9 results match your criteria: "2nd affiliated hospital of Sun yat-sen University[Affiliation]"
A clinical model and nomogram for early prediction of gestational diabetes based on common maternal demographics and routine clinical parameters.
J Obstet Gynaecol Res
November 2022
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou, P.R. China.
Article Synopsis
- Developed a risk prediction model for gestational diabetes mellitus (GDM) in Chinese women using maternal demographics and clinical factors, finding a 17.2% prevalence rate among the studied population.
- The model utilized multivariable logistic regression and demonstrated good consistency and predictive ability through various statistical tests, including ROC curve analysis and cross-validation.
- A user-friendly nomogram was created for clinical practice, providing an effective tool for predicting GDM risk based on common maternal characteristics.
Cyanidin-3-o-β-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-κB Signalling.
Thromb Haemost
July 2018
Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, Guangdong Province, China.
Apoptotic-like phase is an essential step in thrombopoiesis from megakaryocytes. Anthocyanins are natural flavonoid pigments that possess a wide range of biological activities, including protection against cardiovascular diseases and induction of tumour cell apoptosis. We investigated the effects and underlying mechanisms of cyanidin-3-o-β-glucoside (Cy-3-g, the major bioactive compound in anthocyanins) on the apoptosis of human primary megakaryocytes and Meg-01 cell line in vitro We found that Cy-3-g dose-dependently increased the dissipation of the mitochondrial membrane potential, caspase-9 and caspase-3 activity in megakaryocytes from patients with newly diagnosed acute myeloid leukaemia but not in those from healthy volunteers.
View Article and Find Full Text PDFClassification and surgical management of localized attic cholesteatoma: single-institution experience and follow-up.
ORL J Otorhinolaryngol Relat Spec
September 2010
Department of Otolaryngology, 2nd Affiliated Hospital of Sun Yat-Sen University, Guangzhou, PR China.
Objectives: To present an effective system for the evaluation and surgical management of localized attic cholesteatoma, as well as describing the follow-up of patients treated at our institution.
Study Design: Retrospective review of single-institution experience.
Methods: A total of 71 patients (71 ears) with localized attic cholesteatoma received atticotomies.
Endoscope-assisted partial-superficial parotidectomy through two small skin incisions.
Acta Otolaryngol
December 2009
Department of Otorhinolaryngology & Head and Neck Surgery, 2nd Affiliated Hospital of Sun Yat-Sen University, Guangzhou, PR China.
Conclusion: Endoscope-assisted partial-superficial parotidectomy is a feasible method for treatment of benign parotid superficial lobe tumors located at the anterior or the inferior of the auricular lobule. The main advantage of this procedure is that the small operative scar resulted in improved cosmetic results.
Objectives: This study evaluated the feasibility of endoscope-assisted partial parotidectomy through two small skin incisions.
[A comparison of endoscopy-assisted and conventional partial-superficial parotidectomy].
Zhonghua Zheng Xing Wai Ke Za Zhi
July 2009
Department of Otorhinolaryngology & Head and Neck Surgery, the 2nd Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China.
Objective: To investigate the feasibility of endoscopy-assisted partial-superficial parotidectomy.
Methods: 38 cases with benign tumors located in the superficial lobe of the parotid gland were randomly assigned to receive conventional (20 cases) or endoscopic (18 cases) partial-superficial parotidectomy. Two short incisions, which were 2 to approximately 2.
A comparison between endoscope-assisted partial parotidectomy and conventional partial parotidectomy.
Otolaryngol Head Neck Surg
January 2009
Department of Otorhinolaryngology & Head and Neck Surgery, 2nd Affiliated Hospital of Sun Yat-sen University, Guangzhou, PR China.
Objective: To report the feasibility of endoscope-assisted parotidectomy with an ultrasonic scalpel.
Study Design: Randomized clinical trial.
Subjects And Methods: A total of 38 patients were randomly assigned to conventional (20 patients) or endoscope-assisted (18 patients) partial parotidectomy.
[Analysis of surgical treatment of nasopharyngeal angiofibroma].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
November 2006
Department of Otorhinolaryngology Head and Neck Surgery, 2nd Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China.
Objective: To study the individual surgical treatment of nasopharyngeal angiofibroma.
Methods: Between Feb. 1989 and Oct.
Effects of glycoprotein IIb/IIIa antagonists and chloride channel blockers on platelet cytoplasmic free calcium.
Chin Med J (Engl)
December 2005
Department of Hematology, 2nd Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510120, China.
[Effects of 2A-1-1 on the aggregation and Ca2+ influx of platelets].
Zhonghua Xue Ye Xue Za Zhi
September 2004
Department of Hematology, 2nd affiliated hospital of Sun yat-sen University, Guangzhou 510120, China.
Objective: To explore the effects of 2A-1-1 (purified component from Panax notoginsengs saponins) on the aggregation of and Ca2+ influx into human platelets.
Methods: The aggregation of platelets was tested by nephelometry, Fura-2 fluorescent technique was used for detecting cell [Ca2+]i. The effects of 2A-1-1, nifedipine and SK&F96365 on Ca(2+) influx into human platelets induced by ADP or CPA were observed separately.