Nitrogen-to-functionalized carbon atom transmutation of pyridine.

The targeted and selective replacement of a single atom in an aromatic system represents a powerful strategy for the rapid interconversion of molecular scaffolds. Herein, we report a pyridine-to-benzene transformation nitrogen-to-carbon skeletal editing. This approach proceeds a sequence of pyridine ring-opening, imine hydrolysis, olefination, electrocyclization, and aromatization to achieve the desired transmutation.

γ-Amino Alcohols via Energy Transfer Enabled Brook Rearrangement.

In the long-standing quest to synthesize fundamental building blocks with key functional group motifs, photochemistry in the recent past has comprehensively established its attractiveness. Amino alcohols are not only functionally diverse but are ubiquitous in the biologically active realm of compounds. We developed bench-stable bifunctional reagents that could then access the sparsely reported γ-amino alcohols directly from feedstock alkenes through energy transfer (EnT) photocatalysis.

Impact of road transport system on groundwater quality inferred from explainable artificial intelligence (XAI).

Road networks constitute a vital component of modern society, facilitating rapid transportation and driving economic activities by enabling the smooth movement of goods and people. However, the expansion of road systems carries significant environmental considerations, particularly regarding its impact on groundwater quality. Thus, it is crucial to understand the complex relationship between groundwater quality and the road traffic system.

The effect of student engagement strategies in online instruction for data management skills.

Evaluating the effectiveness of teaching methods for synchronous online instruction is integral to fostering student engagement and maximizing student learning, particularly in one-time workshops or seminars. Using the lens of social constructivism theory, this study investigated the effect of different approaches of synchronous online instruction on the development of graduate students' research data management (RDM) skills during the post-pandemic era. One experimental group received teacher-centered instruction primarily via lecture and the second experimental group received student-centered instruction with active learning activities.

Endocrine disruptors and endometriosis.

Endometriosis is a hormone-dependent inflammatory gynecological disease of reproductive-age women. It is clinically and pathologically characterized by the presence of functional endometrium as heterogeneous lesions outside the uterine cavity. The two major symptoms are chronic pelvic pain and infertility, which profoundly affect women's reproductive health and quality of life.

SHIFTING POWERS IN SPIVEY'S BELL NUMBER FORMULA.

In this paper, we consider extensions of Spivey's Bell number formula wherein the argument of the polynomial factor is translated by an arbitrary amount. This idea is applied more generally to the -Whitney numbers of the second kind, denoted by (), where some new identities are found by means of algebraic and combinatorial arguments. The former makes use of infinite series manipulations and Dobinski-like formulas satisfied by (), whereas the latter considers distributions of certain statistics on the underlying enumerated class of set partitions.

Circadian Gene Selection for Time-to-event Phenotype by Integrating CNV and RNAseq Data.

Background: The endogenous circadian clock, which controls daily rhythms in the expression of at least half of the mammalian genome, has a major influence on cell physiology. Consequently, disruption of the circadian system is associated with wide range of diseases including cancer. While several circadian clock genes have been associated with cancer progression, little is known about the survival when two or more platforms are considered together.

Effect of moisture content on greenhouse gas and NH emissions from pig manure converted by black soldier fly.

The effects of different moisture contents on greenhouse gas (GHG) emissions from pig manure (PM) digested by black soldier fly larvae (BSFL) as well as the accompanying changes of nitrogen and carbon contents in gaseous emissions and residues were studied. A mixture of PM and corncob at the ratio of 2.2:1 was prepared with a moisture content of 45%.

Power-scalable subcycle pulses from laser filaments.

Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal physical principles. With the ratio P/P of the peak power of an ultrashort laser pulse, P, to the critical power of self-focusing, P, playing the role of the fundamental number-of-particles integral of motion of the nonlinear Schrödinger equation, keeping this ratio constant is a key principle for the power scaling of laser-induced filamentation.

Porous media properties of reticulated shape memory polymer foams and mock embolic coils for aneurysm treatment.

Background: Shape memory polymer (SMP) foams are being investigated as an alternative aneurysm treatment method to embolic coils. The goal of both techniques is the reduction of blood flow into the aneurysm and the subsequent formation of a stable thrombus, which prevents future aneurysm rupture. The purpose of this study is to experimentally determine the parameters, permeability and form factor, which are related to the flow resistance imposed by both media when subjected to a pressure gradient.