Municipal wastewater effluent exposure disrupts early development, larval behavior, and stress response in zebrafish.

While wastewater treatment standards have been progressively increasing, emerging contaminants such as pharmaceuticals can nonetheless pass through treatment and end up in our watersheds. Pharmaceuticals in the parts-per-billion range can impact fish behavior, survival, and recruitment in the wild. However, the ecological risk posed by whole municipal wastewater effluents (MWWE), a complex mixture, is not clear.

Twenty-five years of bis-pentafluorophenyl borane: a versatile reagent for catalyst and materials synthesis.

In 1995, the synthesis, properties and remarkable hydroboration activity of bis-pentafluorophenyl borane was first reported. Its reactivity stems from the ready accessibility of the monomeric borane and its high Lewis acidity. In the intervening twenty five years, this reagent has been widely exploited as a means of incorporating Lewis acidic -B(C6F5)2 groups into complex structures for a range of applications.

Perylene Diimide Based Organic Photovoltaics with Slot-Die Coated Active Layers from Halogen-Free Solvents in Air at Room Temperature.

Herein, we investigate the role of processing solvent additives on the formation of polymer-perylene diimide bulk-heterojunction active layers for organic photovoltaics using both spin-coating and slot-die coating methods. We compare the effect of 1,8-diiodooctane (DIO) and diphenyl ether (DPE) as solvent additives on the aggregation behavior of the non-fullerene acceptor, N-annulated perylene diimide dimer (tPDIN-EH), in neat films and blended films with the benzodithiophene-quinoxaline (BDT-QX, QX-3) donor polymer, processed from toluene in air. DIO processing crystallizes the tPDIN-EH acceptor and leads to the decreased solar cell performance.

Boron-nitrogen substituted dihydroindeno[1,2-b]fluorene derivatives as acceptors in organic solar cells.

The electrophilic borylation of 2,5-diarylpyrazines results in the formation of boron-nitrogen doped dihydroindeno[1,2-b]fluorene which can be synthesized using standard Schlenk techniques and worked up and handled readily under atmospheric conditions. Through transmetallation via diarylzinc reagents a series of derivatives were synthesized which show broad visible to near-IR light absorption profiles that highlight the versatility of this BN substituted core for use in optoelectronic devices. The synthesis is efficient, scalable and allows for tuning through changes in substituents on the planar heterocyclic core and at boron.

Additive induced crystallization of a twisted perylene diimide dimer within a polymer matrix.

The controlled aggregation of organic π-conjugated molecular semiconductors within a host material (often a polymer) is important for obtaining appropriate organic film morphologies and mechanical properties for optoelectronic applications. In this study, we demonstrate how we have challenged the twisting effect in perylene diimide dimers, which is known to hinder their aggregation. Indeed, a twisted N-annulated perylene diimide dimer (tPDI2N-EH) can be induced to form crystalline aggregates within a host poly-3-hexylthiophene (P3HT) polymer matrix using solution processing.

Molecular Simulations with in-deMon2k QM/MM, a Tutorial-Review.

deMon2k is a readily available program specialized in Density Functional Theory (DFT) simulations within the framework of Auxiliary DFT. This article is intended as a tutorial-review of the capabilities of the program for molecular simulations involving ground and excited electronic states. The program implements an additive QM/MM (quantum mechanics/molecular mechanics) module relying either on non-polarizable or polarizable force fields.

A rapid zebrafish embryo behavioral biosensor that is capable of detecting environmental β-blockers.

β-Blockers (BB) are one of the most commonly prescribed pharmaceuticals used for treating cardiovascular and acute anxiety-related disorders. This class of drugs inhibit β-adrenoceptor signalling and given their growing, widespread use, BB are routinely detected in surface waters at nM concentrations. This is concerning as trace levels of BB impart developmental and reproductive dysfunction in non-target aquatic organisms, with potential for ecological risks.

Quantitative meta-analysis of maternal prenatal salivary cortisol and newborn birthweight does not identify effect of fetal sex.

