19,872 results match your criteria: "900 University Avenue[Affiliation]"

Subclinical bacteriuria and surgical-site infection in 140 dogs with orthopedic and neurological conditions.

Can Vet J

December 2024

Small Animal Surgery Service, Department of Clinical Sciences (Porcel Sánchez, Gagnon, Freire), Faculty of Veterinary Medicine (Juette), University of Montreal, 3200 Rue Sicotte, Saint-Hyacinthe, Quebec J2S 2M2; Department of Clinical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1 (Brisson); Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3 (Hoddinott).

Objectives: This study aimed to determine the prevalence, risk factors, and types of bacterial isolates associated with subclinical bacteriuria (SBU) in dogs with reduced mobility; and to explore the influence of SBU on surgical-site infection (SSI) in dogs treated surgically for their conditions.

Animals: We studied 140 client-owned dogs.

Procedure: Medical records of dogs with orthopedic and neurological conditions from 3 academic referral hospitals were reviewed.

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The flowers of Hosta plantaginea (Lam.), a traditional Chinese medicine, is utilized for the treatment of sore throat, aphonia, and cough alleviation. The polysaccharides HPFP-1 and HPFP-2 were separated from these plants through water-soluble alcohol precipitation and column chromatography.

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People who approve of one's physical activity vs. people who are influential: A randomized cross-over experiment to compare normative referent elicitation procedures.

Psychol Sport Exerc

December 2024

Department of Kinesiology and Physical Education, Wilfrid Laurier University, 75 University Avenue West, Waterloo, Ontario, N2L 3C5, Canada. Electronic address:

Objectives: To compare injunctive norm scores assessed based on Ajzen's (2002) original normative referent elicitation method (e.g., norms from those who approve/disapprove of physical activity) and a revised method (e.

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Background: Leveraging the radiomics information from non-small cell lung cancer (NSCLC) primary lesion and brain metastasis (BM) to develop and validate a bimodal radiomics nomogram that can accurately predict epidermal growth factor receptor (EGFR) status.

Methods: A total of 309 NSCLC patients with BM from three independent centers were recruited. Among them, the patients of Center I were randomly allocated into the training and internal test cohorts in a 7:3 ratio.

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Compsanthias new genus is described for Anthias ventralis Randall (type species) and A. hawaiiensis Randall, which had been previously classified in the genus Pseudanthias Bleeker. Compsanthias is distinguished from other anthiadid genera in having the following combination of characters: dorsal-fin rays X,16-18, usually X,17; anal-fin rays III,9-10, usually III,9; pectoral-fin rays 14-16, usually 15, most rays branched; branched caudal-fin rays 7+6; tubed scales in lateral series 39-46.

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Implementing differential recovery corrections enhances accuracy of mass balances on microplastics in wastewater treatment.

Water Res

March 2025

Department of Civil & Environmental Engineering, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada, N2L 3G1.

This study examined the impact of using different analytical recovery practices to correct MP concentrations on the performance of count and mass balances of primary wastewater settling. Spiking tests using standard MPs were conducted to evaluate the influence of MP size and sample type on recovery. The derived recovery values were then used to correct MP concentrations and loads in a full-scale primary treatment facility.

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Article Synopsis
  • Measuring deeply virtual Compton scattering (DVCS) on the neutron is essential for understanding the nucleon's structure through generalized parton distributions (GPDs).
  • Neutron targets help complement data obtained from polarized protons, particularly in determining the poorly understood GPD E, which is crucial for analyzing quark contributions to nucleon spin.
  • The experiment utilized a longitudinally polarized electron beam at Jefferson Lab and the CLAS12 detector to measure DVCS on the neutron for the first time, providing new insights into quark-flavor separation of relevant Compton form factors.
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Discovery of peptides for ligand-mediated delivery of mRNA lipid nanoparticles to cystic fibrosis lung epithelia.

Mol Ther Nucleic Acids

December 2024

Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA.

For cystic fibrosis patients, a lung-targeted gene therapy would significantly alleviate pulmonary complications associated with morbidity and mortality. However, mucus in the airways and cell entry pose huge delivery barriers for local gene therapy. Here, we used phage display technology to select for and identify mucus- and cell-penetrating peptides against primary human bronchial epithelial cells from cystic fibrosis patients cultured at the air-liquid interface.

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Reactive carbon capture using electrochemical reactors.

