Impact of abortion law reforms on health services and health outcomes in low- and middle-income countries: a systematic review.

While restrictive abortion laws still prevail in most low- and middle-income countries (LMICs), many countries have reformed their abortion laws, expanding the grounds on which abortion can be performed legally. However, the implications of these reforms on women's access to and use of health services, as well as their health outcomes, are uncertain. This systematic review aimed to evaluate and synthesize empirical research evidence concerning the effects of abortion law reforms on women's health services and health outcomes in LMICs.

Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model.

Background Context: Chronic low back pain (LBP) is a multifactorial disorder with complex underlying mechanisms, including associations with intervertebral disc (IVD) degeneration in some individuals. It has been demonstrated that epigenetic processes are involved in the pathology of IVD degeneration. Epigenetics refers to several mechanisms, including DNA methylation, that have the ability to change gene expression without inducing any change in the underlying DNA sequence.

Mast cell stabilizer ketotifen fumarate reverses inflammatory but not neuropathic-induced mechanical pain in mice.

Introduction: Mast cell (MC) activation could establish a positive feedback loop that perpetuates inflammation and maintains pain. Stabilizing MCs with ketotifen fumarate (KF) may disrupt this loop and relieve pain.

Objective: We aimed to test the effect of treatment with KF in pain assays in mice and in a case series of patients with chronic widespread pain.

Associations between lifetime stress exposure and the error-related negativity (ERN) differ based on stressor characteristics and exposure timing in young adults.

Life stress increases risk for multiple forms of psychopathology, in part by altering neural processes involved in performance monitoring. However, the ways in which these stress-cognition effects are influenced by the specific timing and types of life stressors experienced remains poorly understood. To address this gap, we examined how different social-psychological characteristics and developmental timing of stressors are related to the error-related negativity (ERN), a negative-going deflection in the event-related potential (ERP) waveform that is observed from 0 to 100 ms following error commission.

Global Least Squares Path Modeling: A Full-Information Alternative to Partial Least Squares Path Modeling.

Partial least squares path modeling has been widely used for component-based structural equation modeling, where constructs are represented by weighted composites or components of observed variables. This approach remains a limited-information method that carries out two separate stages sequentially to estimate parameters (component weights, loadings, and path coefficients), indicating that it has no single optimization criterion for estimating the parameters at once. In general, limited-information methods are known to provide less efficient parameter estimates than full-information ones.

Detection of Fusobaterium nucleatum in feces and colorectal mucosa as a risk factor for colorectal cancer: a systematic review and meta-analysis.

Background: Colorectal cancer (CRC) is a major cause of cancer deaths worldwide. Accumulating evidence suggests a potentially important role of colorectal infection with Fusobacterium nucleatum (F. nucleatum) in colorectal carcinogenesis.

The impact of encoding scenarios on different forms of temporal order memory.

This study investigated the impact of encoding scenarios on sequential memory, specifcally testing the benefit of imagining a spatial context when learning a list of items. In Experiment 1, participants studied sequences of visually presented items after imagining a spatial context or a preparatory cue. At test, participants made recency judgments (Which came first?) on pairs of items from the studied sequences.

Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study.

Introduction: No studies have reported mental health symptom comparisons prior to and during COVID-19 in vulnerable medical populations.

Objective: To compare anxiety and depression symptoms among people with a pre-existing medical condition and factors associated with changes.

Methods: Pre-COVID-19 Scleroderma Patient-centered Intervention Network Cohort data were linked to COVID-19 data from April 2020.

Something old, something new: A review of the literature on sleep-related lexicalization of novel words in adults.

Word learning is a crucial aspect of human development that depends on the formation and consolidation of novel memory traces. In this paper, we critically review the behavioural research on sleep-related lexicalization of novel words in healthy young adult speakers. We first describe human memory systems, the processes underlying memory consolidation, then we describe the complementary learning systems account of memory consolidation.

CD38 is associated with communal behavior, partner perceptions, affect and relationship adjustment in romantic relationships.

Given the significance of close relationships for human survival, it is thought that biological mechanisms evolved to support their initiation and maintenance. The neuropeptide oxytocin is one such candidate identified in non-human animal research. We investigated whether variation in CD38, a gene involved in oxytocin secretion and attachment behavior in rodents, predicts romantic relationship dynamics in daily life.

Comparing the effects of different methodological decisions on the error-related negativity and its association with behaviour and gender.

The error-related negativity (ERN) is an event-related potential (ERP) component that is widely used to study human performance monitoring. However, substantial methodological differences exist across studies and it is unclear to what extent these differences may impact the reliability and replicability of observed effects. The current study used multiple common methodological approaches to ERN measurement on the same dataset in order to clarify the impact of these choices on the component's measured amplitude, psychometric properties, and association with individual differences, specifically behaviour and gender.

Developmental trajectories to reduced activation of positive valence systems: A review of biological and environmental contributions.

