4 results match your criteria: "2nd Affiliated Hospital of Zhejiang University Medical School.[Affiliation]"

Article Synopsis
  • Glioblastoma (GBM) is a highly aggressive brain cancer with high recurrence rates due to inadequate responses to traditional treatments and the presence of glioblastoma stem cells (GSCs) that contribute to therapeutic resistance.
  • GSCs exhibit unique characteristics, such as self-renewal and diverse subpopulations, making them distinct from normal neural stem cells and differentiated tumor cells.
  • Understanding the role of mitochondria in GSC metabolism and stress response mechanisms is crucial for developing novel therapies aimed at targeting these resilient cancer cells.
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Rationale: Bronchopleural fistula (BPF) is a dreaded complication after lobectomy or pneumonectomy and is associated with high morbidity and mortality. Successful management remains challenging when this condition is combined with empyema, and the initial treatment is usually conservative and endoscopic, but operative intervention may be required in refractory cases.

Patient Concerns: Two patients diagnosed with BPF with empyema were selected to undergo surgery in our hospital because they could not be cured by conservative and endoscopic therapy for 1 or more years.

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Spontaneous coronary artery rupture (SCAR) is an extremely rare, life-threatening entity without any previous underlying diseases. The clinical presentation may differ according to the site of the rupture and some patients may deteriorate early into sudden death due to the abrupt evolution of the associated cardiac tamponade and cardiogenic shock. The correct diagnosis of SCAR deserves a high level of suspicion.

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