54 results match your criteria: "2227. Cidade Universitaria[Affiliation]"

Selective outcome reporting concerning antibiotics and third molar surgery.

Clin Oral Investig

January 2025

Department of Oral and Maxillofacial Surgery, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, 05508-000, Brazil.

Objectives: This study evaluates the selective outcome reporting (SOR) in clinical trials on antibiotic use in third molar surgeries. It explores how SOR may bias results and affect systematic reviews, potentially leading to misinterpretations of intervention efficacy.

Materials And Methods: A search was conducted on "ClinicalTrials.

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Comparison between PCR-RFLP and sequencing techniques in the analysis of Paracoccidioides spp. biodiversity: limitations and insights into species and variant differentiation.

Mycopathologia

November 2024

Laboratório de Investigação Médica em Micologia (LIM53), Instituto de Medicina Tropical de São Paulo, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Éneas de Carvalho Aguiar n470, Cerqueira Cézar, São Paulo, SP, 05403000, Brazil.

Background: The study of Paracoccidioides spp. faces significant challenges due to limitations inherent in the molecular biology techniques employed. Recently, new species were described whose geographical and genetic distributions were investigated.

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Article Synopsis
  • A case study of a 16-year-old girl with a four-year-old nodule on her tongue illustrates the tumor's characteristics, which included myxoid and chondroid features confirmed through surgical excision and histopathological analysis.
  • The tumor's immunohistochemical markers (GFAP and S-100 proteins) helped confirm the diagnosis, and after five years, the patient showed no signs of tumor recurrence, highlighting the importance of recognizing this distinctive tumor to prevent misdiagnosis.
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Objective: To assess the diagnostic validity of ICDAS clinical criteria on 3D dental models from intraoral scanning.

Methods: This is a retrospective analysis on part of the baseline sample collected in a cohort study and included 73 participants (12-19 years) from Denmark and Greece. The assessment was made by visual inspection, and then by visual inspection associated with radiographs.

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Postoperative nausea and vomiting in orthognathic surgery: systematic review and meta-analysis.

Oral Maxillofac Surg

September 2024

Department of Oral & Maxillofacial Surgery, Traumatology and Prosthesis, Faculty of Dentistry, University of São Paulo, São Paulo, SP, Brazil.

Purpose: Postoperative nausea and vomiting (PONV) is a frequently reported adverse event following orthognathic surgery. The aim of this work is to conduct a systematic review of the literature on the subject, and to discuss the role of maxillofacial surgeons and the steps that can be taken to prevent or control PONV in orthognathic surgery.

Methods: A systematic review was conducted according to the PRISMA guidelines, using the search strategy: (orthognathic AND (nausea OR vomiting)).

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The differentiation between ameloblastoma (AB) and odontogenic keratocyst (OKC) is essential for the formulation of the surgical plan, especially considering the biological behavior of these two pathological entities. Therefore, developing means to increase the accuracy of the diagnostic process is extremely important for a safe treatment. The aim of this study was to use magnetic resonance imaging (MRI) based on texture analysis (TA) as an aid in differentiating AB from OKC.

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Advances in Ceramics for Dental Applications.

Dent Clin North Am

October 2022

Department of Biomaterials and Oral Biology, University of São Paulo - USP. Av Prof Lineu Prestes, 2227. Cidade Universitária, São Paulo, São Paulo 05508-000, Brazil.

The purpose of this study is to present current dental ceramic materials and processing methods. The clinical indication was emphasized on basis of the material's microstructure and composition. Studies of ceramic characterization were also discussed, as they impact the clinical indication and serve as a parameter for the development of new materials.

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Two-Year Survival of Ceramic Endocrowns and Partial Coverage Ceramic Restorations with Fiber Post: A 2-Year Double-Blind Randomized Clinical Trial.

Eur J Prosthodont Restor Dent

November 2022

Associate Professor, School of Dentistry, University of São Paulo (USP), Av. Prof lineu Prestes, 2227. Cidade Universitaria, São Paulo, Brazil.

Purpose: This double-blind randomized clinical trial (RCT) aimed to evaluate the 2-year survival rates of endocrowns and partial coverage ceramic restorations (PCCR) with fiber posts.

Material And Methods: Forty (40) participants fulfilled the elegibility criteria, and they were randomly allocated in 2 groups: Endocrown or PCCR+post. The survival rates were assessed based on USPHS modified and radiographic examinations.

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Nitrogenous compounds in the saliva and blood of cirrhotic patients: a cross-sectional study.

Clin Oral Investig

June 2022

Department of Stomatology, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, São Paulo, 05508-000, Brazil.

