[STUDY OF THE POSITION TOWARDS HEALTH AND HEALTHY LIFESTYLE OF RAILWAY WORKERS].

Purpose: determination of the risk factors increasing the probability of development of non-communicable diseases at employees of the railway industry and also value of a condition of conditions for maintaining the healthy lifestyle by employees.

Materials And Methods: 13,595 people were interviewed (1.5% of the staff).

[Locoregional anesthesia in endoscopic surgery of intracerebral hypertensive hemangiomas].

Introduction: Currently, minimally invasive methods of surgical treatment of hypertensive intracerebral hematomas (ICHs) are actively used. However, anesthetic management of these surgeries are unclear. Moreover, advisability of locoregional anesthesia (LRA) for endoscopic aspiration of hypertensive ICHs has not been studied.

[Medical solution to needle breakage during local anesthesia].

Needle breakage may be a damaging experience for both medical practitioners and patients. Medical literature provides numerous cases of dental practitioners being confronted with this problem. We have studied the clinical case of the patient L.

State of Stress-Marker Organs in Rats after a Single Exposure to Long-Term Stress and Treatment with Lipopolysaccharide.

We studied the effect of LPS on the state of stress-marker organs in rats at various periods after a single exposure to long-term stress on the model of 24-h immobilization. The animals were intraperitoneally injected with LPS in a dose of 100 μg/kg immediately after the negative emotiogenic exposure. Changes in physiological parameters were evaluated 3 h, 1 day, and 8 days after immune stimulation.

Blood Cytokine Profile in Rats with Various Behavioral Characteristics after a Single Exposure to Long-Term Stress.

Changes in the blood cytokine profile of rats with different behavioral activity were evaluated in various periods after stress exposure on the model of 24-h immobilization. Behaviorally active animals exhibited only a tendency to a change in the concentration of study cytokines in the dynamics after experimental stress. Stress exposure in passive specimens was accompanied by a decrease in the content of pro- and anti-inflammatory cytokines.

Cellular Composition of the B- and T-Cell-Dependent Areas in the Small Intestine during the Post-Stress Period (Experimental Study).

A quantitative study of lymphoid cells in the B- and T-cell-dependent areas of intestinal lymphoid nodules and mesenteric lymph nodes in behaviorally passive and active rats was performed at various periods after acute stress on the model of 1-h immobilization with simultaneous electrocutaneous stimulation. Stress exposure is accompanied by a decrease in the number of lymphoid cells in immunogenic structures of the gastrointestinal tract. Post-stress changes in the cytoarchitectonics of B- and T-cell-dependent areas in mesenteric lymph nodes of animals are less pronounced than in lymphoid nodules.

Behavioral Indexes of Thermal Nociceptive Sensitivity in Rats after Melatonin Administration.

We studied the effect of melatonin (10 mg/kg intraperitoneally) on behavioral indexes reflecting changes in nociceptive sensitivity of rats in response to thermal stimulation in the hot plate test. Administration of melatonin to animals suppressed the perceptual component of nociception, which was manifested in an increase in the perception threshold of noxious thermal stimulus. In the follow-up period, exogenous melatonin contributed to a decrease in the latency of avoidance reactions and enhanced the behavior of escaping the thermal nociceptive stimulation.

State of Stress-Marker Organs in Rats with Various Behavioral Characteristics during Repeated Stress Exposures.

Changes in the relative weight of stress-marker organs in rats with various behavioral patterns in the open-field test were studied after repeated stress exposures on the model of daily 4-h immobilization over 8 days. Involution of the thymus and spleen in behaviorally passive specimens was found after single stress, as well as under conditions of 3- and 8-fold immobilizations. The weight of these organs in active animals remained practically unchanged after acute stress, but decreased on day 3 and particularly on day 8 of repeated stress exposures.