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Trial of metronidazole vs. azithromycin for treatment of cyclosporine-induced gingival overgrowth.
Pediatr Transplant
February 2004
Division of Pediatric Nephrology and Hypertension, The Children's Hospital at The Cleveland Clinic Foundation, A120 Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Gingival overgrowth usually characterized by increased cellular growth of gingival fibroblasts appears to be multifactorial. In patients receiving CyA for more than 3 months, the incidence can approach 70% and can be attributed to pharmaceutical immunosuppression. Case reports have reported regression of overgrowth with both metronidazole and azithromycin.
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