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Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin.

Gynecol Oncol

May 2014

Department of Obstetrics & Gynecology, University of Toronto, Division of Gynecologic Oncology, Princess Margaret Hospital/University Health Network, 610 University Ave M 700, Toronto, Ontario M5G 2M9, Canada. Electronic address:

Objective: Oral progestin is an alternative to hysterectomy for women with complex atypical hyperplasia (CAH) or grade one endometrial cancer (G1EC) who wish fertility preservation. We evaluated treatment efficacy and fertility outcomes in this population.

Methods: Women <45 y treated with oral progestin for CAH or G1EC were identified from two cancer centers.

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