Efficacy and aesthetic outcomes for quilting sutures in the prevention of seroma after mastectomy.

Worldwide, mastectomy for breast cancer is one of the most frequently performed surgical procedures. As one of the main complications of mastectomy, seroma is associated with pain, infections and a prolonged hospital stay. We performed a prospective multicenter randomized trial to assess the efficacy and esthetic outcomes associated with quilting the skin flap.

High-consistency proton exchange membrane fuel cells enabled by oxygen-electron mixed-pathway electrodes via digitalization design.

Proton exchange membrane (PEM) fuel cell has been regarded as a promising approach to the decarbonization and diversification of energy sources. In recent years, durability and cost issues of PEM fuel cells are increasingly significant with the rapid increase of power density. However, the failure to maintain the cell consistency, as one major cause of the above issue, has attracted little attention.

Real World Data for Pancreatic Adenocarcinoma from a Population-Based Study in France.

Pancreatic cancer is associated with high mortality rates, and most cases are diagnosed at advanced stages. This study aimed to evaluate the prognostic factors for survival in pancreatic adenocarcinoma. Data from the Finistere registry of digestive database were used in this analysis.

Radiomics Approaches for the Prediction of Pathological Complete Response after Neoadjuvant Treatment in Locally Advanced Rectal Cancer: Ready for Prime Time?

In recent years, neoadjuvant therapy of locally advanced rectal cancer has seen tremendous modifications. Adding neoadjuvant chemotherapy before or after chemoradiotherapy significantly increases loco-regional disease-free survival, negative surgical margin rates, and complete response rates. The higher complete rate is particularly clinically meaningful given the possibility of organ preservation in this specific sub-population, without compromising overall survival.

Fuzzy Model for the Automatic Recognition of Human Dendritic Cells.

Nowadays, foodborne illness is considered one of the most outgrowing diseases in the world, and studies show that its rate increases sharply each year. Foodborne illness is considered a public health problem which is caused by numerous factors, such as food intoxications, allergies, intolerances, etc. Mycotoxin is one of the food contaminants which is caused by various species of molds (or fungi), which, in turn, causes intoxications that can be chronic or acute.

[Risks and opportunities of reproduction with HIV].

As the human immunodeficiency virus (HIV) infection has become a chronic disease, the question of becoming a parent arises for HIV-positive people. There are several answers to this question, depending on the situation. Here is an overview of the risks and possibilities of procreation with HIV.

[The place of therapeutic education in the care of an HIV-positive patient].

Since the advent of triple therapy, HIV has become a chronic disease. Therapeutic patient education (TPE) seems to have a place in this accompaniment, which has sometimes lasted several decades. The role of a nurse in TPE is still essential for the accompaniment of an HIV positive patient.

[Living and aging with HIV].

HIV is not exclusive to the young population. Emotional life continues with age, and 20% of new cases of infection in France are among people over 50. This is therefore a public health issue for "seniors".

[Care and information for an HIV-positive patient].

Since the year 2000, AIDS has become a chronic disease that can be treated and monitored. The two specific and necessary parameters for monitoring patients are the CD4 lymphocyte rate, which indicates the state of the immune system, and the viral load, which makes it possible to monitor the effectiveness of the antiretroviral treatments prescribed; in addition, blood antiretroviral drugs can be measured in certain cases. Today, it is clear that a patient who is effectively treated with an undetectable viral load is no longer a contaminant and that he or she will live with the disease, while facing the health issues common to everyone: emotional life, aging, other pathologies.

[A little background on the history of AIDS and HIV].

As we have just commemorated the 40th anniversary of the discovery of AIDS, which was described in 1981 and declared a pandemic 20 years ago, in 2002, we are tracing the history of the disease in order to promote awareness of the imaginary nature of the disease. A useful approach to the care of the HIV-positive person.

Application of Plant Tissue Culture Techniques to Halophyte Species: A Review.

Halophytes are plants able to thrive in environments characterized by severe abiotic conditions, including high salinity and high light intensity, drought/flooding, and temperature fluctuations. Several species have ethnomedicinal uses, and some are currently explored as sources of food and cosmetic ingredients. Halophytes are considered important alternative cash crops to be used in sustainable saline production systems, due to their ability to grow in saline conditions where conventional glycophyte crops cannot, such as salt-affected soils and saline irrigation water.

Oxidative Stress Response's Kinetics after 60 Minutes at Different (30% or 100%) Normobaric Hyperoxia Exposures.

Oxygen is a powerful trigger for cellular reactions and is used in many pathologies, including oxidative stress. However, the effects of oxygen over time and at different partial pressures remain poorly understood. In this study, the metabolic responses of normobaric oxygen intake for 1 h to mild (30%) and high (100%) inspired fractions were investigated.

[Continued breastfeeding upon return to work: a qualitative study at the Brest University Hospital].

The objective of this qualitative study was to highlight the facilitating measures and difficulties encountered in continuing breastfeeding when returning to work at the Brest Regional University Hospital. The eleven mothers interviewed were able to take advantage of the solidarity in the care services to carry out their project, but simple institutional measures are still possible to facilitate this conciliation.

