Chitosan-platelet-rich plasma implants improve rotator cuff repair in a large animal model: Pilot study.

Freeze-dried formulations of chitosan can be solubilized in platelet-rich plasma (PRP) to form injectable implants that are used as an adjunct treatment during surgical repair of the rotator cuff. The purpose of the current study was to assess chitosan-PRP implant residency, test safety, and assess efficacy over standard-of-care controls in a sheep model of rotator cuff repair. The infraspinatus tendon was transected unilaterally and immediately repaired with suture anchors in 22 skeletally mature ewes.

Understanding Discussions of Sexual Assault in Young Women on a Peer Support Mental Health App: A Content Analysis.

Trauma narratives may have been influenced by the Me Too movement, with thousands of individuals disclosing sexual violence stories online. Youth, the largest demographic of online users, may prefer the anonymity of the Internet to discuss experiences of sexual assault. Understanding the ways that young women, especially those experiencing mental health difficulties, discuss their experiences is important as they are at higher risk of revictimization and continued poor mental health.

Promoting Healthy Food Access and Nutrition in Primary Care: A Systematic Scoping Review of Food Prescription Programs.

Objective: To conduct a scoping review to synthesize evidence on food prescription programs.

Data Source: A systematic search of PubMed, CINAHL, Web of Science, Embase, and the Cochrane Library was conducted using key words related to setting, interventions, and outcomes.

Study Inclusion And Exclusion Criteria: Publications were eligible if they reported food prescription administered by a health care practitioner (HCP) with the explicit aim of improving healthy food access and consumption, food security (FS), or health.

"The Rest of my Childhood was Lost": Canadian Children and Adolescents' Experiences Navigating Inflammatory Bowel Disease.

Children and adolescents with Inflammatory Bowel Disease (IBD) face significant and unique challenges related to their condition. The aim of this study was to better understand some of these challenges, and to explore how Canadian youth respond to them. We interviewed 25 pediatric patients with IBD, ranging in age from 10-17, to find out about their illness experiences.

Is Psychopathy a Mental Disorder or an Adaptation? Evidence From a Meta-Analysis of the Association Between Psychopathy and Handedness.

Psychopathy has historically been conceptualized as a mental disorder, but there is growing evidence that it may instead be an alternative, adaptive life history strategy designed by natural selection. Although the etiology of mental disorders is not fully understood, one likely contributor is perturbations affecting neurodevelopment. Nonright-handedness is a sign of such perturbations, and therefore can be used to test these competing models.

International Guidelines for Veterinary Tumor Pathology: A Call to Action.

Standardization of tumor assessment lays the foundation for validation of grading systems, permits reproducibility of oncologic studies among investigators, and increases confidence in the significance of study results. Currently, there is minimal methodological standardization for assessing tumors in veterinary medicine, with few attempts to validate published protocols and grading schemes. The current article attempts to address these shortcomings by providing standard guidelines for tumor assessment parameters and protocols for evaluating specific tumor types.

The Ontario Forensic Mental Health System: A Population-based Review.

Objective: The purpose of this study was to increase the understanding of the Canadian forensic psychiatry system by providing a population-based overview of the Ontario forensic mental health system.

Methods: Data were collected on 1,240 accused adults who were subject to the jurisdiction of the Ontario Review Board (ORB) between 2014 and 2015. Archival data were retrieved from annual ORB hearing hospital reports for accused supervised by all nine adult forensic psychiatry facilities across Ontario.

Problem Orientation and Psychological Distress Among Adolescents: Do Cognitive Emotion Regulation Strategies Mediate Their Relationship?

Adolescence is a critical period for the development of attitudes and skills crucial in determining vulnerability for psychological distress. The current study aimed to focus on the association of problem orientation and cognitive emotion regulation strategies with psychological distress and demonstrate the mediator roles of adaptive and maladaptive cognitive emotion regulation strategies in the association of problem orientation with psychological distress. Data were collected from 335 adolescents (167 female) aged 14-to-18 years (M= 14.

Bullshit Ability as an Honest Signal of Intelligence.

Navigating social systems efficiently is critical to our species. Humans appear endowed with a cognitive system that has formed to meet the unique challenges that emerge for highly social species. Bullshitting, communication characterised by an intent to be convincing or impressive without concern for truth, is ubiquitous within human societies.

Correlation Between KIT Expression and Mutations in 2 Subtypes of Canine Oral Melanocytic Neoplasms.

mutations have been reported in 15% to 40% of certain human melanoma subtypes, including those histologically similar to canine oral malignant melanomas. Therapeutic response to tyrosine kinase inhibitors has been demonstrated in those human patients. As canine oral malignant melanomas tend to have a poor prognosis despite aggressive surgical removal, evaluation of KIT expression and identification of mutations in canine oral melanocytic neoplasms was performed to determine if there is any indication that tyrosine kinase inhibitor drugs might effectively treat any of these cases.

Lymphoma in Psittacine Birds: A Histological and Immunohistochemical Assessment.

In psittacine birds, round cell neoplasms that originate from lymphocytes, plasma cells, histiocytes, or mast cells are sporadic and poorly described. The lack of morphological and immunohistochemical diagnostic criteria or grading schemes make specific diagnoses and prognoses challenging. We assessed cases of psittacine birds diagnosed with round cell neoplasia from 3 North American veterinary diagnostic laboratories to describe the diagnostic features of these tumors.

Frequency of fruit juice consumption and association with nutrient intakes among Canadians.

Background: In Canada, studies on consumption of 100% fruit juice and nutrient intakes are limited.

Aim: This study aimed to evaluate nutrient intakes and adequacy of intake by frequency of fruit juice consumption.

Methods: Individuals ≥1 year ( = 34,351) participating in the Canadian Community Health Survey, 2004 with a 24-hour dietary recall and reported usual frequency of fruit juice consumption (assumed to be 100% juice) were categorized by frequency of consumption as <0.