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17 results match your criteria: "8097Uppsala University[Affiliation]"
Lupus
February 2023
Division of Rheumatology, Department of Medicine Solna, Karolinska University Hospital, 27106Karolinska Institute, Stockholm, Sweden.
Background: Lupus nephritis (LN) is a major and severe organ involvement in systemic lupus erythematosus (SLE), whose diagnosis and treatment necessitate to perform kidney biopsy, which is an invasive procedure. Non-invasive urine biomarkers are an active area of investigation to support LN diagnosis and management.
Objective: To investigate the role of urinary galectin-3 binding protein (u-Gal-3BP) as a candidate biomarker of renal disease in biopsy proven LN.
Innate Immun
October 2022
Anesthesiology and Intensive Care, 174469Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Ventilator associated pneumonia (VAP) caused by is a cause of morbidity and mortality in critically ill patients. The spread of pathogens with anti-microbial resistance mandates the investigation of novel therapies. Specific polyclonal anti- IgY-antibodies (IgY) might be effective for VAP caused by The objective of this study was to investigate if intravenous IgY decreases the lower airway concentration of in VAP.
View Article and Find Full Text PDFBackground: Despite its negative impact on patients and nurses, the use of restraint in somatic health care continues in many settings. Understanding the reasons and justifications for the use of restraint among nurses is crucial in order to manage this challenge.
Aim: To understand nurses' justifications for restraint use in neurosurgical care.
Nurs Ethics
August 2022
Faculty of Health and Life Sciences, 6140Linnaeus University, Växjö, Sweden; Centre of Interprofessional Collaboration within Emergency care (CICE), Linnaeus University, Växjö, Sweden.
Background: Older patients in emergency care often have complex needs and may have limited ability to make their voices heard. Hence, there are ethical challenges for healthcare professionals in establishing a trustful relationship to determine the patient's preferences and then decide and act based on these preferences. With this comes further challenges regarding how the patient's autonomy can be protected and promoted.
View Article and Find Full Text PDFJ Empir Res Hum Res Ethics
October 2022
12264University of Maryland School of Medicine, Baltimore, Maryland, USA.
Lately, there has been increased research performed in Egypt. In response, the Egyptian Parliament published its first clinical research law in December 2020. The official version of the law was translated to English from Arabic and back by an accredited translation service.
View Article and Find Full Text PDFJ Pediatr Hematol Oncol Nurs
April 2022
7643Ersta Sköndal Bräcke University College, Department of Health Care Sciences, Palliative Research Centre, Stockholm, Sweden.
There are few scientifically evaluated psychosocial interventions in pediatric oncology, despite the needs for families. The family-based psychosocial intervention "The Family Talk Intervention" (FTI) has shown promising results in other care contexts and was therefore pilot-tested in pediatric oncology. In this study, we examined the experiences of participating in FTI from ill children's perspectives regarding feasibility and potential effects.
View Article and Find Full Text PDFHealth Informatics J
April 2022
Department of Public Health and Caring Sciences, 8097Uppsala University, Uppsala, Sweden.
Studies on use of IT in residential care are limited; thus, there is a need for investigations to understand both older people's and nursing staff's perspectives on experiences of new technology. 'Smart homes' provide home automation solutions, making life easier for those residing there. The aim was to explore, from the users' perspective, experiences of a sensor system installed in the home.
View Article and Find Full Text PDFJ Intensive Care Med
November 2022
8097Uppsala University, Uppsala, Sweden.
Background: In this study, the association of the arterial content of oxygen, carbon dioxide, glucose, and lactate with cerebral pressure reactivity, energy metabolism and clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH) was investigated.
Methods: In this retrospective study, 60 patients with aSAH, treated at the neurointensive care (NIC), Uppsala University Hospital, Sweden, between 2016 and 2021 with arterial blood gas (ABG), intracranial pressure, and cerebral microdialysis (MD) monitoring were included. The first 10 days were divided into an early phase (day 1 to 3) and a vasospasm phase (day 4 to 10).
Innate Immun
January 2022
Department of Medical Sciences, 8097Uppsala University, Uppsala, Sweden.
Calprotectin is one of the most abundant proteins of neutrophil granulocytes. It is released upon neutrophil activation and is considered a sensitive and clinically useful marker for neutrophil-mediated inflammation, including bacterial infections. However, early kinetics of calprotectin activation following inflammatory activation has hitherto been unknown.
