Implantation of a mitral allograft into the tricuspid valve position in active infective endocarditis.

In cases of severe and recurrent infectious lesions affecting the right heart, one alternative option for bioprosthetic intervention is the implantation of a mitral allograft (a donor heart valve) in the position of the tricuspid valve. We present a clinical case detailing the successful implantation of a fresh mitral allograft into the tricuspid position in a 37-year-old male patient diagnosed with active infective endocarditis of the tricuspid valve and a high risk of prosthetic endocarditis. The mitral allograft was anatomically implanted with annuloplasty using an expanded polytetrafluoroethylene band.

[Morphology of the myocardium of the interventricular septum in children with hypertrophic cardiomyopathy].

Objective: To carry out a comparative analysis of the morphology of the interventricular septum (IVS) myocardium in children with hypertrophic cardiomyopathy (HCM) and without cardiovascular pathology.

Material And Methods: A study of myocardial biopsies of the IVS in children with HCM (=18, 1.2-17 years) and children without cardiovascular pathology (=11, 1-16 years) was carried out.

Morphological Features of the Ascending Aorta Remodeling and Activation of Regeneratory Potential in Intima when Forming Aneurysm.

In patients with an ascending aorta aneurysm, restructuring of all its layers and, first of all, the intima and media was revealed. The thickness of the intima was 79.3±63.

Microwave Near-Field Dynamical Tomography of Thorax at Pulmonary and Cardiovascular Activity.

The developed near-field microwave diagnostics of dynamical lung tomography provide information about variations of air and blood content depth structure in the processes of breathing and heart beating that are unattainable for other available methods. The method of dynamical pulse 1D tomography (profiling) is based on solving the corresponding nonlinear ill-posed inverse problem in the extremely complicated case of the strongly absorbing frequency-dispersive layered medium with the dual regularization method-a new Lagrange approach in the theory of ill-posed problems. This method has been realized experimentally by data of bistatic measurements with two electrically small bow-tie antennas that provide a subwavelength resolution.

Mid-regional pro-adrenomedullin as a predictor of in-hospital mortality in adult patients with COVID-19: a single-centre prospective study.

Background: To determine the predictive value of mid-regional pro-adrenomedullin (MR-proADM) compared to routine clinical and laboratory parameters in patients with COVID-19.

Methods: A total of 135 adult patients hospitalized with COVID-19 were included in a prospective single-centre study. In addition to routine parameters, the levels of MR-proADM in blood plasma were measured on the day of hospitalization.

[Actual privy councilor V.V. Pelikan (1790-1873) and his 'Dissertatio medico chirurgica inauguralis de aneurysmate' (ST. Petersburg, 1816). Part 3].

The article deals with the analysis of the translated for the first time from Latin to Russia and introduced into scientific use 'Dissertatio medico chirurgica inauguralis de Aneurysmate' (St. Petersburg, 1816) written by Associate Professor of the Imperial Medical and Surgical Academy, then holder of the highest orders of the Russian Empire, Actual Privy Councillor V.V.

Accelerated Growth, Differentiation, and Ploidy with Reduced Proliferation of Right Ventricular Cardiomyocytes in Children with Congenital Heart Defect Tetralogy of Fallot.

The myocardium of children with tetralogy of Fallot (TF) undergoes hemodynamic overload and hypoxemia immediately after birth. Comparative analysis of changes in the ploidy and morphology of the right ventricular cardiomyocytes in children with TF in the first years of life demonstrated their significant increase compared with the control group. In children with TF, there was a predominantly diffuse distribution of Connexin43-containing gap junctions over the cardiomyocytes sarcolemma, which redistributed into the intercalated discs as cardiomyocytes differentiation increased.

[SCREENING ASSESSMENT OF MATERIALS THROMBOGENICITY BY THE NUMBER OF PLATELETS ADHERED FROM THE FLOWING NATIVE BLOOD].

The materials used in the construction of implants contacting with blood should be resistant to thrombus formation. One of the stages of a thrombogenicity assessment of materials is to determine the number of platelets adhered to its surface during the exposure to flowing blood under ex viAvo conditions. The aim of this study was to develop a modified test for screening assessment of materials for their thrombogenicity in contact with native blood.

