Cystic neoplasms of the pancreas; what a clinician should know.

Primary cystic neoplasms of the pancreas (serous cystic neoplasms, mucinous serous neoplasms, and intraductal papillary mucinous neoplasms) are lesions of emerging importance. With the wide availability of modern imaging methods, these neoplasms are being recognized with increasing frequency. Due to the improvement of these sophisticated imaging techniques, it is often possible to differentiate preoperatively these primary pancreatic cystic neoplasms not only from other cystic pancreatic disorders (such as pancreatic pseudocysts) but also from one another.

Hepatitis caused by occupational chronic exposure to trichloroethylene.

Trichloroethylene (TCE) is an organic solvent used in a variety of industries for more than 60 years. Several adverse events following acute or chronic exposure to trichloroethylene have been reported. However, TCE-induced hepatitis is very rare.

Malignant fibrous histiocytoma of the liver: a case report and review of the literature.

Malignant fibrous histiocytoma (MFH) is a common soft tissue sarcoma, usually occurring in the extremities. MFH of the liver is an extremely rare neoplasm, with only 28 cases reported in the international literature since 1985. We present a case of MFH of the liver in an 87-year-old woman.

Lobular carcinoma in situ of the breast within a fibroadenoma. A case report.

Background: Fibroadenoma is a benign breast tumor that is effectively treated by local excision. Although uncommon, breast fibroadenoma may harbor breast carcinoma, either in situ or invasive.

Case: We present a 27-year-old woman who presented for the management of an apparently benign mass in the right breast.

Occult breast cancer: a challenge from a surgical perspective.

Patients with occult breast cancer pose a challenging diagnostic and therapeutic problem. High-quality mammography is required to decrease the false-negative rates. A number of other imaging methods have been proposed in the diagnostic evaluation of these women, including breast ultrasonography, color Doppler ultrasonography, breast magnetic resonance imaging (MRI), positron emission tomography (PET), and scintimammography.

Ductal carcinoma in situ (DCIS) of the breast: evolving perspectives.

Ductal carcinoma in situ (DCIS) of the breast is an early, localized stage of carcinoma in the process of multistep breast carcinogenesis. The incidence of DCIS is increasing, mainly due to screening mammography, which results in diagnosing the disease in an increasing proportion of asymptomatic patients. Consequently, clinicians are being confronted with growing numbers of women who present with DCIS of the breast; thus, the concepts of managing such patients are assuming greater importance.

Molecular biology of pancreatic cancer; oncogenes, tumour suppressor genes, growth factors, and their receptors from a clinical perspective.

Pancreatic cancer represents the fourth leading cause of cancer death in men and the fifth in women. Prognosis remains dismal, mainly because the diagnosis is made late in the clinical course of the disease. The need to improve the diagnosis, detection, and treatment of pancreatic cancer is great.