Objectives: Serum increase of nitrogenous compounds (NC) in cirrhotic patients has been associated with the development of hepatic encephalopathy (HE). However, the relation between NC in saliva and HE is unclear. The objective of this study is to measure the levels of nitric oxide and urea in the blood and saliva in 38 cirrhotic patients and correlate them with clinical characteristics and presence and grades of HE.

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Management of orofacial lesions with antimicrobial photodynamic therapy and photobiomodulation protocols in patients with COVID-19: A multicenter case series.

Photodiagnosis Photodyn Ther

June 2022

Department of Biomaterials and Oral Biology, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP 05508-900, Brazil. Electronic address:

Several oral lesions related to COVID-19 have been described in the scientific literature. The COVID-19 pandemic highlighs importance of supportive protocols, which can reduce the inflammation and aid in tissue repair in severe cases. Photobiomodulation therapy (PBMT) alone or in combination with antimicrobial photodynamic therapy (aPDT) can be used to manage orofacial lesions in confirmed cases of COVID-19.

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Hesperidin reduces dentin wear after erosion and erosion/abrasion cycling in vitro.

Arch Oral Biol

September 2021

Department of Restorative Dentistry, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Rua Monsenhor Furtado, s/nº, Fortaleza, CE, Brazil. Electronic address:

Objective: To evaluate the action of hesperidin (HPN) at different concentrations to prevent dentin erosive wear, associated or not to abrasion.

Methods: A study with 6 experimental groups (n = 10) for erosion (experiment 1) and another 6 for erosion + abrasion (experiment 2). The treatments were: distilled water (DW), DW with collagenase (DW + Col), 0.

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In situ evaluation of desensitizing toothpastes for protecting against erosive tooth wear and its characterization.

Clin Oral Investig

December 2021

Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 Cidade Universitária, São Paulo, SP, 05508-000, Brazil.

Objective: This five-phase, single-blind, crossover in situ trial evaluated the effects of desensitizing or anti-erosive toothpastes on dentin erosive wear and tubule occlusion.

Materials And Methods: Some characteristics such as relative dentin abrasivity (RDA), viscosity (V), cytotoxicity, and fluoride and calcium (Ca) availability of the toothpastes were also tested. Samples were positioned on removable intraoral appliances from 15 volunteers (n=4), according to the groups, C-control (0 ppm fluoride), F-sodium monofluorophosphate (MFP), A-MFP and arginine+calcium carbonate, CSP-calcium sodium phosphosilicate, and CS-MFP and calcium silicate+sodium phosphate.

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The aim of this in vitro study was to evaluate the protective effect of short-pulsed CO 9.3 μm laser irradiation against erosion in human enamel without and combined with TiF and AmF/NaF/SnCl applications, respectively, as well as compared to the protective effect of these fluoride treatments alone. After polishing, ninety enamel samples (3 × 3mm) were used for 9 different treatment groups: 4% TiF gel (pH 1.

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Can immunohistochemical biomarkers distinguish epithelial dysplasia degrees in actinic cheilitis? A systematic review and meta-analysis.

Med Oral Patol Oral Cir Bucal

January 2020

School of Dentistry, Department of Oral Pathology University of São Paulo, Av. Lineu Prestes, 2227 Cidade Universitária, São Paulo, SP 05508-000, Brazil

Background: Actinic cheilitis (AC) is a potentially malignant disorder of the lip, characterized by epithelial and connective tissue alterations caused by chronic exposure to ultraviolet radiation. In the past decades, diverse studies have been conducted in lip carcinogenesis and many biomarkers have been identified in lip lesions, yet there is no scientific evidence that determines its usefulness in the clinical setting or in histopathological routine. Therefore, we conducted the first systematic review in this field to summarize the results of published studies on immunohistochemical biomarkers in lip carcinogenesis, to evaluate if there is a marker than can distinguish the different histological grades of AC.

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Enamel surface loss after erosive and abrasive cycling with different periods of immersion in human saliva.

Arch Oral Biol

January 2020

Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 Cidade Universitária, São Paulo, 05508-000, SP, Brazil. Electronic address:

Objective: This in vitro study aimed to evaluate different periods of exposure to clarified human saliva for the ability to protect enamel against erosive tooth wear.

Methods: For this purpose, sixty specimens (4 × 4 × 1.5 mm) were prepared from third human molars.

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Purpose: The aim of this study was to characterize the taste changes and taste bud atrophy observed in the period of neutropenia of HCT and to determine the influence of transplantation toxicity on these changes.

Methods: Autologous and allogeneic HCT patients (n = 51) were selected to perform taste acuity tests prior to conditioning (T0) and during neutropenia (T1). The frequency and time duration of oral mucositis, presence of tongue depapillation, and salivary flow rate were also evaluated.

