Hyperuricemia - consequences of not initiating therapy. Benefits and drawbacks of treatment.

Hyperuricemia, characterized by elevated levels of uric acid in the body, is associated with several health risks, including gout, urolithiasis and cardiovascular disease. Although treatment options are available, they can lead to hypersensitivity reactions, particularly with allopurinol therapy. This paper provides a comprehensive review of the consequences of hyperuricemia, the need for treatment and the potential adverse effects of allopurinol, illustrated by a case study.

Magnesium bioresorbable scaffold (Magmaris) versus polymer biodegradable ultrathin drug-eluting stent (Ultimaster) in acute coronary syndrome. Mid-term outcomes (2 years).

Introduction: Acute coronary syndrome (ACS) is a well-known risk factor for adverse clinical outcomes in percutaneous coronary intervention (PCI). Therefore, evaluation of coronary stents in this challenging clinical scenario can provide unique information on device safety and efficacy. Bioresorbable scaffolds (BRS) were designed to overcome long-term complications related to permanent vessel caging with a permanent metallic drug-eluting stent (DES).

Assessment of aortic stiffness in computed tomography - methodology of radiological examination from 2000 to 2020.

Introduction: Vascular elasticity may be a predictive factor of various diseases. Although stiffening is thought to be a natural consequence of ageing, it can be accelerated by a number of pathological conditions such as hypertension, diabetes, or renal diseases. Aim of the study was to discuss the methodology used to assess aortic stiffness, with particular emphasis on radiological examination.

Ultrasound-Guided Infraclavicular Axillary Vein Versus Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients: A Randomized Trial.

Objectives: This clinical trial aimed to compare the ultrasound-guided in-plane infraclavicular cannulation of the axillary vein (AXV) and the ultrasound-guided out-of-plane cannulation of the internal jugular vein (IJV).

Design: A prospective, single-blinded, open label, parallel-group, randomized trial.

Setting: Two university-affiliated ICUs in Poland (Opole and Lublin).

Long-term outcomes following drug-eluting balloon or thin-strut drug-eluting stents for treatment of in-stent restenosis stratified by duration of dual antiplatelet therapy (DEB-Dragon Registry).

Introduction: Data regarding the duration of dual antiplatelet therapy (DAPT) in patients with drug-eluting stent restenosis (DES-ISR) treated with percutaneous coronary intervention (PCI) and drug-eluting balloons (DEB) or DES are not unambiguous.

Aim: To evaluate the relationship between long-term outcomes and the length of DAPT in patients treated with PCI due to DES-ISR with DEB or DES.

Material And Methods: Overall, a total of 1,367 consecutive patients with DES-ISR, who underwent PCI with DEB or DES between 2008 and 2019 entered the study.

The use of propranolol in adult burn patients: Safety and outcome influence.

Objectives: This study investigated safety and effect of propranolol on adult patients with severe burn.

Methods: A prospective study was conducted on 124 severely adult burn patients who were randomly divided into propranolol and non-propranolol group. Propranolol was given by nasogastric tube to achieve the target of lowering 15-20% of initial heart rate.

Current trends and procedural outcomes in the era of rotational atherectomy expansion in Poland in the period 2014-2017 (based on the nationwide ORPKI registry).

Introduction: The availability of rotational atherectomy (RA) has recently increased in Poland, which was followed by an increase in the rate of RA procedures and catheterization laboratories performing RA.

Aim: To assess current trends regarding the rapid increase in the number of RA procedures and catheterization laboratories performing RA.

Material An Methods: We analyzed patients treated with percutaneous coronary intervention (PCI) in the years 2014-2017 available in the nationwide ORPKI dataset.

W-type suture in Anderson-Hynes laparoscopic pyeloplasty: a novel approach to an old technique.

Introduction: Anderson-Hynes (A-H) dismembered pyeloplasty has remained nearly unchanged since its introduction in 1949. The authors present a modification of the uretero-pelvic anastomosis as described by Anderson and Hynes. The new approach, called the W-type suture, is thought to be more watertight and associated with fewer complications than the original.

Two cases of the bronchial carcinoid tumors successfully treated with the parenchymal-sparing bronchoplastic resections.

Carcinoid tumors account for 2% of primary lung tumors. We report two cases of the relatively young patients with typical and atypical carcinoid (AC) tumors that were managed successfully with a parenchymal-sparing bronchoplastic procedure.

Impact of pre-hospital electrocardiogram teletransmission on time delays in ST segment elevation myocardial infarction patients: a single-centre experience.

Introduction: Delay in diagnosis and treatment has a great influence on morbidity and mortality of ST-segment elevation myocardial infarction (STEMI) patients. Every 30 min of delay in reperfusion is associated with an 8% increase in mortality. ECG teletransmission was proved to effectively shorten time delays in STEMI treatment.