View Article and Find Full Text PDFJ Pastoral Care Counsel
March 2022
Department of Sociology, 8097Uppsala University, Uppsala, Sweden.
Chaplain leadership may have played a pivotal role in shaping chaplains' roles in health care amidst the COVID-19 pandemic. We convened an international expert panel to identify expert perception on key chaplain leadership factors. Six leadership themes of professional confidence, engaging and trust-building with executives, decision-making, innovation and creativity, building integrative and trusting connections with colleagues, and promoting cultural competencies emerged as central to determining chaplains' integration, perceived value, and contributions during the pandemic.
View Article and Find Full Text PDFDementia (London)
April 2022
Department of Sociology, Center for Social Work (CESAR), 8097Uppsala University, Uppsala, Sweden.
The general approach to a life with dementia is negatively charged, and alternative views are rarely found in research or in media coverage. This case-study explores conversational practices for framing dementia in a more positive light, employed by a husband of a wife with dementia. Framing regards the structured experiences of dementia, drawing on Goffman's 'Frame Analysis'.
View Article and Find Full Text PDFActa Radiol
October 2022
Department of Surgical Sciences - Radiology, 8097Uppsala University, Uppsala, Sweden.
Background: When performing computed tomography (CT)-guided biopsy procedures with non-disposable, automatic biopsy instruments, the actual course of the biopsy needle is not registered.
Purpose: To evaluate the ability to visualize the sampling location after CT-guided biopsy in vitro using a novel method, where the space between the inner needle and the outer cannula in a core biopsy needle is filled with contrast media; and to compare the grade of visibility for two different concentrations of contrast media.
Material And Methods: Core needle biopsies were performed in a tissue phantom using biopsy needles primed with two different iodine contrast media concentrations (140 mg I/mL and 400 mg I/mL).
Acta Radiol
October 2022
Department of Surgical Sciences, Section of Radiology, 8097Uppsala University, Uppsala, Sweden.
Background: Tumor response and survival varies in patients treated with transarterial chemoembolization (TACE) for intermediate stage hepatocellular carcinoma (HCC) and may be associated with several factors.
Purpose: To evaluate safety and efficacy of TACE in patients with intermediate stage HCC and to identify factors related to tumor response and survival.
Material And Methods: Consecutive patients with HCC treated with TACE between September 2008 and September 2018 were retrospectively reviewed.
Am J Hosp Palliat Care
January 2022
Department of Health Care Sciences, Ersta Sköndal Bräcke University College, Palliative Research Centre, Stockholm, Sweden.
Aim: To describe healthcare professionals' and volunteers' experiences of a pathway for movement on a hospice ward.
Method: This was a qualitative study with an inductive approach. Data were collected in a hospice setting through 4 focus group interviews with healthcare professionals and volunteers (n = 12).
Nurs Ethics
August 2021
211737Ersta Sköndal Bräcke University College, Sweden; Uppsala University, Sweden.
Background: Predatory publishing poses a fundamental threat to the development of nursing knowledge. Previous research has suggested that authors of papers published in predatory journals are mainly inexperienced researchers from low- and middle-income countries. Less attention has been paid to contributors from high-income countries.
View Article and Find Full Text PDFJ Intensive Care Med
September 2021
Department of Neuroscience, Section of Neurosurgery, 8097Uppsala University, Uppsala, Sweden.
Background: Ischemic and hypoxic secondary brain insults are common and detrimental in traumatic brain injury (TBI). Treatment aims to maintain an adequate cerebral blood flow with sufficient arterial oxygen content. It has been suggested that arterial hyperoxia may be beneficial to the injured brain to compensate for cerebral ischemia, overcome diffusion barriers, and improve mitochondrial function.
View Article and Find Full Text PDFJ Intellect Disabil
June 2021
8097Uppsala University, Sweden.
Promoting healthier lifestyles in people with intellectual disabilities is important in order to improve health and reduce health inequalities. Few studies have explored how health-promotion interventions for people with intellectual disabilities in community-based settings are experienced. The aim of this study was to explore residents', staff members' and rehabilitation professionals' experiences of how a health-promotion intervention affected the habits of people living in a group home regarding eating habits and physical activities and staffs' ways of working.
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