1 results match your criteria: "304 Clinical Department of General Hospital of PLA[Affiliation]"
Antisense oligodeoxynucleotide targeting HER2 mRNA sensitized docetaxel in breast cancer treatment.
Pharm Biol
November 2011
304 Clinical Department of General Hospital of PLA, Beijing, PR China.
Context: Human epidermal growth factor receptor 2 (HER2) is one of the oncogenes closely associated with the development and prognosis of breast carcinoma. Down-regulation of HER2 mRNA by antisense oligodeoxynucleotide (ASO) HER2 has been suggested to be a feasible treatment for patients with breast carcinoma.
Objective: The antitumor effects of ASO HA6722 were investigated in vitro and in vivo.