records from January 2010 to December 2020.

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Introduction: Do we form mental models which bear an analogical relation to the real world like those of a photograph? Has the language of thought an analogue nature (it makes use of mental imagery) or whether it is exclusively of digital nature like language?

Objectives: The basic aim of the present study is to contribute to the ongoing work on mental imagery by extending the research to an unexplored area that of mental partitioning.

Methods: The present research sample consisted of 498 participants (234 males and 264 females). We used the SPSS software package in order to analyze our data.

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Background: Coronary computed tomography angiography (CCTA) in patients with post-coronary artery bypass graft (CABG) has a high diagnostic accuracy for visualization of grafts. Invasive coronary angiography (ICA) in patients with CABG is associated with increased procedural time, contrast agent administration, radiation exposure, and complications, compared with non-CABG patients. The aim of this multicenter, randomized controlled trial was to compare the strategy of CCTA-guided ICA versus classic ICA in patients with prior CABG.

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Osteokines in Nonalcoholic Fatty Liver Disease.

Curr Obes Rep

December 2024

First Laboratory of Pharmacology, School of Medicine, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

Purpose Of Review: To critically summarize evidence on the potential role of osteokines in the pathogenesis and progression of nonalcoholic fatty liver disease (NAFLD).

Recent Findings: There are emerging data supporting that certain osteokines, which are specific bone-derived proteins, may beneficially or adversely affect hepatic metabolism, and their alterations in the setting of osteoporosis or other bone metabolic diseases may possibly contribute to the development and progression of NAFLD. There is evidence showing a potential bidirectional association between NAFLD and bone metabolism, which may imply the existence of a liver-bone axis.

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Article Synopsis
  • - Hodgkin lymphoma (HL) is a rare type of cancer that features specific cells called Hodgkin or Reed-Sternberg cells.
  • - Cardiac issues related to HL are not well-studied, with limited reports on conditions like cardiac tamponade in these patients.
  • - A case is presented of a 21-year-old woman whose initial HL symptoms included cardiac tamponade, underscoring the need for quick diagnosis and treatment of related heart complications.
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Thyroid cancer and pregnancy: a systematic ten-year-review.

Gland Surg

June 2024

1st Propedeutic Department of Surgery, AHEPA University Hospital of Thessaloniki, School of Medicine, Aristotle University, Thessaloniki, Greece.

Background: Thyroid cancer is the second most common malignancy during pregnancy, especially the well-differentiated thyroid cancer (well-DTC). Therefore, complex medical and social dilemmas arise, dealing with which requires deep knowledge of the nature and characteristics of the disease and pregnancy as a whole. The purpose of this review is to present the diagnostic and therapeutic strategies of thyroid cancer during pregnancy and the postpartum period.

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Background: To systematically evaluate the prognostic utility of estimated plasma volume status (ePVS) on the outcomes of patients undergoing transcatheter aortic valve implantation (TAVI).

Methods: The exposure variable of interest was the ePVS, enumerating the percentage change of the actual plasma volume from the ideal plasma volume, and being calculated on the basis of weight and hematocrit using sex-specific constants. A random-effects meta-analysis was performed after a systematic literature search in PubMed, Scopus and Web Of Science.

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Article Synopsis
  • The study explored how the KRAS biomarker can predict treatment outcomes for patients with advanced non-small cell lung cancer (NSCLC) receiving immune checkpoint inhibitors (ICIs) and chemotherapy.
  • It included 100 male patients, mostly with adenocarcinoma; KRAS G12C mutations were found in 73% of samples, and overall survival was significantly better for patients with negative KRAS results.
  • Findings suggest that KRAS mutations are linked to poorer survival rates in NSCLC patients after immunotherapy, regardless of PDL1 expression levels.
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BACKGROUND Schwannomas are tumors that arise from Schwann cells that surround and support nerve cells. Most common sites for presentations are head, neck, and extremities. Schwannomas of gastrointestinal tract are rare, slow-growing tumors, usually benign, arising from gastrointestinal tract's neural plexus.

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Article Synopsis
  • * A case study discusses a 76-year-old man who had a sigmoid tumor causing bowel obstruction and a suspected liver metastasis, leading to simultaneous surgical procedures: Hartmann's sigmoidectomy and left lateral hepatic resection.
  • * Despite significant blood loss during surgery and a postoperative pulmonary embolism, the patient was discharged 21 days later and showed no active disease after adjuvant chemotherapy, highlighting the need for more research on simultaneous CRCa and metastasis surgeries in emergency situations.
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Purpose: This study aims to investigate whether routine screening for silent pulmonary embolism (PE) can be justified in patients with deep vein thrombosis (DVT).

