214 results match your criteria: "ACS Medical College[Affiliation]"

Article Synopsis
  • * Autologous conditioned serum (ACS) therapy uses a patient's own blood to produce growth factors and anti-inflammatory substances, showing significant promise in reducing pain and improving knee function in patients with OA, based on a review of 18 clinical studies.
  • * Findings indicate that ACS therapy can be as effective or better than conventional treatments like platelet-rich plasma and steroids, with minimal adverse effects reported and potential benefits for tissue repair and disease modification.
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OrthoTV has emerged as a pioneering platform in the field of orthopedic education, leveraging technology to create a comprehensive and accessible knowledge repository. Originating from the vision of the Indian Orthopedic Research Group in 2013, OrthoTV has evolved into a global educational hub, streaming thousands of hours of surgical videos, webinars, and podcasts. It provides a dynamic learning environment through live interactive sessions, fostering real-time engagement with experts and facilitating a global exchange of knowledge.

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Background Smokeless tobacco (SLT) use, particularly gutkha, is prevalent in India, with cultural acceptance contributing to widespread use, especially among tribal populations. Despite awareness programs, there is limited assessment of their effectiveness, leading to continued vulnerability, even among educated groups. This study aims to evaluate public health strategies by developing and validating the SLT Awareness, Attitude, and Response Knowledge (STAARK) scale, which assesses knowledge and attitudes post-awareness programs on SLT usage through questionnaires, identifying vulnerable individuals, and enabling targeted interventions to reduce SLT use and associated health risks, particularly through integrated risk assessment (IRA).

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In recent years, systemic inflammation has emerged as a pivotal player in the development and progression of various degenerative diseases. This complex, chronic inflammatory state, often undetected, can have far-reaching consequences for the body's physiology. At the molecular level, markers such as C-reactive protein, cytokines and other inflammatory mediators serve as indicators of systemic inflammation and often act as predictors of numerous musculoskeletal diseases and even certain forms of cancer.

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Background: The advent of tissue engineering and regenerative medicine has introduced innovative approaches to treating degenerative and traumatic injuries, particularly in cartilage, a tissue with limited self-repair capabilities. Among the various stem cell sources, umbilical cord-derived mesenchymal stromal cells (UC-MSCs) have garnered significant interest due to their non-invasive collection, minimal ethical concerns, and robust regenerative potential, particularly in cartilage regeneration.

Methods: A comprehensive literature review was conducted using multiple databases, including PubMed, Scopus, Web of Science, and Google Scholar.

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Unlabelled: Operating room fires are considered 'never events'; they are uncommon but can prove to be potentially damaging to the humans involved and the expensive operating room instrumentation. Research indicates that significant knowledge gaps exist in orthopaedic community relating to fire prevention, fire safety and fire management. A 24-year-old male patient with clavicle fracture was planned for surgical fixation.

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Decoding the hidden realm: Molecular pioneering unravelling osteoarticular tuberculosis diagnosis.

J Clin Orthop Trauma

September 2024

Trauma and Orthopaedic Surgeon, Southport and Ormskirk Hospitals, Mersey and West Lancashire Teaching NHS Trust, Southport, PR8 6PN, United Kingdom.

Article Synopsis
  • Osteoarticular tuberculosis (TB) affects the bones and joints and is a rare type of TB that makes up about 1-3% of all cases.
  • Diagnosing it quickly is really important, but traditional methods for testing have some problems, like taking too long and not always being accurate.
  • New tests that look at the DNA of the bacteria causing TB may help diagnose it faster and more accurately, but more studies are needed to figure out how well these tests work and to find ways to improve them.
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The healthcare sector faces complex challenges that call for innovative solutions to improve diagnostic accuracy, treatment efficacy, and data management. Quantum computing, with its unique capabilities, holds the potential to revolutionize various aspects of healthcare. This narrative review critically examines the existing literature on the application of quantum computing in healthcare, focusing on its utility in enhancing diagnostics, data processing, and treatment planning.

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Extrapulmonary tuberculosis is less commonly reported, and isolated tuberculous involvement of bones such as the radius, without any pulmonary lesions, is extremely rare. Diagnosing this condition can be challenging due to ambiguous clinical features and non-specific radiological findings in the early stages. The present case describes a rare instance of isolated tuberculosis of the radius in an immunocompetent Indian male with no pulmonary involvement.

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Tuberculous infection of the extrapulmonary sites, especially the small bones, is a seldom reported entity even in endemic countries. Moreover, simultaneous involvement of the forearm muscles is a very rare presentation with no such case reported showing concurrent involvement of the two sites. The diagnosis is challenging due to the paucibacillary nature of the disease, a lack of awareness among primary clinicians, and ambiguity in clinical features with other musculoskeletal disorders, especially when there is no pulmonary involvement.

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Type II diabetes mellitus (T2DM) has experienced a dramatic increase globally across countries of various income levels over the past three decades. The persistent prevalence of T2DM is attributed to a complex interplay of genetic and environmental factors. While numerous pharmaceutical therapies have been developed, there remains an urgent need for innovative treatment approaches that offer effectiveness without significant adverse effects.

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The integration of fog computing into healthcare promises significant advancements in real-time data analytics and patient care by decentralizing data processing closer to the source. This shift, however, introduces complex regulatory, privacy, and security challenges that are not adequately addressed by existing frameworks designed for centralized systems. The distributed nature of fog computing complicates the uniform application of security measures and compliance with diverse international regulations, raising concerns about data privacy, security vulnerabilities, and legal accountability.

