Research on the application effect of self-transcendence nursing model in patients with gestational diabetes mellitus: a randomised controlled trial.

Background: Gestational diabetes mellitus is hyperglycemia in special populations (pregnant women), however gestational diabetes mellitus (GDM) not only affects maternal health, but also has profound effects on offspring health. The prevalence of gestational diabetes in my country is gradually increasing.

Objective: To study the application effect of self-transcendence nursing model in GDM patients.

Pilot work of the 10K Chinese People Genomic Diversity Project along the Silk Road suggests a complex east-west admixture landscape and biological adaptations.

Genomic sources from China are underrepresented in the population-specific reference database. We performed whole-genome sequencing or genome-wide genotyping on 1,207 individuals from four linguistically diverse groups (1,081 Sinitic, 56 Mongolic, 40 Turkic, and 30 Tibeto-Burman people) living in North China included in the 10K Chinese People Genomic Diversity Project (10K_CPGDP) to characterize the genetic architecture and adaptative history of ethnic groups in the Silk Road Region of China. We observed a population split between Northwest Chinese minorities (NWCMs) and Han Chinese since the Upper Paleolithic and later Neolithic genetic differentiation within NWCMs.

Studies of Thermal Conductivity of Graphite Foil-Based Composite Materials.

We have proposed and developed a method for measuring the thermal conductivity of highly efficient thermal conductors. The measurement method was tested on pure metals with high thermal conductivity coefficients: aluminum (99.999 wt.

Accelerated Method for Determining the Fatigue Limit of Trabecular Bone.

This paper presents an experimental method for estimating the fatigue limit of trabecular bone using a single trabecular bone sample, the microstructural parameters of which were determined by microCT. Fatigue tests were carried out using the Locati method, with stepwise increasing load amplitude. The fatigue limits of the trabecular structures were determined experimentally in accordance with Miner's law of fatigue damage accumulation, based on the parameters of the reference S-N curve taken from the literature.

Evaluating the Quality of Real-World Data on Adherence to Oral Endocrine Therapy in Breast Cancer Patients: How Real Is Real-World Data?

Purpose: The aim of this study was to compare estimates of adherence to oral endocrine therapy (OET) based on real-world data (RWD) and on clinical evaluation in people diagnosed with breast cancer in the public healthcare system in Catalonia (Spain).

Methods: We conducted two retrospective cohort studies. Cohort 1 (RWD) consisted of women diagnosed with breast cancer in 2021 in the public healthcare system of Catalonia (Spain).

COVID-19-Related Discontinuation Impact on Patient-Reported Outcomes in Long-Term Thermal Therapy: A Single-Center Observational Study at Saturnia Thermal Springs.

Background: Thermal therapy represents a well-established therapeutic approach for chronic musculoskeletal and respiratory conditions. To date, no studies have investigated the clinical effects of treatment interruption in thermal medicine. We aimed to evaluate the clinical impact of COVID-19 lockdown-induced thermal therapy discontinuation through validated patient-reported outcomes.

Dose-dependent association of hyperoxia and decreased favorable outcomes in mechanically ventilated patients with traumatic brain injury, a retrospective cohort study.

Purpose: In patients with traumatic brain injury (TBI), adequate oxygenation is crucial to optimize survival and neurological outcome. However, supranormal oxygen partial pressure (PaO) only leads to minor increase in cerebral oxygen delivery but can cause numerous pathophysiological disturbances. Therefore, we aimed to study effects of hyperoxia on patient outcome and identify optimum PaO ranges.

Prenatal depression and child developmental vulnerability.

Background: Prenatal depression is a potentially important fetal exposure as it may alter fetal development and have lasting effects.

Methods: We examined all live births from 2001 to 2012 in British Columbia with follow-up data on the Early Development Instrument (EDI) in Kindergarten. The odds of developmental vulnerability on EDI domains among those with and without depression during pregnancy were estimated.

Duration in Immigration Detention and Health Harms.

