Molecular Phosphide Complexes of Zirconium.

Molecular Zr phosphides are extremely rare, with no examples containing a one-coordinated and terminal triple-bonded phosphorus atom. We report here an isolable and relatively stable Zr phosphide complex, [(PN)Zr≡P{μ-Na(OEt)}] (), stemming from a cyclometalated Zr-hydride, [(PN)(PN')Zr(H)] (), and NaPH. Complex is prepared from two- or one-electron reductions of precursors [(PN)ZrCl] () or metastable Zr[(PN)ZrCl], respectively.

Fungal Planet description sheets: 1697-1780.

Novel species of fungi described in this study include those from various countries as follows: , from accumulated snow sediment sample. , on leaf spots of . , on submerged decaying wood in sea water, on , as endophyte from healthy leaves of .

Transformer-based neural speech decoding from surface and depth electrode signals.

This study investigates speech decoding from neural signals captured by intracranial electrodes. Most prior works can only work with electrodes on a 2D grid (i.e.

Likelihood of Preterm Birth in Patients After Antenatal Corticosteroid Administration in Relation to Diagnosis and Confounding Risk Factors: A Retrospective Cohort Study.

: In the case of threatened preterm birth (PTB) before the 34th week of pregnancy, the application of antenatal corticosteroids (ACSs) for the maturation of the fetal lung is a standard procedure in perinatal medicine. Common diagnoses for ACS use in pregnancy are the preterm rupture of membranes (PPROMs), placental bleeding, premature labor, preeclampsia, oligohydramnios, amniotic infection syndrome (AIS), and cervical insufficiency. The aim of this study was to investigate whether the current diagnosis, which results in ACS, and the patient's risk factors influence the risk of PTB events.

The genus in Benin, with the description of , sp. nov.

Intensive mycological surveys in southern Benin focused on species of (Pleosporales) resulted in the collection and sequencing of numerous specimens on dead plant debris of different hosts. Majority of the collections belonged to the monomorphic species , except for two specimens of a hitherto unknown species, which is introduced as . The fungus was collected on dead twig of still attached to the tree and dead peduncle of .

Burden of coronary artery calcification in ANCA-associated vasculitis.

Background: Cardiovascular disease (CVD) is a leading cause of death in ANCA-associated vasculitis (AAV). Screening and primary cardiovascular prevention may improve outcomes.

Methods: We identified patients in the 2002-2019 Mass General Brigham AAV cohort with thoracic CT scans obtained for other clinical purposes.

Successful pregnancy of an SMA type 3 sitter on Nusinersen therapy - a case report.

Background: Due to improved treatment options, more SMA patients reach childbearing age. Currently, limited data on pregnant SMA patients is available, especially in relation to disease-modifying therapies (DMT). This case report helps to elucidate new approaches for future guidelines in the management of pregnancy and SMA.

Mechanistic Investigation of the Ce(III) Chloride Photoredox Catalysis System: Understanding the Role of Alcohols as Additives.

Photocatalytic C-H activation is an emerging area of research. While cerium chloride photocatalysts have been extensively studied, the role of alcohol additives in these systems remains a subject of ongoing discussion. It was demonstrated that the photocatalyst [NEt][CeCl] () produces •Cl and added alcohols exhibit zero-order kinetics.

Characterization of gallbladder disease in metachromatic leukodystrophy across the lifespan.

Metachromatic leukodystrophy (MLD) is a progressive demyelinating disorder resulting from the toxic accumulation of sulfatides. The stereotyped neurodegeneration of MLD is well understood, and cases are categorized into subtypes by age at neurologic onset: late infantile (LI), juvenile (J), and adult. The systemic burden of disease, such as gallbladder involvement, however, is less well characterized.

Shock index reference ranges in the first 48 h postpartum following elective cesarean delivery: A prospective cohort study.

Purpose: To determine the reference values for the shock index (SI) in postpartum patients undergoing elective cesarean delivery with regional anesthesia.

Methods: This prospective study was conducted at our tertiary center between August 1, 2023, and March 1, 2024. We calculated the reference values for the SI within the first 48 h postpartum for patients who underwent elective cesarean delivery after the 34th week of gestation.

Expanding the phenotypic and genetic spectrum of GTPBP3 deficiency: findings from nine Chinese pedigrees.

Background: GTPBP3 catalyzes τm(s) U biosynthesis at the 34th wobble position of mitochondrial tRNAs, the hypomodification of τmU leads to mitochondrial disease. While twenty-three variants of GTPBP3 have been reported worldwide, the genetic landscape in China remains uncertain.

Methods: By using whole-exome sequencing, the candidate individuals carrying GTPBP3 variants were screened and identified.

