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A. Gemelli Hospital IRCCS[Affiliation] Publications | LitMetric

7 results match your criteria: "A. Gemelli Hospital IRCCS[Affiliation]"

Aminotransferases, particularly alanine aminotransferase (ALT), are commonly used in the detection, diagnosis, and management of chronic liver diseases. ALT, a sensitive and cost-effective marker of liver injury, remains pivotal in predicting clinical outcomes and guiding interventions in several chronic liver diseases including metabolic dysfunction-associated steatotic liver disease, and chronic viral hepatitis. This study aims to explore the evolving role of ALT as a biomarker.

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Introduction: EpiCheck is a new urinary test that analyses DNA methylation biomarkers in order to identify high-risk urothelial cancer MATERIALS AND METHODS: A prospective single centre study was performed. We analysed Epicheck results in a population of 231 patients in follow-up for non-muscle invasive bladder cancer. The primary endpoint was to evaluate sensitivity and specificity of Epicheck in detecting any type of bladder cancer recurrence.

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: Local and systemic corticosteroids have long been the workhorse in management of chronic rhinosinusitis with nasal polyps (CRSwNP), although there is no universally accepted modality of prescription. We carried out a survey in Italy to capture current trends in the use of topical and systemic corticosteroids in patients with CRSwNP. : A survey was set up on Survey Monkey.

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Article Synopsis
  • Radical cystectomy with permanent urinary diversion is the standard treatment for invasive bladder cancer, but distinguishing between obstructive and non-obstructive hydronephrosis can be challenging with traditional imaging methods like Ultrasound (US) and Computed Tomography Urography (CTU).
  • Using Diuresis Renography (DR) with the F + 10 seated method on 39 patients, researchers were able to identify those with Uretero-ileal Anastomosis Strictures (UAS), which indicated a need for surgical intervention.
  • The results revealed that DR significantly reduced diagnostic uncertainty; 36 out of 44 hydronephrotic kidneys showed obstructive findings, leading to targeted treatments for UAS and better management strategies for
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The possibility to use β decaying isotopes for radioguided surgery (RGS) has been recently proposed, and first promising tests on ex-vivo samples of Meningioma and intestinal Neuroendocrine Tumor (NET) have been published. This paper reports a study of the uptake of Ga-DOTATOC in pancreatic NETs (pNETs) in order to assess the feasibility of a new RGS approach using Y-DOTATOC. Tumor and healthy pancreas uptakes were estimated from Ga-DOTATOC PET/CT scans of 30 patients with pNETs.

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Spleen ultrasound elastography: state of the art and future directions - a systematic review.

Eur Rev Med Pharmacol Sci

May 2019

Department of Internal Medicine, Gastroenterology and Hepatology, A. Gemelli Hospital - IRCCS, Catholic University of Rome, Rome, Italy.

Objective: An early and accurate diagnosis of clinically significant portal hypertension is mandatory for a correct prediction and management of the complications usually observed in patients affected by chronic liver disease (CLD). Spleen stiffness measurement is arising as a promising non-invasive technique, giving a reliable measure of haemodynamic changes occurring during cirrhosis progression, but contrasting data are available to date.

Materials And Methods: A systematic review was performed including the several studies dealing with the spleen stiffness measurement in the evaluation of portal hypertension in adult patients affected by hepatic or extra-hepatic portal hypertension (PH).

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Background: Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age.

Case Presentation: We describe the case of a 9-year-old boy with a diagnosis of PUNLMP, who underwent to cystoscopic lesion removal and later to endoscopic lesion removal and intra-bladder Mitomycin-c (MMC) instillations for relapsed disease. Follow-up investigations at five years showed disease negativity.

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