1 results match your criteria: "2300 RA Leiden (The Netherlands). ijzerman@lacdr.leidenuniv.nl.[Affiliation]"
ChemMedChem
July 2015
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, P.O. Box 9502, 2300 RA Leiden (The Netherlands).
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy. We previously described a new approach for the design of CCR2 antagonists by the use of structure-kinetics relationships (SKRs).
View Article and Find Full Text PDF© LitMetric 2025. All rights reserved.