184 results match your criteria: "585 University Ave.[Affiliation]"
Ann Thorac Surg
December 2020
Poznan University of Medical Sciences, HCP Medical Center, Poznań, Poland.
J Clin Monit Comput
February 2021
Department of Anesthesia and Pain Management, Toronto General Hospital, UHN, Toronto, Canada.
Zero-heat-flux thermometers provide clinicians with the ability to continuously and non-invasively monitor body temperature. These devices are increasingly being used to substitute for more invasive core temperature measurements during surgery and in critical care. The aim of this review was to determine the accuracy and precision of zero-heat-flux temperature measurements from the 3M™ Bair Hugger™ Temperature Monitoring System.
View Article and Find Full Text PDFDig Dis Sci
February 2021
Division of Gastroenterology and Hepatology, Department of Medicine, University of California San Francisco, Zuckerberg San Francisco General Hospital, 1001 Potrero Ave., Building 5, Suite 3D, Ward 3D-4, San Francisco, CA, 94110, USA.
Background: A greater understanding of the determinants of health behavior among those with and at-risk of chronic hepatitis B virus (HBV) infection is needed for effective design and implementation of public health initiatives.
Aims: To determine factors associated with (1) willingness to accept HBV antiviral treatment and (2) satisfaction with provider communication regarding HBV care in a diverse cohort of HBV-infected patients.
Methods: Using a multifaceted model of health behavior, the Health Behavior Framework, we conducted a comprehensive assessment of knowledge, attitudes, beliefs, and barriers to HBV care.
Diabetologia
June 2020
Pfizer Inc., Andover, MA, USA.
Aims/hypothesis: This study aimed to evaluate the effect of ertugliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on eGFR and albuminuria (urine albumin/creatinine ratio [UACR]) vs glimepiride or placebo/glimepiride (non-ertugliflozin) over 104 weeks of treatment in participants with type 2 diabetes mellitus, using pooled data from two randomised controlled, active comparator studies from the eValuation of ERTugliflozin effIcacy and Safety (VERTIS) programme (Clinicaltrials.gov NCT01999218 [VERTIS SU] and NCT02033889 [VERTIS MET]). In the VERTIS SU study, ertugliflozin was evaluated vs glimepiride over 104 weeks.
View Article and Find Full Text PDFAJR Am J Roentgenol
June 2020
Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital and Women's College Hospital, University of Toronto, 585 University Ave, Toronto, ON M5G 2N2, Canada.
CT or MRI is most commonly used for characterizing focal hepatic lesions. However, findings on CT and MRI are occasionally indeterminate. Contrast-enhanced ultrasound (CEUS), with its unique characteristics as a purely intravascular contrast agent and real-time evaluation of enhancement, is a useful next step.
View Article and Find Full Text PDFEur Radiol
July 2020
Joint Department of Medical Imaging, University Health Network, Mt. Sinai & WCH, University of Toronto, 610 University Ave., 3-957, Toronto, ON, M5G 2M9, Canada.
Objectives: To compare biliary stricture severity on magnetic resonance cholangiopancreatography (MRCP), magnetic resonance elastography (MRE), and vibration-controlled transient elastography (VCTE) liver stiffness (LS) for evaluation of risk stratification and prognostication in primary sclerosing cholangitis (PSC).
Materials And Methods: Eighty-seven patients (31-61 years; 34 female/53 male) prospectively underwent biochemical testing, VCTE, MRCP, and MRE between January 2014 and July 2016. Correlation between the MRCP grading of PSC based on biliary stricture severity, LS on MRE and VCTE, and the Mayo Risk Score as well as the Amsterdam Oxford Prognostic Index (AOPI) were evaluated and compared.
Spine J
June 2020
Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada M5G 2N2; The Dalglish Family 22q Clinic for Adults, University Health Network, 200 Elizabeth St, Toronto, ON, Canada; Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, 585 University Ave, Toronto, ON, Canada M5G 2N2; Division of Cardiology, Department of Medicine, University Health Network, Toronto, ON, Canada; Toronto General Research Institute and Campbell Family Mental Health Research Institute, Toronto, ON, Canada. Electronic address:
Background Context: For over four decades, clinicians and researchers have suggested a relationship between congenital heart disease (CHD) and scoliosis, attributed to either the disease itself or to the long-term effects of cardiac surgery on the immature thoracic cage. However, no study has yet accounted for 22q11.2 deletion syndrome (22q11.
View Article and Find Full Text PDFAbdom Radiol (NY)
March 2020
Joint Department of Medical Imaging, Mount Sinai Hospital, University of Toronto, 600 University Ave., Toronto, ON, M5G 1X5, Canada.
Unfortunately the article was published with a spell error in the co-author name "Hassan Maan". The correct co-author name should be "Hassaan Maan".
View Article and Find Full Text PDFCrit Care
November 2019
Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.