[ELDERLY CARDIAC PATIENTS: SELF-REPORTED HEALTH STATUS].

Introduction: Thanks to advances in science and medicine, the threshold age of a patient who can undergo open surgery on the valves of the heart or coronary arteries is increasing every year. Elderly patients constitute a special group in this regard.

Aim: Determine how elderly cardiac patients assess their health status and highlight the factors influencing it.

The state of cognitive function in patients with stable coronary artery disease after coronary artery bypass grafting.

Aim      To study the cognitive function (CF) state in patients with chronic ischemic heart disease (IHD) depending on the method of coronary bypass (CB), with extracorporeal circulation (EC) or on beating heart.Material and methods  Postoperative cognitive dysfunction (POCD) is a frequent complication of CB, and its development may depend on the method of surgery, with EC or on beating heart. This single-center, prospective, nonrandomized study included 196 patients with chronic IHD aged 61.

[Hybrid operations in treatment of patients with multi-level lesions of lower limb arteries].

The article is a review of literature dedicated to simultaneous open and endovascular (hybrid) operations in treatment of patients with chronic ischaemia of lower limbs. Despite good results of endovascular interventions, in many situations involvement of arteries below the inguinal fold and multilevel lesions are arguments in favour of performing an open operation. On the other hand, open multilevel interventions are accompanied by an increased risk of complications and mortality.

Progressive chronic SARS-CoV-2-positive giant cell myoendocarditis with atrial standstill and sudden cardiac death.

Giant cell myocarditis (GCM) is a rare condition. Its association with SARS-CoV-2 has not been described before. The 46-year-old female patient was admitted to the clinic on September 2020.

Parameter variations in personalized electrophysiological models of human heart ventricles.

The objectives of this study were to evaluate the accuracy of personalized numerical simulations of the electrical activity in human ventricles by comparing simulated electrocardiograms (ECGs) with real patients' ECGs and analyzing the sensitivity of the model output to variations in the model parameters. We used standard 12-lead ECGs and up to 224 unipolar body-surface ECGs to record three patients with cardiac resynchronization therapy devices and three patients with focal ventricular tachycardia. Patient-tailored geometrical models of the ventricles, atria, large vessels, liver, and spine were created using computed tomography data.

[Floating structure of the carotid artery as a cause of microembolism in the basin of cerebral arteries].

This article describes a rare clinical and diagnostic case report regarding a female patient presenting with frequent transitory attacks in the basin of both middle cerebral arteries. Based on the findings of duplex scanning of the cervical arteries we revealed floating structures with the presence of pronounced slow turbulent blood flow. After excluding all known causes of cerebral artery microembolism, associated with heart pathology or with the presence of unstable atherosclerotic plaques, the leading hypothesis of transitory ischaemic attacks in the woman concerned was the formation of microthrombi in the zone of motility of the structures revealed.

International Pediatric Perfusion Practice: 2016 Survey Results.

New cardiopulmonary bypass device techniques emerge and are reported in the scientific literature. The extent to which they are actually adopted into clinical practice is not well known. Since 1989, we have periodically surveyed pediatric cardiac centers to ascertain practice patterns.

Morpho-functional changes of cardiac telocytes in isolated atrial amyloidosis in patients with atrial fibrillation.

Telocytes are interstitial cells with long, thin processes by which they contact each other and form a network in the interstitium. Myocardial remodeling of adult patients with different forms of atrial fibrillation (AF) occurs with an increase in fibrosis, age-related isolated atrial amyloidosis (IAA), cardiomyocyte hypertrophy and myolysis. This study aimed to determine the ultrastructural and immunohistochemical features of cardiac telocytes in patients with AF and AF + IAA.

Right atrial appendage aneurysm in a fetus-Does precise prenatal diagnosis matter?

Introduction: Congenital malformations of the right atrium-aneurysms and diverticulaare rare heart defects with only a few cases having been described prenatally. Early diagnosis of these anomalies is extremely important due to the possibility of such serious complications such as supraventricular arrhythmia, thromboembolic events and sudden death.