Importance: Length of custody is a mechanism by which carceral systems can worsen health. However, there are fewer studies examining US immigration detention, in large part because US immigration detention is largely privately operated and opaque by design.

Objectives: To examine the association between duration spent in US immigration detention with subsequent health outcomes.

Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study.

Background And Objectives: Colorectal cancer is a major contributor to global cancer morbidity and mortality. Surgical resection remains the cornerstone of treatment, but postoperative complications can significantly affect patient outcomes. Identifying factors that influence postoperative morbidity and mortality is crucial for optimizing patient care.

The Carnivoran Adaptive Landscape Reveals Trade-offs among Functional Traits in the Skull, Appendicular, and Axial Skeleton.

Analyses of form-function relationships are widely used to understand links between morphology, ecology, and adaptation across macroevolutionary scales. However, few have investigated functional trade-offs and covariance within and between the skull, limbs, and vertebral column simultaneously. In this study, we investigated the adaptive landscape of skeletal form and function in carnivorans to test how functional trade-offs among these skeletal regions contribute to ecological adaptations and the topology of the landscape.

A national survey on Thai medical students' attitudes towards abortion and their confidence in providing abortion services following the amendment to abortion law.

Objectives: This study aimed to evaluate medical students' attitudes towards abortion and their confidence in providing abortion services in the future.

Material And Methods: A national cross-sectional online survey was conducted among fifth and sixth-year medical students from 10 Thai universities. A self-administered questionnaire assessed their knowledge, attitudes, and confidence regarding abortion services.

Preventing Underage Tobacco Access: A Cross-Sectional Study of Retailer Training in Southern Illinois.

. Stringent regulations restricting tobacco access to those under 21 are in place, yet young people continue accessing tobacco products. This study aimed to assess the knowledge, opinions, resource utilization, and training needs of tobacco retailers in terms of preventing underage tobacco sales.

Motivations for a career in teaching: medical students' projections towards their future role.

Background: Medical educators play a crucial role in the perpetuation of the medical profession. Recent concerns have arisen regarding the quality and quantity of current teachers. To comprehend this shortage, it is key to understand future physicians' attitudes towards venturing in education, their motivations and possible detracting factors.

Students' attitudes toward euthanasia and abortion: a cross-cultural study in three Mediterranean countries.

Introduction: Abortion and euthanasia are still one of the greatest bioethical challenges. Previous studies have shown that there are differences in attitudes towards these issues depending on socio-demographic characteristics and socio-cultural environment (country of residence). As part of the scientific research project EuroBioMed, we compared the attitudes of students from three Mediterranean countries towards abortion and euthanasia and examined them from the perspective of Mediterranean bioethics.

Differences in influenza testing and treatment in micropolitan versus metropolitan areas in the U.S. using medicare claims data from 2010 to 2016.

Background: To improve understanding of influenza and rurality, we investigated differences in influenza testing and anti-viral treatment rates between micropolitan (muSAs) and metropolitan statistical areas (MSAs) using national medical claims data over multiple influenza seasons.

Methods: Using billing data from the Centers for Medicare and Medicaid Services for those aged 65 years and older, we estimated weekly rates of ordered rapid influenza diagnostic tests (RIDT) and antivirals (AV) among Medicare enrollees by core-based statistical areas (CBSAs) during 2010-2016. We used Negative Binomial generalized mixed models to estimate adjusted rate ratios (aRR) between MSAs and muSAs, adjusting for clustering by CBSA plus explanatory variables.

A Comprehensive Modeling of Microplastic Emission from Wastewater Treatment Plants to the Sea via Rivers in China.

Wastewater treatment plants (WWTPs) are significant sources of microplastic (MP) emissions. In order to quantify the potential MP emission from WWTPs, a database of more than 10,000 WWTPs in China with an estimated MP emission rate was built. The MP riverine retention after emission was also estimated based on Stokes' law for both fragments and fibers.