Leptospirosis manifested with severe pulmonary hemorrhagic syndrome successfully treated with veno-venous extracorporeal membrane oxygenation: A case report and literature review.

Rationale: The mortality rate associated with pulmonary hemorrhage induced by leptospirosis is notably high. Available treatment modalities are limited, and their efficacy has not been fully demonstrated. Here, we present the case report of a patient with leptospirosis-induced pulmonary hemorrhagic syndrome.

The conserved wobble uridine tRNA thiolase Ctu1 is required for angiogenesis and embryonic development.

Cytosolic thiouridylase is a conserved cytoplasmic tRNA thiolase composed of two different subunits, CTU1 and CTU2. CTU2 serves as a scaffold protein, while CTU1 catalyzes the 2-thiolation at the 34th wobble uridine of the anticodon loop. tRNAGlnUUG, tRNAGluUUC, and tRNALysUUU are the tRNA substrates that are modified with a thiol group at the C2 positions (s2) by CTU1, and also with a methoxycarbonylmethyl group at the C5 positions (mcm5) by Elongator and ALKBH8.

Catheter ablation in rate-controlled atrial fibrillation with severely reduced ejection fraction: intervention for irregularity-mediated cardiomyopathy.

Background: Recent evidence suggests atrial fibrillation (AF) causes cardiomyopathy due to remodeling driven by both irregular rate and rhythm. Atrial fibrillation (AF) ablation in patients with reduced ejection fraction (EF) ≤ 35% has been shown to improve EF and mortality. It is unknown whether the benefits of AF ablation among patients with reduced EF are affected by the degree of pre-ablation rate control.

Non-oliguric acute renal failure secondary to a potentially lethal dose of caffeine with acute intoxication: a case report.

Background: Recently, the incidence of caffeine intoxication has been on an upward trend, with severe outcomes. However, acute kidney injury (AKI) resulting from renal pathologies secondary to caffeine intoxication is rare, and the pathophysiological mechanisms underlying AKI are unclear.

Case Presentation: A female patient in her 20s ingested an over-the-counter drug containing caffeine.

Optical Control of TRPM8 Channels with Photoswitchable Menthol.

Transient receptor potential melastatin 8 (TRPM8) channels are well known as sensors for cold temperatures and cooling agents such as menthol and icilin and these channels are tightly regulated by the membrane lipid phosphoinositol-4,5-bisphosphate (PIP). Since TRPM8 channels emerged as promising drug targets for treating pain, itching, obesity, cancer, dry eye disease, and inflammation, we aimed at developing a high-precision TRPM8 channel activator, to achieve spatiotemporal control of TRPM8 activity with light. In this study, we designed, synthesized and characterized the first photoswitchable TRPM8 activator azo-menthol (AzoM).

Two new cave-dwelling species of Bent-toed Geckos from Saraburi and Loei provinces, Thailand (Squamata: Gekkonidae: Cyrtodactylus).

We describe Cyrtodactylus meesookae sp. nov. from a cave on Khao Nam Phu (14°34'33.

Barbenigma Powell & Miller, a bizarre new genus and two new species of scale insects (Hemiptera: Coccomorpha: Ortheziidae) from the United States.

A strange new genus and two species of scale insect from the United States, Barbenigma Powell & Miller, gen. nov. and Barbenigma biza Powell & Miller, sp.

A new species of Pseudostilobezzia Wirth & Ratanaworabhan (Diptera: Ceratopogonidae) from Vietnam.

A new species of Pseudostilobezzia Wirth & Ratanaworabhan is described, the third in this small genus, from Vietnam and based on two females. A key is provided to distinguish the three species, all restricted to the Oriental Region, in Vietnam or the nearby Hainan province, China. The phylogenetic relationship between this genus and other Ceratopogonidae suggests that it may be a somewhat distinctive lineage within Stilobezzia Kieffer.

Three new species of Puto giant mealybugs (Hemiptera: Coccomorpha: Putoidae) from Mexico and Guatemala, with keys to New World adult females and World adult males.

Three new species of Puto Signoret, 1876 are described and illustrated from material intercepted at US plant quarantine inspection, including the adult females, all available immature stages, and for two species, the adult male. Puto philo Powell & Miller, sp. n.

The burden of diseases, injuries, and risk factors by state in the USA, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.

Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides a comprehensive assessment of health and risk factor trends at global, regional, national, and subnational levels. This study aims to examine the burden of diseases, injuries, and risk factors in the USA and highlight the disparities in health outcomes across different states.

Methods: GBD 2021 analysed trends in mortality, morbidity, and disability for 371 diseases and injuries and 88 risk factors in the USA between 1990 and 2021.