Topic Description: Although each of these anomalies is well known, there are still significant discrepancies in diagnosis.

[Clinical and organizational assessment of endovascular care accessibility at the regional level].

The world health care system´s concern of inequalities in treatment of receiving the necessary medical care. The purpose of article to evaluate the availability of endovascular care (EVC) for patients at regional level in Russia and to develop a system for its improvement. As a result the low availability of EVC for the population at the regional level in Russia with coronary heart disease, atherosclerosis of the brachiocephalic arteries and critical lower limb ischemia (CLLI) was funded.

Effectiveness of Bokeria-Boldyrev ACH Solution in Surgerical Treatment of Adult Patients with Obstructive Hypertrophic Cardiomyopathy.

The study examined effectiveness of pharmaco-cold cardioplegia employing solutions of enhanced buffer capacity during surgery of obstructive hypertrophic cardiomyopathy in adult patients (N=51) operated during 2013-2018. In group 1 (N=28), the cardioplegia was performed with HTK (Custodiol) solution, whereas in group 2 (N=23), it was carried out with Bokeria-Boldyrev ACH solution. The mean, minimum, and maximum ages in group 1 were 46, 21, and 64 years, respectively; in group 2 - 42, 14, and 70 years, respectively.

Telocytes in the Myocardium of Children with Congenital Heart Disease Tetralogy of Fallot.

Telocytes, a new type of interstitial stem cells with long thin processes that form a three-dimensional network around cardiomyocytes, vessels, and nerve fibers were described in the myocardium of children with tetralogy of Fallot. Two types of morphologically different telocytes, spindle-shaped and rounded, were identified. Contacts of telocytes with stem cells and interstitial macrophages were found.

New Technique in Assessment of Heart Chambers Remodeling in Acquired Mitral Valve Defects.

Objective: Analysis and presentation of the capabilities of the new ultrasound technique -the index of volume remodeling (IRV), which allows comprehensive assessing of pathological remodeling of the heart as an integrated functional anatomical system.

Materials And Methods: For this study 316 patients with acquired mitral valve disease (MVD) were examined prior to and following mitral valve replacement with bileaflet, disc-, and bioprostheses. Key parameters of the heart were measured in classical echocardiographic projections (end systolic area, end-diastolic area, end systolic volume, and end diastolic volume of ventricles, ventricular ejection fraction, atrial volume, and the ratio of ventricular to atrial volumes).

Composite Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma and Epstein-Barr virus-negative diffuse large B-cell lymphoma in the parotid salivary gland of a patient with Sjögren's syndrome and rheumatoid arthritis: a case report.

Background: Epstein-Barr virus is associated with many human hematopoietic neoplasms; however, Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma is extremely rare. In routine clinical practice, detection of mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma in a tissue sample presumes a clonal relation between these neoplasms and that diffuse large B-cell lymphoma developed by transformation of the mucosa-associated lymphoid tissue lymphoma. However, evidence to support this presumption is sparse and controversial.

First-trimester prediction of small-for-gestational age in pregnancies at false-positive high or intermediate risk for fetal aneuploidy.

Objectives: To explore the risk of small-for-gestational age (SGA) and fetal growth restriction (FGR) and to test the performance of first-trimester screening for SGA and FGR in women with a false-positive high or intermediate risk for aneuploidy.

Methods: This was a prospective cohort study of women with a singleton pregnancy attending for a routine first-trimester scan. The risks of aneuploidy and preterm SGA (defined as birth weight < 10 percentile with delivery before 37 weeks) were determined according to Fetal Medicine Foundation algorithms.

[Hypertrophic cardiomyopathy. Cardiomyocyte ultrastructure, the specific or stereotypic signs].

Unlabelled: Hypertrophic cardiomyopathy (HCM) is a congenital disease caused by mutations in a number of sarcomere proteins. According to the type of mutation, clinical observations record similar clinical manifestations, myocardial pathological changes, and the timing of manifestation of the disease in HCM patients.

Objective: To study cardiomyocyte (CMC) ultrastructural changes in the interventricular septum (IVS) of patients with HCM and evaluate their specificity for this pathology.