Background: Excessive respiratory muscle effort during mechanical ventilation may cause patient self-inflicted lung injury and load-induced diaphragm myotrauma, but there are no non-invasive methods to reliably detect elevated transpulmonary driving pressure and elevated respiratory muscle effort during assisted ventilation. We hypothesized that the swing in airway pressure generated by respiratory muscle effort under assisted ventilation when the airway is briefly occluded (ΔP) could be used as a highly feasible non-invasive technique to screen for these conditions.
Methods: Respiratory muscle pressure (P), dynamic transpulmonary driving pressure (ΔP, the difference between peak and end-expiratory transpulmonary pressure), and ΔP were measured daily in mechanically ventilated patients in two ICUs in Toronto, Canada.
Radiology
January 2020
From the Toronto Joint Department of Medical Imaging, Toronto General Hospital, Peter Munk Cardiac Centre, University Health Network, University of Toronto, 585 University Ave, 1 PMB-298, Toronto, ON, Canada M5G 2N2 (K.H., G.R.K., R.M.W.); Fred A. Litwin Centre in Genetic Medicine, University Health Network & Mount Sinai Hospital, University of Toronto, Toronto, Canada (S.W., C.F.M.); and Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Canada (R.M.W., R.M.I.).
Background Cardiac involvement is the leading cause of mortality in patients with Fabry disease. Identification of imaging findings that predict adverse cardiac events is needed to enable identification of high-risk patients. Purpose To establish the prognostic value of cardiac MRI findings in men and women with Fabry disease.
View Article and Find Full Text PDFRadiology
October 2019
From the Toronto Joint Department of Medical Imaging, Toronto General Hospital, University Health Network, University of Toronto, 585 University Ave, 1PMB-298, Toronto, ON, Canada M5G 2N2.
Intensive Care Med
September 2019
Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.
Purpose: To describe the variability and determinants of the effect of extracorporeal CO removal (ECCOR) on tidal volume (V), driving pressure (ΔP), and mechanical power (Power) and to determine whether highly responsive patients can be identified for the purpose of predictive enrichment in ECCOR trial design.
Methods: Using data from the SUPERNOVA trial (95 patients with early moderate acute respiratory distress syndrome), the independent effects of alveolar dead space fraction (ADF), respiratory system compliance (Crs), hypoxemia (PaO/FiO), and device performance (higher vs lower CO extraction) on the magnitude of reduction in V, ΔP, and Power permitted by ECCOR were assessed by linear regression. Predicted and observed changes in ΔP were compared by Bland-Altman analysis.
J Cardiovasc Magn Reson
August 2019
Toronto Joint Department of Medical Imaging, Toronto General Hospital, University of Toronto, 585 University Avenue, 1PMB-298, Toronto, ON, M5G 2N2, Canada.
Background: Cardiac involvement is common and is the leading cause of mortality in Fabry disease (FD). We explored the association between cardiovascular magnetic resonance (CMR) myocardial strain, T1 mapping, late gadolinium enhancement (LGE) and left ventricular hypertrophy (LVH) in patients with FD.
Methods: In this prospective study, 38 FD patients (45.
J Cancer Educ
October 2020
Cancer Education Program, Princess Margaret Cancer Centre, 585 University Ave, Munk Building B-PMB 130, Toronto, Ontario, M5G 2M9, Canada.
Continued smoking at the time of a cancer diagnosis can severely impact the efficacy of cancer patient treatment and survival. The time of diagnosis can serve as a "teachable moment" for smoking cessation education, since patients may be receptive to discussions about quitting. Caregivers may have a pivotal role in supporting patients with their cessation efforts.
View Article and Find Full Text PDFAJR Am J Roentgenol
August 2019
1 Toronto Joint Department of Medical Imaging, University Health Network-Mount Sinai Hospital-Women's College Hospital, University of Toronto, 585 University Ave, 1PMB-283, Toronto, ON M5G 2N2, Canada.
The purpose of this study was to determine whether a novel morphologic characteristic of appendiceal mucoceles at CT-focal distal appendiceal dilatation with a segment of morphologically normal appendix proximally-could predict an underlying neoplastic pathologic abnormality before surgery and histopathologic assessment. A retrospective study was performed that assessed CT cases from 2012 through 2014. Cases showing morphologic features of a mucocele were identified and categorized into two subgroups: focal distal dilatation with a segment of normal appendix proximally and generalized appendiceal dilatation.
View Article and Find Full Text PDFIntensive Care Med
June 2019
Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.
Radiology
April 2019
From the Divisions of Cardiothoracic Imaging (J.C.L.R., K.H., J.K., T.B.C., M.P., E.T.N.), Thoracic Surgery (A.F.P., T.K.W., S.K., M.C., K.Y.), and Thoracic Pathology (M.C.), Toronto General Hospital, University Health Network, 585 University Ave, Toronto, ON, Canada M5G 2N2; Postgraduate Medical Education, Department of Medical Imaging, University of Toronto, Toronto, Canada (J.C.L.R.); and Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Combe Park, Bath, England, United Kingdom, BA1 3NG (J.C.L.R.).