Chem Soc Rev

December 2024

Department of Chemistry, The University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1, Canada.

The electrolytic upgrading of CO presents a promising strategy to mitigate global CO emissions while generating valuable carbon-based products such as carbon monoxide, formate, and ethylene. However, the adoption of industrial-scale CO electrolyzers is hindered by the high energy and capital costs associated with the purification and pressurization of captured CO prior to electrolysis. One promising solution is "reactive carbon capture," which involves the electrolytic conversion of the eluent from CO capture units, or the "reactive carbon solution," directly into valuable products.

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Background: The global public health burden of rare diseases has become an increasingly discussed topic, and its societal impact cannot be overstated. While it may seem counterintuitive to discuss broad healthcare and public health impact in the context of rarity, taken together, over 400 million people worldwide are estimated to live with a rare disease. Over half of people living with a rare disease are children.

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Background: Community-based primary health care represents various community-based health care (CBPHC) models that incorporate health promotion and community development to deliver first-contact health services. Learning health systems (LHSs) are essential for improving CBPHC in which feedback from relevant stakeholders is used to continuously improve health systems with the goal of achieving population health and health equity. Performance reporting is one way to present data to clinicians and decision makers to facilitate a process of reflection, participation, and collaboration among partners to improve CBPHC.

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A scoping review on pediatric sepsis prediction technologies in healthcare.

NPJ Digit Med

December 2024

Department of Systems Design Engineering, Faculty of Engineering, University of Waterloo, 200 University Avenue West, Waterloo, N2L3G1, Ontario, Canada.

This scoping review evaluates recent advancements in data-driven technologies for predicting non-neonatal pediatric sepsis, including artificial intelligence, machine learning, and other methodologies. Of the 27 included studies, 23 (85%) were single-center investigations, and 16 (59%) used logistic regression. Notably, 20 (74%) studies used datasets with a low prevalence of sepsis-related outcomes, with area under the receiver operating characteristic scores ranging from 0.

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Chromium isotope fractionation during the removal of hexavalent chromium by oak-based biochar.

Chemosphere

December 2024

Department of Earth and Environmental Sciences, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2N 3G1, Canada. Electronic address:

Chromium, especially in its hexavalent form (Cr(VI)), poses significant health risks due to its carcinogenic properties. Emerging research suggests that biochar, a carbon-rich material derived from biomass pyrolysis, holds promise as an effective and sustainable solution for Cr(VI) remediation. Biochar's unique physicochemical properties, such as its high surface area, porous structure, and functional groups, contribute to its exceptional adsorption capacity for metals.

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Tailoring graphitized cellulose nanocrystal morphologies for robust barrier and mechanical enhancement of PPC composites for green active packaging.

Int J Biol Macromol

January 2025

Key Laboratory of Intelligent Textile and Flexible Interconnection of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou 310018, China; Department of Chemical Engineering, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada. Electronic address:

Both nanocellulose and graphene nanosheets serve as exceptional fillers for biopolymers. However, there are limited materials that effectively combine the properties of these two fillers in Poly (propylene carbonate) (PPC) to enhance their overall properties. This study presents a meticulous approach to producing graphitized nanocellulose (GCNC) with tailored rod-like (R-GCNC) and spheres-like (S-GCNC) under low-temperature and ambient-pressure conditions.

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Reservoirs around the world have significantly altered the natural transport of nutrients in rivers. However, the specific effects of the cascade damming on the migration, transformation, and environmental consequences of these nutrients remain unclear. To address this knowledge gap, we analyzed spatiotemporal variations in water chemistry, nutrient concentrations, stable isotope of dissolved inorganic carbon (δC) and nitrate isotope (δN-NO) in seven cascade reservoirs along the Wujiang River, each characterized by different regulatory regimes.

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Background: As the population of individuals with HIV ages rapidly due to advancements in antiretroviral therapy, virtual care has become an increasingly vital component in managing their complex health needs. However, little is known about perceptions of virtual care among older adults living with HIV.

Objective: This study aimed to understand the perceptions of older adults living with HIV regarding virtual care.

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Re-evaluating the timing of sequential cranial ultrasound screening in very preterm infants for predicting neurodevelopmental outcomes.

Pediatr Radiol

December 2024

Department of Diagnostic Radiology, Division of Pediatric Radiology, Dalhousie University, IWK Health, 5850/5980 University Avenue, PO Box 9700, Halifax, NS, B3K 6R8, Canada.

