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Article Synopsis
  • The study investigates the relationship between fatty acids in erythrocyte membranes and colorectal adenoma risk, addressing inconsistencies in previous research that relied on self-reported dietary data.
  • There were 904 adenoma cases and 835 polyp-free controls analyzed, with arachidonic acid levels linked to a significantly higher risk of colorectal adenomas (adjusted OR 1.66).
  • Conversely, higher levels of EPA showed a potential protective effect against advanced adenomas, suggesting that the type of PUFA may influence colorectal cancer risk.
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