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551 results match your criteria: "3333 University Way[Affiliation]"
Nucleic Acids Res
December 2024
Bioinformatics Group, Wageningen University & Research, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readable way, the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard and repository was initiated in 2015.
View Article and Find Full Text PDFCan J Diabetes
November 2024
School of Health and Exercise Sciences; University of British Columbia, Okanagan Campus; 3333 University Way, Kelowna, BC, V1V 1V7, Canada. Electronic address:
Objective: Previous reviews have highlighted the efficacy of lifestyle diabetes prevention programs (DPPs) in decreasing type 2 diabetes (T2D) risk; however, the participating population is predominantly white. This is concerning as ethnically diverse populations are disproportionately affected by T2D. The objective of this scoping review was to 1) summarize existing tailored DPPs and 2) provide recommendations for future program implementation to improve access and reach for diverse populations.
View Article and Find Full Text PDFLandsc Ecol
November 2024
Département de Phytologie, Faculté des Sciences de L'Agriculture et de L'Alimentation, Université Laval, 2425 Rue de L'Agriculture, Québec, QC G1V 0A6 Canada.
Context: Intensive agriculture increases crop yields, but harms biodiversity and associated ecosystem services such as pollination. To sustain wild-bee pollination in intensive agricultural landscapes, a minimum of (semi-) natural habitat is needed in the vicinity of crop fields. However, restoration of (semi-) natural habitat is a challenge, especially when most land is allocated to commodity production.
View Article and Find Full Text PDFWater Res
January 2025
School of Engineering, The University of British Columbia Okanagan 3333 University Way, Kelowna, BC, V1V 1V7, Canada. Electronic address:
Water quality modelling in Water Distribution systems (WDS) is frequently affected by uncertainties in input variables such as base demand and decay constants. When utilizing simulation tools like EPANET, which necessitate exact numerical inputs, these uncertainties can result in inaccurate simulations. This study proposes a novel framework that leverages unsupervised machine learning, specifically a Gaussian Mixture Model (GMMs), to represent and integrate these uncertainties in the simulation.
View Article and Find Full Text PDFJ Gen Intern Med
October 2024
Centre for Health Education Scholarship, University of British Columbia, Vancouver, Canada.
Background: Indirect supervision is essential for granting autonomy to learners. Sometimes referred to as leaving the learner "unsupervised," there is growing recognition that learners and supervisors engage in clinical support through ongoing interactions, albeit at a distance.
Objective: To understand how the complementary activities of asking for and providing clinical support at a distance come together as indirect supervision by identifying the natural language used between learners and supervisors.
Trials
October 2024
Department of Psychology, University of Calgary, 2500 University Drive Northwest, Calgary, AB, T2N 1N4, Canada.
Genome
December 2024
Biology Department, Vancouver Island University, 900 Fifth Street, Nanaimo, BC V9R 5S5, Canada.
Mitochondrial DNA is commonly used in population genetic studies to investigate spatial structure, intraspecific variation, and phylogenetic relationships. The control region is the most rapidly evolving and largest non-coding region, but its analysis can be complicated by heteroplasmic signals of genome duplication in many mammals, including felids. Here, we describe the presence of heteroplasmy in the control region of Canada lynx () through intra-individual sequence variation.
View Article and Find Full Text PDFBeni Suef Univ J Basic Appl Sci
July 2024
Department of Biology, The University of British Columbia, Okanagan Campus, 3333 University Way, Kelowna, BC V1V 1V7 Canada.
Background: Several members of the Lamiaceae family of plants produce large amounts of essential oil [EO] that find extensive applications in the food, cosmetics, personal hygiene, and alternative medicine industries. There is interest in enhancing EO metabolism in these plants.
Main Body: Lavender produces a valuable EO that is highly enriched in monoterpenes, the C class of the isoprenoids or terpenoids.
Chemosphere
August 2024
School of Engineering, University of Northern British Columbia, 3333 University Way, Prince George, BC, V2N 4Z9, Canada. Electronic address:
Chemistry
July 2024
School of Engineering, Faculty of Applied Science, The University of British Columbia, 3333 University Way, Kelowna, BC V1V 1V7, Canada.
