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Meniscal material properties are minimally affected by matrix stabilization using glutaraldehyde and glycation with ribose.
J Orthop Res
May 2005
Noyes-Giannestras Biomechanics Laboratories, Department of Biomedical Engineering, University of Cincinnati, 893 Engineering Research Center, OH 45221-0048, USA.
Article Synopsis
- Knee meniscus replacement shows promise, but current allografts face biodegradation issues, necessitating methods like glutaraldehyde and glycation for stabilization.
- Testing on porcine meniscus revealed that while some treatments preserved key material properties, permeability significantly increased with all stabilization methods.
- Further research is needed to ensure these treatments effectively prevent degradation during and after knee surgeries without compromising the meniscus's function.