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Evaluation of copeptin in children after stimulation with clonidine or L-Dopa.
J Pediatr Endocrinol Metab
May 2024
Department of Pediatrics, Division of Endocrinology, Medical School, 69182 University of Patras, Patras, Greece.
Objectives: Arginine-stimulated serum copeptin has been proposed as a new method to diagnose arginine vasopressin (AVP) deficiency in children and adolescents. Herein we investigated the secretagogic potential of clonidine or L-Dopa on the copeptin serum levels in children.
Methods: Eight stimulation tests (4 with clonidine and 4 with L-Dopa) were performed in eight children (5 boys and 3 girls) with a median age of 6.