[Effects of fibroblast growth factor-10 on the secretions of transforming growth factor-alpha, platelet-derived growth factor-AB and vascular endothelial growth factor by normal adult human keratinocytes in culture].

Objective: To evaluate the effect of fibroblast growth factor-10 (FGF-10) on the secretion of transforming growth factor-alpha (TGF-alpha), platelet-derived growth factor-AB (PDGF-AB) and vascular endothelial growth factor (VEGF) by human keratinocytes.

Methods: Concentrations of FGF-10 used were 4, 16, 125 and 500 ng/ml. Serum-free keratinocyte growth medium without EGF or with EGF were as negative control and positive control, respectively.

[Expression of mRNA and protein of ubiquitin in diaphragmatic muscle in burned rats with sepsis in early stage].

Objective: To study the expressions of mRNA and protein of ubiquitin in diaphragmatic muscle in burned rats with sepsis.

Methods: The model of burn sepsis was replicated by subjecting the rats to 30 percent total body surface area (TBSA) III degree burn followed immediately by administration of endotoxin (6 mg/kg) into the peritoneal cavity. The rats were randomly divided into 2-and 6-hour groups and a normal control group, with 9 rats in each group.

[The significance of the expressions of lipopolysaccharide binding protein mRNA and lipopolysaccharide receptor CD14 mRNA in the liver of burned rat].

Objective: To explore the significance and the correlation between enteric endotoxin translocation and hepatic endotoxin -- sensitivity -- enhancing system--lipopolysaccharide -- binding protein (LBP)/lipopolysaccharide receptor CD14 (LBP/CD14) after burn.

Methods: Wistar rats subjected to 35% III degree burn were employed as the model. The rats were randomly divided into three groups: i.