Patients with heart failure and concomitant chronic obstructive pulmonary disease participating in the Heart Failure Pilot Survey (ESC-HF Pilot) - Polish population.

Introduction: There is an increasing interest in comorbidities in heart failure patients. Data about chronic obstructive pulmonary disease (COPD) in the Polish population of heart failure (HF) patients are scarce. The aim of this study was to investigate the clinical characteristics, treatment differences and outcome according to COPD occurrence in the Polish population of patients participating in the ESC-HF Pilot Survey Registry.

Giant keratocystic odontogenic tumor of the mandible - a case report.

Background: The keratocystic odontogenic tumor (KCOT) is a relatively rare, benign neoplasm which develops in the maxilla or mandible, arising from the dental lamina or basal cells of the oral epithelium. It is often found incidentally and brings about late symptoms as it does not cause bone distension for a long time.

Case Report: The presented case is of a young woman with a giant keratocystic odontogenic tumor of the mandible.

Safety and efficacy assessment of carotid artery stenting in a high-risk population in a single-centre registry.

Introduction: Ischaemic stroke is the primary cause of long-term disability and the third most common cause of death. Internal carotid artery stenosis is an important risk factor for stroke and transient ischaemic attack (TIA). European Society of Cardiology (ESC) and American Heart Association (AHA) guidelines allow carotid artery stenting (CAS) as an alternative to endarterectomy in centres with low rates of death or stroke.

A 128-slice CT scanner helpful in localising coronary sinus ostium during CRT-D implantation - case report.

Background: Cardiac resynchronization therapy (CRT) has become a successful treatment option for symptomatic heart failure in patients with poor left ventricular (LV) systolic function and broad QRS complex in the surface electrocardiogram (ECG).

Case Report: In this report we present a case of a 70-year-old woman with advanced heart failure due to ischaemic heart disease who underwent an upgrade from VVIR stimulator (pacemaker, PM) to cardiac resynchronization therapy defibrillator (CRT-D). The first attempt was unsuccessful due to problems with inefficient cannulation of the orifice of the coronary sinus (CS).

Consequences of peripheral chemoreflex inhibition with low-dose dopamine in humans.

Low-dose dopamine inhibits peripheral chemoreceptors and attenuates the hypoxic ventilatory response (HVR) in humans. However, it is unknown: (1) whether it also modulates the haemodynamic reactions to acute hypoxia, (2) whether it also modulates cardiac baroreflex sensitivity (BRS) and (3) if there is any effect of dopamine withdrawal. We performed a double-blind, placebo-controlled study on 11 healthy male volunteers.

Giant congenital malformation of the perirectal plexus in computed tomography imaging - case report.

Background: Congenital arteriovenous malformation (AVM) in the pelvic area is uncommon in males.

Case Report: The described case is of a giant lesion of this type that caused recurrent hemorrhaging in the lower part of the gastrointestinal tract. Preliminary diagnosis of vascular pathology was made on the basis of an endoscopic examination that revealed numerous pulsating protuberances of the rectal wall, in which blood flow was identified by means of transrectal ultrasonography.

A case of a spontaneous splenorenal shunt associated with the nutcracker syndrome.

Background: Hypertension in the portal vein system stimulates the vascular system to develop a porto-caval collateral system, which occurs by adaptation of the already existing junctions between the porto-caval and the systemic circulation to changed conditions or by angiogenesis.

Case Report: We present a case of a 42-year-old man with alcoholic cirrhosis of the liver and exacerbation of chronic pancreatitis, whose computed tomography of the abdominal cavity revealed a massive varicoid dilatation of a vein of the spleen with a splenorenal shunt and tortuous dilated venous vessels in the retroperitoneal space and mesentery.

Conclusions: The unusual image of the mesenteric and retroperitoneal venous vessels in our patient resulted from the coexistence of collateral porto-systemic circulation and compression of the left renal vein.

Laparoscopic radical nephrectomy in extremely obese patients.

Laparoscopic radical nephrectomy has been widely accepted as the preferred management of low stage renal masses. Endoscopic management is advantageous for its reduction in perioperative and postoperative complications. In the mid-1990s, morbid obesity was considered a relative contraindication to laparoscopic technique.

Expression of HLA DR antigens, Fc IgG and C3 receptors on lung macrophages in sarcoidosis and idiopathic lung fibrosis.

The studies concerned an expression of HLA DR antigens, Fc IgG receptors and C3 complement on lung macrophages in patients with active sarcoidosis and idiopathic lung fibrosis as well as in the control group of smokers and nonsmokers. Macrophages were isolated by broncho-alveolar lavage with the aid of bronchofiberoscope. The expression of HLA DR antigens, Fc IgG and C3 receptors was tested before during and after the treatment.