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Soft-tissue Chondroma Masquerading as Chondroid Syringoma - A Case Report.

J Orthop Case Rep

September 2024

Department of Orthopaedics, ACS Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai, Tamil Nadu, India.

Article Synopsis
  • Soft-tissue chondromas are uncommon, benign tumors found mainly in the extremities, often diagnosed in middle-aged individuals, and can be tough to identify due to their slow growth and similarity to other tumors.
  • A case study highlights a 27-year-old male with a painful, enlarging mass on his toe, which underwent various diagnostic imaging techniques before being surgically removed and identified as a soft-tissue chondroma.
  • Proper diagnosis and management are essential, as these tumors, while benign, can significantly affect a person's quality of life and may require careful evaluation to avoid unnecessary treatments.
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The doctor-patient relationship, once grounded in trust and mutual respect, is increasingly marred by incidents of violence against healthcare providers. This alarming trend not only threatens the safety of doctors but also undermines the integrity of medical care. This article delves into the multifaceted reasons behind such violence, exploring emotional, financial, societal, and systemic factors that contribute to this disturbing phenomenon.

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Surgical training has long emphasized learning through direct observation, allowing young surgeons to gain practical insights from experienced surgeons. The advent of live surgical demonstrations has extended this learning method, providing real-time broadcasts of surgeries to wider audiences. Live surgery is a surgery that is broadcasted in real time to an audience.

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Novel investigations of how microgravity affects cellular and tissue development have recently been made possible by the multidisciplinary fusion of tissue engineering and space science. This review examines the intersection of cartilage tissue engineering (CTE) and space science, focusing on how microgravity affects cartilage development. Space microgravity induces distinct physiological changes in chondrocytes, including a 20-30% increase in cell diameter, a 1.

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Pulmonary tuberculosis (PTB), human immunodeficiency virus (HIV), and leprosy are of public health importance, as all three diseases are communicable and contribute to disease burden in society. Co-infection with these three entities is extremely rare but leads to significant mortality and morbidity. We report a case that highlights the diagnostic challenges and therapeutic management of a patient who was diagnosed with pure neuritic leprosy on multibacillary-multidrug therapy (MB-MDT) and subsequently co-diagnosed with PTB and HIV.

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Context: Water is a basic human right essential to all for sustainable development. Sanitation is one of the determinants of quality of life and the human development index. Drinking unsafe water impairs health through illnesses such as diarrhoea, and untreated excreta contaminates ground waters and surface waters used for drinking, bathing and household purposes.

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Introduction: Spinal cord injury (SCI) may bring lifelong consequences for affected patients and a high financial burden to the health care system.

Source Of Data: Published peer-reviewed scientific articles identified from EMBASE, Google Scholar, PubMed and Scopus.

Areas Of Agreement: Surgery and blood pressure management are the main targets in acute SCI to avoid secondary damage.

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Article Synopsis
  • The review focuses on the critical process of isolating mesenchymal stromal cells (MSCs) from the stromal vascular fraction (SVF) of adipose tissue, emphasizing factors like technique and immediate processing that affect cell functionality.
  • It highlights the importance of fine-tuning enzymes during digestion, detailed filtration and centrifugation methods for purifying SVF, and assessing cell viability through techniques like flow cytometry.
  • The conclusion calls for standardized protocols in MSC isolation to enhance reproducibility, along with ongoing research and collaboration to ensure patient safety and improve regenerative medicine outcomes.
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Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still needs to be discovered. Despite causing fewer adverse effects when compared to other analgesics, its harmful effects on the blood and lack of evidence regarding its teratogenicity make the usage of the drug questionable, which has led to it being removed from the drug market of various countries.

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Introduction: Needlestick and sharps injuries (NSSIs) represent an existential occupational hazard risk to orthopaedic surgeons during their career due to the interaction with various devices, instruments and bone fragments. Consequently, NSSIs have the potential to transmit infections such as Hepatitis B (HBV), Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV) leading to serious illness. The purpose of this cross-sectional study was to identify the clinical settings predisposing orthopaedic surgeons to NSSIs and assess their adherence to safety protocols in the Indian context.

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Bilateral Subluxation of the Proximal Tibiofibular Joint: A Rare Case Report.

J Orthop Case Rep

August 2024

Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Chennai, Tamil Nadu, India.

Introduction: Proximal tibiofibular joint (PTFJ) subluxations are rare and can occur following trauma or sporting events. Idiopathic PTFJ subluxations are more common in females and in patients with generalized ligament laxity. The proper history and clinical examination together with imaging can help in establishing the diagnosis in the majority of cases.

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Article Synopsis
  • Osteonecrosis of the femoral head (ONFH) is a debilitating condition caused by reduced blood supply, making treatment challenging, with Bone Marrow Aspirate Concentrate (BMAC) showing promise as a less invasive alternative for relief and improved function.
  • A study involving 20 patients who had unsuccessful results from traditional treatments used BMAC from bone marrow to manage ONFH, with outcomes measured over a period of 24 months.
  • Results indicated significant pain reduction and improved hip function, although some patients experienced complications like symptom recurrence and ongoing pain, reinforcing the need for careful patient management.
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Blood donation, a fundamental act of altruism, has undergone significant evolution over the centuries. Despite medical progress, the persistent challenge lies in securing an adequate supply of blood and its derivatives. This article critically examines the proposal to introduce monetary incentives for blood donation, delving into ethical, legal, and pragmatic dimensions.

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