4 results match your criteria: "36596Changhua Christian Hospital[Affiliation]"
The Effectiveness of Population Mass Screening to Oral Cancer: A Simulation Study.
Technol Cancer Res Treat
December 2022
School of Oral Hygiene, College of Oral Medicine, 534785Taipei Medical University, Taipei, Taiwan.
Article Synopsis
- Mass screening of high-risk populations, particularly those with smoking or betel quid chewing habits, has successfully reduced oral cancer mortality, yet the specific effectiveness of different screening methods is not well understood.
- A simulation was created for a hypothetical cohort of 8 million individuals aged 30 and older to analyze the impact of various screening strategies, validating results against real-world data from Taiwan and India.
- The study found a 40% reduction in advanced oral cancer risk and a 29% decrease in mortality after six years with a biennial screening approach; improvements in attendance and referral rates also contributed significantly to outcomes, highlighting the importance of compliance in screening effectiveness.
Tumor Volume Reduction Rate to Induction Chemotherapy is a Prognostic Factor for Locally Advanced Head and Neck Squamous Cell Carcinoma: A Retrospective Cohort Study.
Technol Cancer Res Treat
July 2022
Department of Radiation Oncology, 38020China Medical University Hospital, Taichung.
Aim of this retrospective cohort study is to evaluate the prognostic value of tumor volume reduction rate status post-induction chemotherapy in locally advanced head and neck squamous cell carcinoma. Patients newly diagnosed from year 2007 to 2016 at a single center were included in this retrospective study. All patients had received induction Taxotere, Platinum, Fluorouracil followed by daily definitive intensity-modulated radiotherapy for 70 Gy in 35 fractions concurrent with or without cisplatin-based chemotherapy.
View Article and Find Full Text PDFProfiling of Protein Adducts of Estrogen Quinones in 5-Year Survivors of Breast Cancer Without Recurrence.
Cancer Control
March 2022
Department of Environmental Engineering, 34916National Chung Hsing University, Taichung, Taiwan.
Aims: The aim of this study was to simultaneously analyze estrogen quinone-derived adducts, including 17β-estradiol-2,3-quinone (E-2,3-Q) and 17β-estradiol-3,4-quinone (E-3,4-Q), in human albumin (Alb) and hemoglobin (Hb) derived from breast cancer patients with five-year postoperative treatment without recurrence in Taiwan and to evaluate the treatment-related effects on the production of these adducts.
Settings And Design: Cohort Blood samples derived from breast cancer 5-year survivors without recurrence were collected. Albumin and hemoglobin adducts of E-3,4-Q and E-2,3-Q were analyzed to evaluate the degree of disposition of estrogen to quinones and to compare these adduct levels with those in patients before treatment.
Prediction of Institutionalization for Patients With Dementia in Taiwan According to Condition at Entry to Dementia Collaborative Care.
J Appl Gerontol
May 2022
Department of Psychiatry, 36596Changhua Christian Hospital, Changhua, Taiwan.
This study aimed to examine the institutionalization rate in patients with dementia in Taiwan, identify the predictors of institutionalization, and conduct a mediation analysis of caregiver burden between neuropsychiatric symptoms and institutionalization. We analyzed data from a retrospective cohort registered in dementia collaborative care ( = 518). The analyses applied univariate and multivariate Cox proportional hazard regression with Firth's penalized likelihood to assess the relationship between each predictor at entry and institutionalization for survival analysis.
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