Hybrid supercapacitors (HSCs) bridge the unique advantages of batteries and capacitors and are considered promising energy storage devices for hybrid vehicles and other electronic gadgets. Lithium-ion capacitors (LICs) have attained particular interest due to their higher energy and power density than traditional supercapacitor devices. The limited voltage window and the deterioration of anode materials upsurged the demand for efficient and stable electrode materials.
View Article and Find Full Text PDFBiol Rev Camb Philos Soc
August 2024
Geomatics and Landscape Ecology Laboratory, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, K1S 5B6, Canada.
Anthropogenic habitat loss is widely recognized as a primary environmental concern. By contrast, debates on the effects of habitat fragmentation persist. To facilitate overcoming these debates, here we: (i) review the state of the literature on habitat fragmentation, finding widespread confusion and stigma; (ii) identify consequences of this for biodiversity conservation and ecosystem management; and (iii) suggest ways in which research can move forward to resolve these problems.
View Article and Find Full Text PDFPharmaceutics
December 2023
SKiN Centre for Dermatology, 775 Monaghan Rd, Peterborough, ON K9J 5K2, Canada.
Psoriasis is a common chronic immune-mediated disease with many comorbidities and impacts on quality of life. Among the treatments for psoriasis, phosphodiesterase-4 (PDE4) inhibitors are emerging with expanding options. PDE4 inhibitors play a pivotal role in the inflammatory cascade by degrading cyclic adenosine monophosphate (cAMP), contributing to pro-inflammatory mediator production.
View Article and Find Full Text PDFEnviron Manage
April 2024
Graduate Program in Environmental Management (PPGAMB), Universidade Positivo. Monitoring and Modeling Research Group, Rua Professor Pedro Viriato Parigot de Souza, 5300, Curitiba, PR, 81270-020, Brazil.
Environmental impact assessment (EIA) has become one of the most widespread environmental management instruments. Despite this, EIA is routinely criticized for being ineffective at impacting decision-making. This study compared the EIA systems of Paraná, Brazil and California, United States using the effectiveness dimensions from the EIA literature.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2024
School of Engineering, Environmental Engineering Program, University of Northern British Columbia (UNBC), 3333 University Way, Prince George, British Columbia, V2N 4Z9, Canada.
Industrial wastewater generated from various production processes is often associated with elevated pollutant concentrations and environmental hazards, necessitating efficient treatment. Floating wetlands (FWs) have emerged as a promising and eco-friendly solution for industrial wastewater treatment, with numerous successful field applications. This article comprehensively reviews the removal mechanisms and treatment performance in the use of FWs for the treatment of diverse industrial wastewaters.
View Article and Find Full Text PDFPEC Innov
December 2023
University of British Columbia, T201-2211 Wesbrook Mall, Vancouver, BC V6T 2B5, Canada.
Objective: To develop and evaluate an evidence-based online Reflective Guide to prepare Registered Nurses and Nurse Practitioners for important professional, personal, and relational roles in MAID in Canada.
Methods: The Reflective Guide was developed inductively from qualitative interviews with 120 Canadian nurses. The online Guide contains a 15 min documentary video and five areas of content: nurses' experiences, making moral sense of MAID, best practices, common dilemmas, and self-care strategies.
Sports Med Open
December 2023
School of Health and Exercise Sciences, University of British Columbia, 3333 University Way, Kelowna, BC, V1V1V7, Canada.
Background: Individuals with spinal cord injury (SCI) report high levels of neuropathic pain. Current treatment options are primarily pharmaceutical, despite their limited effectiveness. Exercise may reduce neuropathic pain among persons with SCI; however, the optimal dose of exercise required to elicit analgesic effects remains unknown.
View Article and Find Full Text PDFTrials
November 2023
University of British Columbia, 2329 West Mall, Vancouver, BC, V6T 1Z4, Canada.
Background: Limited mobility in older adults consistently predicts both morbidity and mortality. As individuals age, the rates of mobility disability increase from 1.0% in people aged 15-24 to 20.
View Article and Find Full Text PDFBMC Public Health
November 2023
University of Northern British Columbia, Prince George, Canada.
