2 results match your criteria: "301 University Building[Affiliation]"

The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration.

Aging Cell

October 2015

Departments of Neurology, Neuroscience and Cell Biology, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, 301 University Building, Medical Research Building, Galveston, TX, 77555-1045, USA.

Various neurodegenerative diseases are characterized by the accumulation of amyloidogenic proteins such as tau, α-synuclein, and amyloid-β. Prior to the formation of these stable aggregates, intermediate species of the respective proteins-oligomers-appear. Recently acquired data have shown that oligomers may be the most toxic and pathologically significant to neurodegenerative diseases such as Alzheimer's and Parkinson's.

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Sex hormone effects in non-pregnant rat and human myometrium.

Eur J Obstet Gynecol Reprod Biol

May 2003

Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Texas Medical Branch, 301 University Building, Galveston, TX 77555-1062, USA.

Objective: To study effects of sex hormones on spontaneous contractility and on the effects of depolarizing agent potassium chloride (KCl), M-cholinoceptor and prostaglandin receptor agonists on non-pregnant rat and human uterine tissues.

Study Design: Uterine rings from ovariectomized rats treated with sex hormones or placebo, and uterine strips from premenopausal and postmenopausal women were equilibrated in Krebs buffer (t=37 degrees C, pH approximately 7.4) for isometric tension recordings.

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