1 results match your criteria: "30026 Vellore Institute of Technology[Affiliation]"
Molecular docking and evaluation of glucosamine sulfate targeting MMP-3, MMP-9, and IL-4 for potential osteoarthritis treatment.
Drug Metab Pers Ther
December 2024
School of Mechanical Engineering, 30026 Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Objectives: This study intended to investigate the potential of glucosamine sulfate (GS) as an inhibitor of genes involved in osteoarthritis (OA) development. Despite GS is often used for OA treatment due to its cartilage preservation and minimum side effects, the molecular mechanism behind its interactions remains unknown.
Methods: Molecular docking was conducted to analyze the interactions between glucosamine sulfate and genes associated with OA such as matrix metalloproteinase-3 (MMP-3), MMP-9, and interleukin-4 (IL-4).