Background: Heightened concentration of maternal cortisol is a frequently proposed mechanism linking adverse maternal environments with poor birth outcomes, including birth weight. It is commonly hypothesized that prenatal exposures have sexually dimorphic effects on fetal development, however few studies have assessed the effects of fetal sex on the relationship between maternal cortisol and birth outcomes.

Methods: In a previous systematic review and meta-analysis we obtained data from authors of included studies to calculate trimester-specific correlations between maternal prenatal salivary cortisol and newborn birth weight.

"I do my best to eat while I'm using": Mapping the foodscapes of people living with HIV/AIDS who use drugs.

Food insecurity can have negative health impacts on people who use drugs and are living with HIV/AIDS (PLHIV). These include both physical effects, including poorer health outcomes and morbidity, and also behaviors that can increase the risk of physical or psychological harm. This study used a semi-structured survey of 60 PLHIV who use drugs and service access mapping (SAM) interviews of a 20-person subset.

Phosphonium-enhanced chitosan for Cr(VI) adsorption in wastewater treatment.

Adsorption is a commonly used method for industrial wastewater treatment because of its low-cost, easy operation and high efficiency. In this work, chitosan was crosslinked and functionalized with a low-cost phosphonium salt, tetrakis(hydroxymethyl)phosphonium sulfate (THPS), to enhance its adsorption capacity for Cr(VI). The novel phosphonium-crosslinked chitosan (PCC) was characterized using elemental analysis, XRF, FTIR, NMR and SEM-EDX.

On the interplay of harvesting and various diffusion strategies for spatially heterogeneous populations.

The paper explores the influence of harvesting (or culling) on the outcome of the competition of two species in a spatially heterogeneous environment. The harvesting effort is assumed to be proportional to the space-dependent intrinsic growth rate. The differences between the two populations are the diffusion strategy and the harvesting intensity.

Subject-specific and group-based running pattern classification using a single wearable sensor.

The objective of this study was to determine whether subject-specific or group-based models provided better classification accuracy to identify changes in biomechanical running gait patterns across different inclination conditions. The classification process was based on measurements from a single wearable sensor using a total of 41,780 strides from eleven recreational runners while running in real-world and uncontrolled environment. Biomechanical variables included pelvic drop, ground contact time, braking, vertical oscillation of pelvis, pelvic rotation, and cadence were recorded during running on three inclination grades: downhill, -2° to -7°; level, -0.

Fitspiration and thinspiration: a comparison across three social networking sites.

Background: Fitspiration, or images and text promoting health and fitness, and thinspiration, or images and text promoting thinness, have both received criticism for their negative effects on body image and dieting behaviors. In this study, we critically examined and compared the content of fitspiration and thinspiration on three social networking sites (SNS).

Methods: Fitspiration and thinspiration posts ( = 360) from three photo-sharing SNS (Instagram, Tumblr, and Twitter) were collected quasi-randomly on four days over two weeks.

Predictive Modeling of Energy and Emissions from Shale Gas Development.

Contributions of individual preproduction activities to overall energy use and greenhouse gas (GHG) emissions during shale gas development are not well understood nor quantified. This paper uses predictive modeling combining the physics of reservoir development operations with depositional attributes of shale gas basins to account for energy requirements and GHG emissions during shale gas well development. We focus on shale gas development from the Montney basin in Canada and account for the energy use during drilling and fluid pumping for reservoir stimulation, in addition to preproduction emissions arising from energy use and potential gas releases during operations.

Development of Nanocomposite-Based Strain Sensor with Piezoelectric and Piezoresistive Properties.

Sensors provide aninterface between mechanical systems and the physical world. With the move towardsIndustry 4.0 and cyber-physical systems, demands for cost-effective sensors are rapidly increasing.

Bioprocessing of Mesenchymal Stem Cells and Their Derivatives: Toward Cell-Free Therapeutics.

