Identifying 'Where' and 'How' Peer Support for Youth is Integrated into Community-Based Mental Health Services: A Survey Study.

To mitigate barriers to care among youth (12-25 years), community-based organizations have increasingly integrated peer support as a complement to clinical mental health care; however, information regarding the integration process is lacking. To explore organizational perspectives regarding the contexts and mechanisms underlying integration of peer support for youth accessing mental health services from community-based, youth-serving organizations. Representatives from community-based youth-serving organizations completed a survey describing the contexts in which they are located and their experiences integrating peer support.

CFD Analysis of Particle Dynamics in Accelerated Toroidal Systems for Enhanced PIVG Performance.

This study investigates the movements of particles in an accelerated toroidal flow channel filled with water, with specific applications for a particle imaging velocimetry gyroscope (PIVG). We used computational fluid dynamics (CFD) to simulate particle behavior under different angular accelerations. These angular accelerations were 4 rad/s, 6 rad/s, and 8 rad/s for particles densities of 1100 kg/m, 1050 kg/m, and 980 kg/m.

Experience of individuals with lung and gastrointestinal cancers undergoing radiation therapy: a qualitative study.

Purpose: Lung cancer remains one of the most diagnosed cancers in Canada and continues to be the leading cause of cancer deaths in Canada, responsible for 25% of all cancer deaths. Prior studies consistently report poor experiences of people with lung cancers. The study purpose was to explore the reasons for consistently poorer reported experience of people with lung cancer compared to people with gastrointestinal cancers, who previously have reported positive cancer care experiences within the same context, and to better understand key differences that influence patient experience.

Reliable and precise Zn isotopic analysis of biological matrices using a fully automated dual-column purification procedure.

A fully automated dual-column purification procedure for Zn from biological samples, designed for subsequent Zn isotopic analysis, is presented that utilizes the prepFAST MC™ system (Elemental Scientific), DGA resin (TrisKem International), and TK201 resin (TrisKem International). The procedure developed enables the unattended processing of 20 samples per day and is characterized by low and reproduceable blanks (< 1.5 ng), no carry-over or memory effect, high reusability (> 50 times), high Zn yields 100.

Quantitative Measurement of Individual and Contextual Determinants of COVID-19 Vaccination in General Population Samples: A Scoping Review.

Background: This scoping review aims to map the quantitative literature investigating vaccine-related individual and contextual determinants of COVID-19 vaccination uptake, identify and define constructs assessed, and describe the characteristics of self-report measures.

Methods: A systematic search of electronic databases was conducted to capture peer-reviewed journal articles published between December 31, 2019, and December 25, 2021. Studies conducted in English and collecting data from general population samples using self-report measures of vaccine-related determinants of COVID-19 vaccination behavior were eligible.

Molecular Interactions and Responsive Locations of CO-Responsive Surfactants in an Oil-Water-Surfactant System: Molecular Dynamics Simulation and Free Energy Perturbation.

Understanding the mechanism of a CO-responsive surfactant is essential for enhancing its industrial applications. Conventional experimental methods face challenges in pinpointing the exact location of proton transfer within the system and in accurately describing the impact of intermolecular and intramolecular interactions on the CO responsiveness of such substances. To address this gap, this study employs molecular dynamics simulations and free energy perturbation methods to investigate the proton transfer process between a CO-responsive cationic surfactant '-dodecyl-,-dimethylacetamidinium (DMAAH) and its counterion bicarbonate ion at the oil-water interface and micelle surface and in the bulk aqueous phase.

Development of a Machine Learning Tool to Predict Deep Inspiration Breath Hold Requirement for Locoregional Right-Sided Breast Radiation Therapy Patients.

This study presents machine learning (ML) models that predict if deep inspiration breath hold (DIBH) is needed based on lung dose in right-sided breast cancer patients during the initial computed tomography (CT) appointment. Materials and methods. Anatomic distances were extracted from a single-institution dataset of free breathing (FB) CT scans from locoregional right-sided breast cancer patients.

Intramolecular Csp-H Activation at a Platinum(IV) Center Resulting from O Activation: The Role of a Proton-Responsive Ligand and Trans Influence.

Aerobic oxidation of a dimethylplatinum(II) complex featuring 1,1-di(2-pyridyl)ethanol as a supporting ligand leads to the formation of two unexpected Pt complexes (in ∼1:1 ratio), neither of which results from direct oxidation typical for Pt centers supported by popular κ-(,) ligands. While one product features an isomerized Pt center stabilized by the κ-(,,) ligand coordination mode, surprisingly, the other product results from intramolecular activation of the ligand methyl fragment. Mechanistic studies, reactivity of model complexes, and DFT calculations reveal that the critical proton-responsive nature of the ligand allows formation of intermediates that result in a concerted metalation deprotonation (CMD)-like C-H activation at Pt.

An endpoint adjudication committee for the assessment of computed tomography scans in fracture healing.

Introduction: Endpoint Adjudication Committees (EACs) benefit the quality of randomized control trials (RCTs) where outcomes depend on subjective interpretations. However, assembling a committee to adjudicate large datasets is cumbersome. In a recent RCT, the primary outcome was time to union following operative fixation of scaphoid non-union, with real or placebo adjunctive ultrasound treatment.

A Hypoxia-Inflammation Cycle and Multiple Sclerosis: Mechanisms and Therapeutic Implications.

Purpose Of Review: Multiple sclerosis (MS) is a complex neurodegenerative disease characterized by inflammation, demyelination, and neurodegeneration. Significant hypoxia exists in brain of people with MS (pwMS), likely contributing to inflammatory, neurodegenerative, and vascular impairments. In this review, we explore the concept of a negative feedback loop between hypoxia and inflammation, discussing its potential role in disease progression based on evidence of hypoxia, and its implications for therapeutic targets.