Background: Physical activity occurs across various domains including leisure/recreation, for transportation, or for work or household reasons. Rural and urban active living environments are characterized by different opportunities for physical activity within each domain which may translate into different patterns of behavior. The aim of this study was to compare rural-urban differences in physical activity across different domains, and explore interactions between sociodemographic factors, physical activity domains, and rurality.
View Article and Find Full Text PDFBMC Pulm Med
October 2023
School of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Background: The prevalence of COPD continues to rise. To address the challenges to provide high quality COPD care in rural and northern communities, leaders in one rural and northern community in Western Canada sought to change the culture of COPD screening and care. Recognizing effective assessment, diagnosis, and treatment for patients with COPD are crucial to improve outcomes, a program was developed between 2012 and 2021 to enhance primary care for COPD patients.
View Article and Find Full Text PDFBMC Health Serv Res
October 2023
Department of Psychology, University of British Columbia, 3333 University Way, Kelowna, BC, V1V 1V7, Canada.
Background: Chronic pain is a highly prevalent and disabling condition which is often undertreated and poorly managed in the community. The emergence of COVID-19 has further complicated pain care, with an increased prevalence of chronic pain and mental health comorbidities, and burnout among physicians. While the pandemic has led to a dramatic increase in virtual health care visits, the uptake of a broader range of eHealth technologies remains unclear.
View Article and Find Full Text PDFJ Soils Sediments
June 2023
Ministry of Forests Omineca Region, Research and Forest Health, 5th Flr. 499 George St., Prince George, BC V2L 1R5 Canada.
Purpose: This study (1) investigated the extent to which flocculation and the hydrological and morphological attributes of an interior salmon-bearing river regulate the seasonal storage of marine-derived nutrients (MDN) and (2) compared the contribution of MDN to the fine bed sediment relative to other nutrient sources to the river.
Methods: Previous research has determined that the co-existence of re-suspended fine sediment, generated by salmon redd construction, with salmonid excretion and decay products in the water column creates ideal conditions for the flocculation of these inorganic and organic particles. Stored and suspended fine bed sediment was sampled from seven sites with varying morphologies and bed substrate down the length of a large spawning river in the interior of British Columbia over a 12-month period.
Res Involv Engagem
September 2023
University of Waterloo, 200 University Ave. W., Waterloo, ON, N2L3G1, Canada.
Promoting wellbeing of persons with dementia and their families is a priority of research and practice. Engaging diverse partners, including persons with dementia and their families, to co-develop interventions promotes relevant and impactful solutions. We describe the process, output, and lessons learned from the dementia resources for eating, activity, and meaningful inclusion (DREAM) project, which co-developed tools/resources with persons with dementia, care partners, community service providers, health care professionals, and researchers with the aim of increasing supports for physical activity, healthy eating, and wellbeing of persons with dementia.
View Article and Find Full Text PDFTher Adv Urol
September 2023
School of Nursing, University of Northern British Columbia, Prince George, BC, Canada.
Sci Total Environ
December 2023
Trent School of the Environment, Trent University, 1600 West Bank Dr., Peterborough, ON K9J 7B8, Canada.
Increasing forest cover by regreening mining and smelting degraded landscapes provides an opportunity for global carbon (C) sequestration, however, the reported effects of regreening on soil C processes are mixed. One of the world's largest regreening programs is in the City of Greater Sudbury, Canada and has been ongoing since 1978. Prior to regreening, soils in the City of Greater Sudbury area were highly eroded, acidic, rich in metals, and poor in nutrients.
View Article and Find Full Text PDFSci Rep
August 2023
Gut Microbes and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich, NR4 7UQ, UK.
Alterations in intestinal mucin glycosylation have been associated with increased intestinal permeability and sensitivity to inflammation and infection. Here, we used mice lacking core 3-derived O-glycans (C3GnT) to investigate the effect of impaired mucin glycosylation in the gut-brain axis. C3GnT mice showed altered microbial metabolites in the caecum associated with brain function such as dimethylglycine and N-acetyl-L-tyrosine profiles as compared to C3GnT littermates.
View Article and Find Full Text PDF