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Investigation of the solvent-dependent photolysis of a nonnucleoside reverse-transcriptase inhibitor, antiviral agent efavirenz.
Antivir Chem Chemother
December 2017
Department of Chemistry, Faculty of Natural Sciences, 70688 Mangosuthu University of Technology, Durban, South Africa.
This study sought to investigate the solvent-dependency on the photolysis of efavirenz to gain insight into the photoprocesses involved. The primary mechanisms were firstly the excited-state intramolecular proton transfer (i.e.
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