Feminist understandings of newcomer women's embodiment.

In recent years, numerous scholars have advocated for the concept of embodiment-defined as the experience of engaging one's body with the world (Allan, 2005; Piran & Teall, 2012)-as a valuable framework for understanding women's experiences of their bodies. However, there is a paucity of research on embodiment specifically among newcomer women (including immigrants, refugees, and non-permanent residents) who belong to racialized groups in Canada. This article presents findings from a feminist research study employing an Arts-Based Engagement Ethnography (ABEE) methodology to investigate the embodiment experiences of six racialized newcomer women in Canada.

Quality indicators for schizophrenia care: A scoping review.

Measuring quality of care is a critical first step towards improving the healthcare contributing to persistent poor outcomes experienced by many people living with schizophrenia. This scoping review aims to identify and characterize indicators for measuring the quality of care for people living with schizophrenia. We searched 6 academic databases, 4 grey literature databases, and 23 organization websites for documents containing quality indicators developed for or applied in a population with schizophrenia-spectrum disorders.

Controls on regional sulphate distribution in shallow groundwater in the western Canadian Interior Plains.

Sulphate (SO), predominantly derived from sulphur (S)-bearing glacial sediments distributed widely across the Canadian Interior Plains, contributes to high groundwater salinity and can be detrimental to riparian and dry-land ecosystems, agricultural production, and water use. While previous researchers investigated SO distribution and dynamics in shallow groundwater at local scales (<1500 km), we examine SO occurrence in groundwater at larger scales, and to depths of ∼150 m, considering variations in geology, glacial history, climate, and geochemical and hydrogeological settings in the Canadian province of Alberta. Sulphate concentrations in groundwater vary considerably, with 15 % of 139,130 samples above the 500 mg/L Canadian drinking water aesthetic objective.

A parallel compositional reservoir simulator for large-scale CO geological storage modeling and assessment.

Storing CO in deep aquifers and depleted gas reservoirs is an effective way to achieve carbon neutrality. However, the numerical simulation of CO storage in these formations is challenging due to the complexity of gases-brine systems. The number of gas species included in the gases-brine fluid models of existing simulators cannot meet the rapidly evolving CO sequestration scenarios.

Accessing Homo- and Heterobimetallic Complexes with a Dianionic Pentadentate Ligand.

The tetrapyrazolylpyridyl diborate (BPzPy) ligand provides a suitable platform for the isolation of heterobimetallic main-group element compounds as well as homotetrametallic copper complexes. The heterobimetallic tin(II)-lithium(I) () and tin(II)-thallium(I) () complexes have been synthesized, isolated, and fully characterized including single-crystal X-ray diffraction analysis. When reacted with copper(I) sources, complex grants access to a homotetrametallic copper(I) complex ().

Key Considerations in Integrating a Peer Support Model Within Psychiatric Emergency Services at a Canadian Pediatric Emergency Department: A Qualitative Study.

Difficulties accessing primary care and community-based mental health supports has contributed to youth (aged < 18 years) with mental health concerns presenting to Emergency Departments (EDs). Peer support services in community-based mental health settings are associated with improved outcomes; research exploring this in pediatric EDs is lacking. Determine feasibility and acceptability of integrating peer support services into a pediatric ED.

"Give me the reigns of taking care of myself with a home": Healing environments in an Indigenous-led alcohol harm reduction program.

Background: Distinct from western Managed Alcohol Programs (MAPs), Indigenous-led alcohol harm reduction programs can be defined by both 'culture as healing' and decolonized harm reduction philosophies. We sought to explore experiences of Indigenous 'family members' (participants) in an Indigenous-led alcohol harm reduction program and culturally supportive housing to identify appropriate supports according to family member perspectives, and to inform delivery of the program.

Methods: Situated within an Indigenous-western research partnership, we completed semi-structured interviews with seven family members of an Indigenous-led alcohol harm reduction and culturally supportive housing program.

Influence of Mixed Solvent in the Morphology and Hydrophobicity of Electrospun Polystyrene Porous Fibers.

Electrospun polystyrene (PS) fibers are produced using a mixed solvent of chloroform and n,n-dimethylformamide (DMF) to investigate the influence of the solvent ratio on the fiber surface morphology and contact angle of the obtained mats. Electrospinning is a simple processing technique for producing fibers with diameters in the range of nanometers to a few micrometers. When using the different solvent ratios for this process, porous PS membranes are created due to nonsolvent and thermally induced phase separation (N-TIPS).

Contributions and future potential of animal models for geroscience research on sensory systems.

Sensory systems mediate our social interactions, food intake, livelihoods, and other essential daily functions. Age-related decline and disease in sensory systems pose a significant challenge to healthy aging. Research on sensory decline in humans is informative but can often be difficult, subject to sampling bias, and influenced by environmental variation.

Tracing early pastoralism in Central Europe using sedimentary ancient DNA.

Central European forests have been shaped by complex human interactions throughout the Holocene, with significant changes following the introduction of domesticated animals in the Neolithic (∼7.5-6.0 ka before present [BP]).

The influence of education in predicting conversion from Subjective cognitive decline (SCD) to objective cognitive impairment: A systematic review and meta-analysis.

Background: Subjective cognitive decline (SCD) is considered a pre-symptomatic stage of dementia characterized by cognitive complaints. The ability of education to reduce the risk of dementia is well known. Our objective is to investigate the influence of education on the risk of progression from SCD to MCI or dementia.