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Inhibition of spinal MAPKs by scorpion venom peptide BmK AGAP produces a sensory-specific analgesic effect.
Mol Pain
October 2018
1 Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, 66478 Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Background Several studies have shown that scorpion venom peptide BmK AGAP has an analgesic activity. Our previous study also demonstrated that intraplantar injection of BmK AGAP ameliorates formalin-induced spontaneous nociceptive behavior. However, the effect of intrathecal injection of BmK AGAP on nociceptive processing is poorly understood.
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