Reduced activation of positive valence systems (PVS), including blunted neural and physiological responses to pleasant stimuli and rewards, has been shown to prospectively predict the development of psychopathology. Yet, little is known about how reduced PVS activation emerges across development or what implications it has for prevention. We review genetic, temperament, parenting, and naturalistic and laboratory stress research on neural measures of PVS and outline developmentally-informed models of trajectories of PVS activation.

The relation between perceived injustice and symptom severity in individuals with major depression: A cross-lagged panel study.

Background: Perceived injustice has been associated with problematic recovery outcomes in individuals with debilitating health conditions. However, the relation between perceived injustice and recovery outcomes has not been previously examined in individuals with debilitating mental health conditions. The present study examined the relation between perceived injustice and symptom severity in individuals undergoing treatment for Major Depressive Disorder (MDD).

Towards a biopsychosocial approach in dentistry: the Montreal-Toulouse Model.

The biomedical model has been severely criticised in the last decades and its dominance challenged. This is why the concept of person-centred dentistry has penetrated the professional discourse and become a growing concern for our profession. Furthermore, dentists have been urged to take patients' environment more into account and to tackle the social determinants of their health, illness and access to care.

Sensorimotor adaptation across the speech production workspace in response to a palatal perturbation.

Talkers have been shown to adapt the production of multiple vowel sounds simultaneously in response to altered auditory feedback. The present study extends this work by exploring the adaptation of speech production to a physical alteration of the vocal tract involving a palatal prosthesis that impacts both somatosensory and auditory feedback during the production of a range of consonants and vowels. Acoustic and kinematic measures of the tongue were used to examine the impact of the physical perturbation across the various speech sounds, and to assess learned changes following 20 min of speech practice involving the production of complex, variable sentences.

Opioid receptor blockade inhibits self-disclosure during a closeness-building social interaction.

Social ties are critical to human health and well-being; thus, it is important to gain a better understanding of the neurobiological mechanisms involved in the development of interpersonal closeness. Prior research indicates that endogenous opioids may play a role in social affiliation by elaborating feelings of social connection and warmth; however, it is not currently known whether opioids mediate affiliative behavior and emerging feelings of closeness in humans at the relationship initiation stage. This randomized, double-blind study examined opioidergic processes in the context of a naturalistic, face-to-face social interaction.

Adaptive and selective production of syllable duration and fundamental frequency as word segmentation cues by French-English bilinguals.

Despite the significant impact of prosody on L2 speakers' intelligibility, few studies have examined the production of prosodic cues associated with word segmentation in non-native or non-dominant languages. Here, 62 French-English bilingual adults, who varied in L1 (French or English) and language dominance, produced sentences built around syllable strings that can be produced either as one bisyllabic word or two monosyllabic words. Each participant produced both English and French utterances, providing both native productions (used as reference) and L2 productions.

Development and evaluation of an online infertility peer supporter training program.

Objective: To outline the development and evaluation of an online infertility peer supporter training program.

Methods: Men and women with diverse infertility backgrounds were recruited and trained to provide online peer support to people undergoing fertility treatment. Training required volunteers to (1) read a peer support training manual, (2) watch a webinar, and (3) complete practice questions, each of which was evidence-based and reviewed by key stakeholders.

Developing a Japanese version of the Injustice Experience Questionnaire-chronic and the contribution of perceived injustice to severity of menstrual pain: a web-based cross-sectional study.

Background: Menstrual pain causes low quality of life among women of reproductive age, and often interferes with daily activities. Perceived injustice is a cognition linked to adverse symptoms. The aims of this study were to develop a Japanese version of the Injustice Experience Questionnaire-chronic (IEQ-chr-J), and to examine if perceived injustice is associated with pain intensity and impairment from menstruation.

Episodic memory contributions to autobiographical memory and open-ended problem-solving specificity in younger and older adults.

Research indicates that episodic memory processes are required to access specific autobiographical events and the details encompassed by a single event for several functions, including remembering and personal problem solving. Since healthy cognitive aging is associated with episodic memory decline, we hypothesized that older adults would be impaired at producing specific autobiographical events and details in service of these two functions. To test this hypothesis, younger and older adults completed two tasks (generation and elaboration) across two experiments (autobiographical memory and problem solving).

Is a fusobacterium nucleatum infection in the colon a risk factor for colorectal cancer?: a systematic review and meta-analysis protocol.

Background: Despite a considerable amount of epidemiological research for identification of risk factors involved in the development of colorectal cancer, the current understanding of the etiology of this disease remains rather poor. Accumulating evidence suggests a potentially important role of infection with Fusobacterium nucleatum in the colon in colorectal carcinogenesis. The objective of this systematic review is to synthesize the epidemiological evidence on the association between infection with Fusobacterium nucleatum in the colon and colorectal cancer.

Correction to: Acetylcholinesterase inhibitors and the risk of osteoporotic fractures: nested case-control study.

Please find below the correction for the paragraph under the Heading "Materials and methods - Regulatory approval".