Materials And Methods: We retrospectively analyzed the medical records of 201 patients with lower-extremity DVT admitted to the vascular surgery department of a single tertiary university center between 2019 and 2023. All patients underwent clinical evaluation, basic laboratory exams, a whole-leg colored duplex ultrasound, and a computed tomography pulmonary angiography (CTPA), to screen for an occult, underlying PE.

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Background: A coronary artery aneurysm (CAA) is an abnormal dilation of a coronary artery segment often accompanied by coronary artery fistula (CAF), leading to communication between a coronary artery and a cardiac chamber or a part of the coronary venous system. Both CAAs and CAFs can present with symptoms and signs of myocardial ischemia and infarction.

Case Presentation: We describe the case of a 46-year-old woman with non-ST-elevation myocardial infarction (NSTEMI) caused by a "giant" CAA.

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: Despite the increasing use of biomarkers, differentiation between Alzheimer's disease (AD), behavioral variant Frontotemporal Dementia (bvFTD), and Primary Progressive Aphasia (PPA) remains a challenge. Apraxia is a supportive feature for diagnosing AD but is underrepresented in other dementia types. Herein, we investigated the presence and characteristic profiles of limb, verbal, and non-verbal apraxia in three major dementia types.

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Article Synopsis
  • - Prolactin (PRL) is a hormone produced by the anterior pituitary and has been linked to various health outcomes, particularly its potential implications for mortality risk in adults without prolactinoma.
  • - A systematic review of 28 studies involving 23,596 individuals found that higher serum PRL levels correlate with increased risks of all-cause and cardiovascular mortality.
  • - Despite these findings suggesting PRL could serve as a mortality predictor, further research is needed to confirm its effectiveness in clinical risk assessment.
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Crossed fused renal ectopia (CFRE) constitutes a rare congenital anomaly of the urinary tract, typically characterized by its predominantly asymptomatic nature and frequent incidental discovery. This case report delineates the clinical profile of a 56-year-old male admitted to our Prostate Cancer Outpatient Clinic due to elevated prostate-specific antigen (PSA) levels, ultimately leading to the diagnosis of prostate cancer. The patient was asymptomatic, with no family or surgical background.

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(1) Background: Thoracic epidural analgesia is considered the gold standard in post-operative pain management following thoracic surgery. This study was designed to explore the safety of thoracic epidural analgesia and to quantify the incidence of its post-operative complications and side effects in patients undergoing thoracotomy for major surgery, such as resection of lung malignancies and lung transplantation. (2) Methods: This is a retrospective, dual-center observational study including patients that underwent major thoracic surgery including lung transplantation and received concurrent placement of thoracic epidural catheters for post-operative analgesia.

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Periostin, a secreted matricellular protein, has been implicated in cardiac extracellular matrix remodeling and fibrosis. Evidence suggest that periostin stimulates cardiomyocyte hypertrophy. The current study aims to investigate the extent of periostin expression in patients with advanced Hypertrophic Cardiomyopathy (HCM) and its correlation with fibrosis and hallmark histopathological features of the disease.

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Article Synopsis
  • * A significant number of patients with acute DVT experience recurrent VTE events and may develop CPC, highlighting the complications associated with VTE.
  • * Imaging techniques are crucial for diagnosing both acute and chronic venous diseases, with venous duplex ultrasound being the primary method for acute DVT, while CPC diagnosis may require more complex imaging methods.
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The impact of high-intensity interval training (HIIT) on the central nervous system (CNS) in autoimmune neuroinflammation is not known. The aim of this study was to determine the direct effects of HIIT on the CNS and development of experimental autoimmune encephalomyelitis (EAE). Healthy mice were subjected to HIIT by treadmill running and the proteolipid protein (PLP) transfer EAE model was utilized.

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Background: Acute myocardial infarction (AMI) remains a major cause of death worldwide. Survivors of AMI are particularly at high risk for additional cardiovascular events. Consequently, a comprehensive approach to secondary prevention is necessary to mitigate the occurrence of downstream complications.

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Introduction: Chios Mastiha essential oil (CMO) is a natural product extracted from the resin of Mastiha, possessing antioxidant, anti-microbial, anti-ulcer, anti-neoplastic, and cholesterol-lowering capabilities in vitro, and its hypolipidemic effect was confirmed in animal studies. Yet, there are no randomized, placebo-controlled clinical studies in the literature regarding CMO's hypolipidemic effects in humans. A prospective, randomized, placebo-controlled study was designed to study the hypolipidemic effect of CMO capsules on healthy volunteers with elevated cholesterol.

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