3 results match your criteria: "70399University of Saskatchewan[Affiliation]"
Vaginal microbiota associated with oncogenic HPV in a cohort of HPV-vaccinated women living with HIV.
Int J STD AIDS
August 2022
Department of Obstetrics and Gynecology, 198113University of British Columbia, Vancouver, BC, Canada.
Background: Women living with HIV (WLWH) experience higher rates of human papillomavirus (HPV) infection and cervical cancer than women without HIV. Changes in the vaginal microbiome have been implicated in HPV-related disease processes such as persistence of high-risk HPV infection but this has not been well defined in a population living with HIV.
Methods: Four hundred and 20 girls and WLWH, age ≥9, across 14 clinical sites in Canada were enrolled to receive three doses of quadrivalent HPV vaccine for assessment of vaccine immunogenicity.
Reproductive fitness of honey bee queens exposed to thiamethoxam during development.
Vet Pathol
November 2021
70399University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Article Synopsis
- Honey bee colony productivity relies on queen health, which can be negatively impacted by neonicotinoid exposure, potentially due to direct toxicity or poor care from affected worker bees.
- The study tested the effects of incremental doses of the neonicotinoid thiamethoxam (THI) on honey bee queens, finding that exposure reduced the size of their mandibular glands and subsequently may affect their ability to produce pheromones.
- Additionally, exposure to THI led to decreased larval and pupal survival and lower sperm viability, potentially hindering queen development and reproductive longevity.
Prevalence and Prognostic Impact of Papillomavirus Type 2 Infection in Equine Squamous Cell Carcinomas in Western Canadian Horses.
Vet Pathol
September 2020
70399University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
papillomavirus type-2 (EcPV-2) has been proposed as a causal factor in equine genital squamous cell carcinoma (SCC). This study had 2 objectives: first, calculate the frequency of papillomavirus (PV) and EcPV-2 infection in papillomas, carcinomas in situ (CIS), and SCCs in Western Canadian horses; and second, determine if EcPV-2 status of equine SCCs is associated with overall survival (OS). EcPV-2 status of 115 archived tissue samples, spanning 6 years, was determined using broad spectrum (MY09/11) and EcPV-2-specific polymerase chain reaction (PCR) assays, EcPV-2-E6/E7 chromogenic RNA in situ hybridization (R-ISH), and amplicon sequencing.
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