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Purpose: The aim of this study was to evaluate if health and oral health status of children and adolescents with different stages of CKD are associated with their health-related quality of life (HRQoL), oral health-related quality of life (OHRQoL) and socioeconomic and demographic conditions.

Methods: One hundred children and adolescents with CKD were age and gender matched to 100 individuals without CKD (mean age ± SD = 13.04 ± 2.

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This study aimed to evaluate microhardness of a dentifrice containing fluoride and arginine compared to a positive control (fluoride only) and a negative control (no fluoride) on sound and demineralized bovine enamel surfaces. Specimens were randomly assigned to different treatments that included daily pH cycling and brushing three times a day with one of the following dentifrices ( = 8): Neutraçucar (arginine and fluoride), Colgate Total 12 (fluoride) and My First Colgate (no fluoride). Enamel carious lesions were artificially created one week before the beginning of these treatments (demineralized bovine enamel (DE) groups).

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Incidental finding of subgemmal neurogenous plaque upon retrospective evaluation of oral lymphoepithelial cysts.

Oral Maxillofac Surg

December 2018

Oral and Maxillofacial Pathology Department, School of Dentistry-University of São Paulo, Av. Professor Lineu Prestes, 2227 Cidade Universitária, São Paulo, SP, 05508-000, Brazil.

Purpose: We aimed to compare the histomorphological features of oral lymphoepithelial cysts (OLC) in different locations of the oral cavity and to verify the association between oral lymphoepithelial cysts and subgemmal neurogenous plaque (SNP) on biopsies from the lateral border of the tongue.

Methods: All cases diagnosed as OLC from the Oral Pathology Service at the School of Dentistry/University of São Paulo were retrieved. For all the cysts located in the tongue, their association to SNP was analyzed.

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Objective: The 4-nitroquinoline 1-oxide (4-NQO) model for carcinogenesis has been used to investigate cancer stem cells (CSC), but no study has addressed the role of the p75 neurotrophin receptor (p75) in 4-NQO-induced oral dysplasia and oral squamous cell carcinoma (OSCC). The aim of this study was to evaluate the immunohistochemistry profile of the p75 during 4-NQO-induced oral carcinogenesis in rats and to verify whether this profile has an association with proliferating cell nuclear antigen (PCNA) immunolabeling.

Design: For 28 weeks, rats were exposed to 4-NQO, which was diluted in the drinking water.

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Busulfan is a major component of chemotherapy conditioning in hematopoietic cell transplantation (HCT). This alkylating agent is highly toxic at myeloablative doses, exposing HCT patients to risks of mortality. Non-myeloablative (NMA) and reduced-intensity conditioning (RIC) using busulfan have shown impaired toxicity.

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Immunohistochemical analysis of BRAF V600E mutation in ameloblastomas.

Clin Oral Investig

February 2019

Department of Stomatology, Division of General Pathology, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, Brazil.

Objective: This study aimed to investigate the presence of BRAF V600E mutation in mandible ameloblastomas by correlating clinical and imaging data on the cases studied.

Methods: Eighty-four cases diagnosed as mandibular ameloblastoma were selected for analysis. The specimens were submitted to immunohistochemistry for detection of BRAF V600E mutated protein.

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Purpose: The purpose of this study was to evaluate the behavior of mandibular canines acting as abutment teeth and indirect retainers of a Kennedy class II according to different designs: lingual rest and lingual rest associated with a reciprocal arm.

Materials & Methods: A resin cast with two simulated canine teeth was made in Ni-Cr alloy, representing a Kennedy class II mandibular arch. With the objective of simulating the resilience of the periodontal ligament, a polyurethane layer was added at the canine tooth's root.

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Some members of aquaporin family (AQP) plays crucial functions in salivary synthesis and secretion. These proteins expression has already been reported during salivary gland formation, however no previous studies in human developing glands have been performed. We evaluated AQP1, 3 and 5 expression through the stages of human salivary gland morphogenesis and discuss the possible role of AQP for glandular maturation.

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Oral shedding of human herpesviruses in renal transplant recipients.

Clin Oral Investig

March 2018

Division of Pathology, Department of Stomatology, University of São Paulo School of Dentistry, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, Brazil.

Objective: To describe the shedding profile of human herpesviruses in the saliva of renal transplant recipients.

Methods: This is a prospective case-control study of 50 renal transplant recipients and control group of 50 individuals (non-transplanted and immunocompetent). Mouthwash samples were collected via oral rinse and then submitted to screening for the presence of eight types of herpesviruses by using multiplex PCR.

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