Mesenchymal stem cells (MSCs) have attracted tremendous research interest due to their ability to repair tissues and reduce inflammation when implanted into a damaged or diseased site. These therapeutic effects have been largely attributed to the collection of biomolecules they secrete (i.e.

The effects of adult depression on the recollection of adverse childhood experiences.

Adverse childhood experiences (ACEs) have been linked to numerous negative physical and mental health outcomes across the lifespan. As such, self-report questionnaires that assess for ACEs are increasingly used in healthcare settings. However, previous research has generated some concern over the reliability of retrospective reports of childhood adversity, and it has been proposed that symptoms of depression may increase recall of negative memories.

The Significance of Graphene Oxide-Polyacrylamide Interactions on the Stability and Microstructure of Oil-in-Water Emulsions.

The emulsification of oil in water by nanoparticles can be facilitated by the addition of costabilizers, such as polymers and surfactants. The enhanced properties of the resulting emulsions are usually attributed to nanoparticle/costabilizer synergy; however, the mechanism of this synergistic effect and its impacts on emulsion stability and microstructure remain unclear. Here, we study the synergistic interaction of graphene oxide (GO) and a high molecular weight anionic polyacrylamide (PAM) in stabilization of paraffin oil/water emulsion systems.

A tetrameric perylene diimide non-fullerene acceptor via unprecedented direct (hetero)arylation cross-coupling reactions.

This study reports on the synthesis of an indancenodithiophene perylene diimide tetramer via unique direct (hetero)arylation reactivity. The thiophene based core structure is shown to be easily functionalized with four perylene diimides at the four active C-H positions. This new reactivity provides a simple synthetic pathway towards tetrameric perylene diimides which have emerged as one of the best classes of electron acceptors for organic solar cells.

Mandibular shape in farmed Arctic foxes (Vulpes lagopus) exposed to persistent organic pollutants.

We investigated if dietary exposure to persistent organic pollutants (POPs) affect mandibular asymmetry and periodontal disease in paired male-siblings of Arctic foxes (Vulpes lagopus). During ontogeny, one group of siblings was exposed to the complexed POP mixture in naturally contaminated minke whale (Balaenoptere acutorostarta) blubber (n = 10), while another group was given wet feed based on pig (Sus scrofa) fat as a control (n = 11). The ∑POP concentrations were 802 ng/g ww in the whale-based feed compared to 24 ng/g ww in the control diet.

A method for deducing neck mobility in plesiosaurs, using the exceptionally preserved .

The elongate-necked aquatic plesiosaurs existed for 135 Myr during the Mesozoic. The function of this elongate neck is a point of debate. Using computed tomography and three-dimensional (3D) modelling, the range of motion (ROM) of the plesiosaur neck was assessed.

Fluorescent polycatecholamine nanostructures as a versatile probe for multiphase systems.

Shape and size controlled nanostructures are critical for nanotechnology and have versatile applications in understanding interfacial phenomena of various multi-phase systems. Facile synthesis of fluorescent nanostructures remains a challenge from conventional precursors. In this study, bio-inspired catecholamines, dopamine (DA), epinephrine (EP) and levodopa (LDA), were used as precursors and fluorescent nanostructures were synthesized a simple one pot method in a water-alcohol mixture under alkaline conditions.

How ecological processes shape the outcomes of stock enhancement and harvest regulations in recreational fisheries.

Fish stocking and harvest regulations are frequently used to maintain or enhance freshwater recreational fisheries and contribute to fish conservation. However, their relative effectiveness has rarely been systematically evaluated using quantitative models that account for key size- and density-dependent ecological processes and adaptive responses of anglers. We present an integrated model of freshwater recreational fisheries where the population dynamics of two model species affect the effort dynamics of recreational anglers.

Personality and prescription drug use/misuse among first year undergraduates.

Emerging adults (18-25 year olds) endorse the highest rates of prescription drug misuse. Attending college or university may confer additional risk. Previous research suggests that personality is an important predictor of many addictive behaviours.