Support for and likely impacts of endgame measures in the Smokefree Aotearoa Action Plan: findings from the 2020-2021 International Tobacco Control New Zealand (EASE) surveys.

Aim: In February 2024, the Aotearoa New Zealand Government repealed legislation to mandate very low nicotine cigarettes (VLNCs), greatly reduce the number of tobacco retailers and disallow sale of tobacco products to people born after 2008 (smokefree generation). We investigated acceptability and likely impacts of these measures among people who smoke or who recently (≤2 years) quit smoking.

Method: We analysed data from 1,230 participants from Wave 3 (conducted in late 2020 and early 2021) and 615 participants from Wave 3.

Characteristics influencing COVID-19 testing and vaccination among Spanish-speaking Latine persons in North Carolina.

Background: Latine populations in the United States continue to be disproportionately affected by COVID-19 with high rates of infection and mortality. Our community-based participatory research partnership examined factors associated with COVID-19 testing and vaccination within a particularly hidden, underserved, and vulnerable population: Spanish-speaking Latines.

Methods: In 2023, native Spanish-speaking Latine interviewers conducted phone-based structured individual assessments with 180 Spanish-speaking, predominantly immigrant Latines across North Carolina.

Occupational histories in neuropathologically confirmed multiple system atrophy.

Purpose: This study examined occupational histories in multiple system atrophy to identify environmental associations of potential relevance to disease causation.

Methods: A total of 270 neuropathologically confirmed cases of multiple system atrophy obtained from the Mayo Clinic Brain Bank for neurodegenerative disorders in Jacksonville, Florida, were included in this case-control study. Demographic and disease information was collected from medical records.

Long-term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the ALLEGRO-LT phase 3, open-label study.

Background: ALLEGRO-LT is an ongoing, long-term, open-label, multicentre, phase 3 study of ritlecitinib in adults and adolescents with alopecia areata (AA).

Objectives: To evaluate ritlecitinib safety and efficacy through Month 24 in patients with AA and ≥25% scalp hair loss.

Methods: ALLEGRO-LT enrolled rollover patients who previously received study intervention in either ALLEGRO phase 2a or 2b/3 studies and de novo patients who had not received treatment in either study.

Safety of combined drug use in patients with cardiovascular and cerebrovascular diseases: an analysis based on the spontaneous reporting database of adverse drug reactions in Hubei Province.

Objective: There is a lack of studies investigating the safety of combination regimens specifically for cardiovascular and cerebrovascular diseases. This study aimed to evaluate the safety of combination drugs for cardiovascular and cerebrovascular diseases using real-world data.

Methods: We analyzed adverse drug reaction data received by the Hubei Adverse Drug Reaction Center from the first quarter of 2014 to the fourth quarter of 2022.

Compliance with research participant protection guidelines by Nigerian medical journals.

Background: Stakeholders in medical research have roles in ensuring that research participants are protected. Medical journals play gatekeeping roles in the responsible conduct of research. They help guard against the publication of findings of unethical research, such as those with compromised participant welfare.

Effect of different clay additions to concrete on its ultrasonic acoustic parameters and compressive strength.

Due to various factors, the concrete may contain mud, a condition that can lead to a decrease in strength and changes in the ultrasonic acoustic parameters of the concrete. In order to study the effect of concrete mud content ([Formula: see text]) on ultrasonic acoustic parameters and compressive strength, this paper firstly derived the relationship equations between concrete mud content and acoustic parameters and compressive strength. Subsequently, the acoustic parameters and compressive strength were tested for concrete specimens with different mud contents cast on site.

Countering AI-powered disinformation through national regulation: learning from the case of Ukraine.

Advances in the use of AI have led to the emergence of a greater variety of forms disinformation can take and channels for its proliferation. In this context, the future of legal mechanisms to address AI-powered disinformation remains to be determined. Additional complexity for legislators working in the field arises from the need to harmonize national legal frameworks of democratic states with the need for regulation of potentially dangerous digital content.