6 results match your criteria: "3 University of Manchester[Affiliation]"
Proton-driven plasma wakefield acceleration in AWAKE.
Philos Trans A Math Phys Eng Sci
August 2019
3 University of Manchester, Manchester , UK.
In this article, we briefly summarize the experiments performed during the first run of the Advanced Wakefield Experiment, AWAKE, at CERN (European Organization for Nuclear Research). The final goal of AWAKE Run 1 (2013-2018) was to demonstrate that 10-20 MeV electrons can be accelerated to GeV energies in a plasma wakefield driven by a highly relativistic self-modulated proton bunch. We describe the experiment, outline the measurement concept and present first results.
View Article and Find Full Text PDFDynamic Optical Coherence Tomography Is a New Technique for Imaging Skin Around Lower Extremity Wounds.
Int J Low Extrem Wounds
March 2019
2 General Hospital Augsburg, Augsburg, Germany.
Chronic wounds such as venous leg ulcers invariably heal slowly and recur. In the case of venous leg ulcers, poor healing of chronic wounds is variously attributed to ambulatory hypertension, impaired perfusion and diffusion, presence of chronic inflammation at wound sites, lipodermatosclerosis, and senescence. The aim of this study was to investigate whether a new technique, optical coherence tomography (OCT), which permits imaging of blood capillaries in the peri-wound skin, can provide new insights into the pathology.
View Article and Find Full Text PDFNeeds in Service Provision for Oral Health Care in Older People: A Comparison Between Greater Manchester (United Kingdom) and Utrecht (the Netherlands).
Int J Health Serv
October 2018
4 North Wales Organisation for Randomised Trials in Health (Clinical Trials Unit), Bango University, Gwynedd, UK.
Retaining natural teeth for longer, together with increasing care dependency in the elderly, has the potential to hamper adequate oral self-care and service provision. The aim of this qualitative study was to compare and contrast views from a multi-stakeholder perspective on the future priorities for oral health care services of older people in the United Kingdom and the Netherlands. A participatory setting partnership was undertaken with 4 key stakeholder groups in the United Kingdom and the Netherlands.
View Article and Find Full Text PDFMinocycline as an adjunct for treatment-resistant depressive symptoms: A pilot randomised placebo-controlled trial.
J Psychopharmacol
September 2017
6 Institute of Psychiatry, King's College London, London, UK.
Article Synopsis
- A study investigated the effects of minocycline, an anti-inflammatory medication, on patients with treatment-resistant depression when added to standard treatment over 3 months.
- The trial was double-blind and placebo-controlled, involving 41 participants, with significant improvements in depressive symptoms (measured by HAMD scores) observed in those receiving minocycline compared to the placebo group.
- The results suggest minocycline may help alleviate treatment-resistant depression symptoms, but further research is needed with a larger group to confirm these findings.*
Longitudinal Assessment of Children with Mild Cystic Fibrosis Using Hyperpolarized Gas Lung Magnetic Resonance Imaging and Lung Clearance Index.
Am J Respir Crit Care Med
February 2018
1 University of Sheffield Sheffield, United Kingdom.
Effect of accurate heart delineation on cardiac dose during the CONVERT trial.
Br J Radiol
May 2017
3 University of Manchester, Manchester Academic Health Science Centre, Institute of Cancer Sciences, Manchester, UK.
Objective: This study investigated the effect of deviation from protocol in heart delineation for the Concurrent Once-daily Versus twice-daily Radiotherapy (CONVERT) Trial ( ClinicalTrials.gov Identifier NCT00433563) quality assurance (QA) programme and the effect of that on mean cardiac dose and percentage of heart volume receiving ≥5 Gy (V) and percentage of heart volume receiving ≥30 Gy (V).
Methods: Patients with limited-stage small-cell lung cancer in the CONVERT trial were randomized to receive 45 Gy in 30# twice daily or 66 Gy in 33# once daily radiotherapy, with concurrent chemotherapy in both arms.