Does menopause elevate the risk for developing depression and anxiety? Results from a systematic review.

Objective: To determine whether menopause elevates the risk for developing diagnostic depression and anxiety. Menopause-associated vasomotor symptoms such as insomnia and hot flushes are well recognized, but no systematic review of the psychological consequences of menopause has been undertaken. Menopause can be a time of social change for women, confounding any correlation.

The impact of the COVID-19 pandemic on the mental health and wellbeing of refugees and asylum seekers-A Narrative Review of the Literature.

Objective: To identify the factors affecting refugees and asylum seekers mental health and wellbeing during the COVID-19 pandemic.

Methods: A narrative review of available international research literature from January 2020 to June 2021 was conducted to identify these factors.

Results: Seven factors were identified: pre-existing physical health vulnerabilities, pre-existing mental health vulnerabilities, environmental, social, cultural-specific, economic and legal/welfare challenges.

Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.

In this study we investigated the effects of variously derived sources of low-dose caffeine on mood/arousal and cognitive performance. Twenty-two participants (15 men, 7 women; age: 28.2, 9.

Improving the mental health of Australians: A renewed call for primary care psychiatry.

Objective: To describe different ways to improve liaison between psychiatrists and general practitioners in Australia.

Conclusion: Strengthening the links between psychiatry and GPs in primary care is an effective approach to improve the mental health of Australians.

Child Sexual Abuse Prevention: Parental Discussion, Protective Practices and Attitudes.

Understanding parental practices and attitudes regarding child sexual abuse (CSA) prevention could be used to improve CSA prevention, but little information is available. In this study, we summarise survey data collected from 248 Australian and UK parents (87% female) with at least one child aged 6-11 years ( = 8.6, = 1.

Rapamycin as a potent and selective inhibitor of vascular endothelial growth factor receptor in breast carcinoma.

Angiogenesis is the process of new vascular formation, which is derived from various factors. For suppressing cancer cell growth, targeting angiogenesis is one of the therapeutic approaches. Vascular endothelial growth factor family receptors, including Flt-1, Flk-1 and Flt-4, have been found to play an essential role in regulating angiogenesis.

Decreased mobility, lack of social support, haemosiderosis and use of antidepressant medications may predict recurrent venous leg ulcers within 12 months of healing: A prospective longitudinal study.

Aim: To identify clinical, medical and psychosocial predictors of venous leg ulcer recurrence within 12 months of healing.

Methods: A multi-site study was conducted in Australia in community and hospital outpatient settings. Adults with venous leg ulcers were recruited within 4 weeks of healing and data were collected on preventative treatments and health, medical, clinical and psychosocial factors.

Investigating the Impact of OGT Inhibition on Doxorubicin- and Docetaxel-Induced Cytotoxicity in PC-3 and WPMY-1 Cells.

Reduction in sensitivity in terms of cytotoxicity is responsible for therapy failure in patients undergoing chemotherapy with first-line anticancer drug molecules. A plethora of literature evidence points out that increased -linked β--acetylglucosamine transferase (OGT) enzyme level/hyper--GlcNAcylation has direct implications in development of cancer and interferes with clinical outcomes of chemotherapy via interaction with oncogenic factors. The aim of this research was to evaluate the combination approach of anticancer drugs with an OGT inhibitor (OSMI-1) as an alternative way to resolve issues in the treatment of prostate cancer and assess the benefits offered by this approach.