On joint parameterizations of linear and nonlinear functionals in neural networks.

The paper proposes a new class of nonlinear operators and a dual learning paradigm where optimization jointly concerns both linear convolutional weights and the parameters of these nonlinear operators. The nonlinear class proposed to perform a rich functional representation is composed by functions called rectified parametric sigmoid units. This class is constructed to benefit from the advantages of both sigmoid and rectified linear unit functions, while rejecting their respective drawbacks.

Widely-Linear Digital Self-Interference Cancellation in Full-Duplex USRP Transceiver.

Full-duplex (FD) communication systems allow for increased spectral efficiency but require effective self-interference cancellation (SIC) techniques to enable the proper reception of the signal of interest. The underlying idea of digital SIC is to estimate the self-interference (SI) channel based on the received signal and the known transmitted waveform. This is a challenging task since the SI channel involves, especially for mass-market FD transceivers, many nonlinear distortions produced by the impairments of the analog components from the receiving and transmitting chains.

Gene transfection using branched cationic amphiphilic compounds for an aerosol administration in cystic fibrosis context.

For cystic fibrosis gene therapy, the aerosolization of genetic materials is the most relevant delivery strategy to reach the airway epithelium. However, aerosolized formulations have to resist shear forces while maintaining the integrity of plasmid DNA (pDNA) during its journey from the nebulization to the epithelial cells. Herein, we compared the efficiency of gene delivery by aerosolization of two types of formulations: (i) BSV163, a branched cationic amphiphilic compound, co-formulated with different DOPE ratios (mol/mol) and DMPE-PEG5000 and (ii) 25 KDa branched polyethylenimine (b-PEI)-based formulation used as control.

[The attachment formed in addictive behaviors during the adolescent process].

At the heart of the knotting of an addiction during the adolescent process is the possibility of conceptualizing the dynamics of an addictive behavior through the prism of attachment theory. From the inheritance of a family gift, through the coloring of attachment objects, to the adolescent oedipal reactivation, the addictive behavior finds a functional echo in compensation for an inaugural lack. This lack, this deficiency from an insecure family space, conditions the appearance of a symptomatic defense embodied by the dependent attachment to external objects.

[An ethic of substitution towards an adolescent in psychological suffering].

In the light of our practice with adolescents admitted to child psychiatry, it appears that the most vulnerable among them are distinguished by their failure to request care. In resonance with a psychopathology of the link, the propensity of the professionals to substitute for it is palpable. From a phenomenological reading of the care practice and its ethical dimension, the aim is to try to confront the different components of substitution.

[Research on adolescent depression associated with parental depression].

At the crossroads of a global pandemic, here and there where public discourse misuses the concepts of depression, research has begun on a public health issue, that of adolescent depression. The Adodesp study (adolescent depression associated with parental depression) aims to study the interest of a preventive identification of adolescent depression, based on that of parental figures, while evaluating the orientation towards a care system articulated between primary care and mental health devices. To date, this study has included 42 adolescents based on the identification of 30 depressed parents.

Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression.

The goal of this study was to establish a procedure for gene delivery mediated by cationic liposomes in quiescent differentiated HepaRG™ human hepatoma cells. We first identified several cationic lipids promoting efficient gene transfer with low toxicity in actively dividing HepG2, HuH7, BC2 and progenitor HepaRG™ human hepatoma cells. The lipophosphoramidate Syn1-based nanovector, which allowed the highest transfection efficiencies of progenitor HepaRG™ cells, was next used to transfect differentiated HepaRG™ cells.

Main Causal Agents of Occupational Asthma in France, Reported to the National Network for Occupational Disease Vigilance and Prevention (RNV3P) 2001-2018.

Objectives: The definition of work-related Asthma (WRA) has changed in recent years and new etiologies and agents have been identified. The aim of this study is to describe the main causal agents of WRA in France in the period 2001-2018 in the main work sectors.

Methods: Data were collected from the French national network of occupational health surveillance and prevention [Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (RNV3P)], Data between 2001 and 2018 with at least a probable or certain association with one occupational agent, were included.

Tobacco Tax Increases: A Discourse Analysis of the French Print and Web News Media from 2000 to 2020.

Lobbying led by the tobacco industry and tobacconists is a barrier to reducing smoking prevalence in France. Here, we analyze the discourse of the tobacco industry and other key actors (public health agencies, politicians, etc.) in the French general-audience news media from 2000 to 2020 around tobacco tax increases, which is one of the most effective tobacco control measures, especially amongst youth.

Anti-Biofilm Activity of a Hyaluronan-like Exopolysaccharide from the Marine MO245 against Pathogenic Bacteria.

Biofilms, responsible for many serious drawbacks in the medical and marine environment, can grow on abiotic and biotic surfaces. Commercial anti-biofilm solutions, based on the use of biocides, are available but their use increases the risk of antibiotic resistance and environmental pollution in marine industries. There is an urgent need to work on the development of ecofriendly solutions, formulated without biocidal agents, that rely on the anti-adhesive physico-chemical properties of their materials.