Article Synopsis
  • - The objective of the study is to determine whether a model using fewer cranial ultrasounds can accurately predict neurodevelopmental impairment in very preterm infants, as current practices involve four screening points.
  • - The research analyzed data from 656 very preterm infants born between 2004 and 2018, finding that 30% of them developed neurodevelopmental impairment by 36 months of age, while comparing different prediction models based on gestational age, sex, and ultrasound timing.
  • - Results indicated that the model using the 6-week ultrasound provided the best predictive ability for neurodevelopmental impairment, though all models showed similar effectiveness according to their statistical performance measures.
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Child maltreatment mortality in Canada: An analysis of coroner and medical examiner data.

Child Abuse Negl

January 2025

Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, 785 Carling Avenue, Ottawa, ON K1A 0K9, Canada; School of Arctic and Subarctic Studies, Labrador Campus, Memorial University, 171 Hamilton River Road, Happy Valley-Goose Bay, NL A0P 1E0, Canada. Electronic address:

Article Synopsis
  • The study investigates child maltreatment fatalities in Canada, identifying cases classified as homicide or undetermined manner and estimating mortality rates by various factors.
  • Out of 1,758 child deaths analyzed, 20.4% were linked to maltreatment, primarily affecting children under 5 years old.
  • The overall national maltreatment mortality rate was found to be 0.55 per 100,000, with the highest rate among infants at 3.43 per 100,000, highlighting significant age-related disparities.
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The Role of Electron Transfer in Copper-Mediated C(sp)-H Trifluoromethylation.

Angew Chem Int Ed Engl

December 2024

Department of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH, 43210, United States.

We report copper(II) and copper(III) trifluoromethyl complexes supported by a pyridinedicarboxamide ligand (L) as a platform for investigating the role of electron transfer in C(sp)-H trifluoromethylation. While the copper(II) trifluoromethyl complex is unreactive towards (hetero)arenes, the formal copper(III) trifluoromethyl complex performs C(sp)-H trifluoromethylation of a wide range of (hetero)arenes. Mechanistic studies using the copper(III) trifluoromethyl complex suggest that the mechanism of arene trifluoromethylation is substrate-dependent.

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Article Synopsis
  • * Using single-molecule FRET (smFRET) techniques, researchers provided direct evidence of this subunit rotation mechanism, observing fluctuations in FRET that align with the proposed model.
  • * They measured rotation events in a timescale of 0.4-1.1 seconds, noting multiple recombination cycles and rapid rotation in the cleaved-DNA state without intermediate ligation during a ~25-second observation period.
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Additive manufacturing to fight cancer: Current Applications and Future Directions.

Drug Discov Today

December 2024

Pharmaceutical Engineering and 3D Printing (PharmE3D) Lab, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, A1920, Austin, TX 78712, USA; PharmE3D Lab, Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA. Electronic address:

3D printing has emerged as a powerful tool demonstrating effectiveness in early screening and targeted delivery for various types of tumors. Although the applications of additive manufacturing for cancer are widespread, the issues of scaling up, quality control and specificity remain. This review presents a comprehensive analysis of the current landscape of use of additive manufacturing in cancer diagnostics and treatment.

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Selection of Plastic-Binding DNA Aptamers for Microplastics Detection.

Angew Chem Int Ed Engl

November 2024

Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, N2L 3G1, Canada.

Article Synopsis
  • Plastics, while essential in technology, are causing environmental issues due to microplastic contamination, leading to a need for better detection methods.
  • The study focused on isolating DNA aptamers for polyvinylchloride (PVC) and polystyrene (PS), revealing that the PVC-1 aptamer binds PVC six times more effectively than random DNA sequences.
  • Utilizing a fluorescently labeled PVC-1 aptamer, the research demonstrated the ability to detect microplastics as low as 1 mg and showed selectivity over other materials, suggesting potential for environmental monitoring applications.
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Cranial motor neuron input specificity refined by activity.

Trends Neurosci

November 2024

Biology Department, Southwestern University, 1001 E. University Avenue, Georgetown, TX 78626, USA. Electronic address:

A recent study by Kaneko and colleagues provides evidence that developing cranial motor neurons in larval zebrafish refine their input specificity over time, using an activity-dependent mechanism that may depend, in part, on adaptive dendrite extension. These findings illuminate the mechanism by which spatially overlapping motor pools are recruited into distinct motor circuits.

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