Background CT-guided microcoil localization has been shown to reduce the need for thoracotomy or video-assisted thoracoscopic surgery (VATS) anatomic resection. However, only short-term follow-up after CT-guided microcoil localization and lung resection has been previously reported. Purpose To assess the diagnostic utility and recurrence-free survival over a minimum of 2 years following CT-guided microcoil localization and VATS.
View Article and Find Full Text PDFCurr Diab Rep
January 2019
Department of Medicine, Division of Nephrology, University Health Network, University of Toronto, Toronto, Canada.
Purpose Of Review: Type 2 diabetes (T2D) is associated with an increased risk of diabetic kidney disease (DKD), cardiovascular disease, and heart failure, in part through activation of the renin-angiotensin-aldosterone system (RAAS). Although recent cardiovascular outcome trials have identified newer therapeutic agents such as sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1)-receptor agonists that reduce the risk of these complications, patients still exhibit residual cardiorenal morbidity and mortality. Accordingly, the identification of pharmacological agents that attenuate micro- and macrovascular complications related to T2D is a major priority.
View Article and Find Full Text PDFCardiovasc Intervent Radiol
April 2019
Division of Vascular and Interventional Radiology, Department of Medical Imaging, Toronto General Hospital, University Health Network, University of Toronto, 585 University Ave, Toronto, ON, M5G 2N2, Canada.
The original version of this article published previously contained an error.
View Article and Find Full Text PDFCardiovasc Intervent Radiol
April 2019
Division of Vascular and Interventional Radiology, Department of Medical Imaging, Toronto General Hospital, University Health Network, University of Toronto, 585 University Ave, Toronto, ON, M5G 2N2, Canada.
Purpose: Minimally invasive alternatives to transurethral resection of the prostate (TURP) such as prostate arterial embolization (PAE) and photoselective vaporization of the prostate (PVP) are being explored as adjuncts in the care of patients with benign prostatic hyperplasia. However, there are conflicting reports of the costs of these procedures. The purpose of this study was to compare the direct and indirect hospital costs of TURP, PAE and PVP.
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
April 2019
Department of Orthopaedics and Trauma Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Purpose: To evaluate the usefulness of a novel MRI sequence strategy in the assessment of the periprosthetic anatomical structures after primary total knee arthroplasty.
Methods: Two MR sequences were retrospectively compared for the imaging of 15 patients with implanted cruciate-retaining/fixed-bearing TKAs (DePuy, PFC Sigma): a slice encoding sequence for metal artifact correction (SEMAC) and a standard sequence. Images were acquired on a 1.
AJR Am J Roentgenol
November 2018
1 Department of Medical Imaging, Toronto General Hospital, University of Toronto, 585 University Ave, Toronto, ON M5G 2N2, Canada.
Objective: The purpose of this study was to establish sex-specific chest CT measurement thresholds for detection of cardiac chamber enlargement with cardiac MRI as the reference standard.
Materials And Methods: Consecutive patients who underwent contrast-enhanced chest CT (64- or 320-MDCT) and cardiac MRI within a 7-day interval between August 2006 and August 2016 were included in this retrospective study (n = 217; 115 men, 102 women; mean age, 52.8 ± 15.
Radiographics
December 2018
From the Department of Medical Imaging, University of Toronto, University Health Network, Toronto General Hospital, 585 University Ave, Toronto, ON, Canada M5G 2N2.
Contrast material-enhanced US is recognized increasingly as a useful tool in a wide variety of hepatic and nonhepatic applications. The modality recently was approved for limited use for liver indications in adult and pediatric patients in the United States. Contrast-enhanced US uses microbubbles of gas injected intravenously as a contrast agent to demonstrate blood flow and tissue perfusion.
View Article and Find Full Text PDFAbdom Radiol (NY)
January 2019
Joint Department of Medical Imaging, Mount Sinai Hospital, University of Toronto, 600 University Ave., Toronto, ON, M5G 1X5, Canada.
Objective: To correlate the findings on 3T multiparametric prostate MRI using PIRADS version 2 with prostate biopsy results as the standard of reference.
Materials And Methods: 134 consecutive treatment naive patients (mean age 64 years, range 41-82 years) underwent MRI-directed prostate biopsy. MRI-TRUS fusion biopsy was used for 77 (77/134 = 57.
Respir Res
May 2018
Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, ON, Canada.
Background: Bronchoalveolar lavage (BAL) has proven to be very useful to monitor the lung allograft after transplantation. In addition to allowing detection of infections, multiple BAL analytes have been proposed as potential biomarkers of lung allograft rejection or dysfunction. However, BAL collection is not well standardized and differences in BAL collection represent an important source of variation.
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