13 results match your criteria: "2 University of Louisville[Affiliation]"

Background:: Lesser toe plantar plate attenuation or disruption is being increasingly implicated in a variety of common clinical conditions. A multitude of surgical techniques and devices have been recently developed to facilitate surgical repair of the plantar plate. However, the microvascular anatomy, and therefore the healing potential in large part, has not been defined.

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This article aims to describe a rare cause of severe encephalitis in 2 cases of infants with signs of intracranial hypertension and severe autonomic dysregulation. The authors conclude that human parechoviruses are becoming a more recognized cause of encephalitis because of the increasing use of rapid detection methods. With early recognition of this clinical entity, improved care can be administered.

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Background: More radon-related lung cancers occur among those exposed to tobacco smoke.

Objectives: To test the effects of a personalized environmental report back intervention on change in stage of action for air nicotine testing and adopting a smoke-free home and radon testing and mitigation from baseline to 3 months postintervention.

Methods: The study design used a two-arm parallel groups randomized controlled trial with stratified quota sampling.

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Psychotropic Polypharmacy Among Children and Youth Receiving Medicaid, 2012-2015.

J Manag Care Spec Pharm

August 2018

1 University of Louisville, School of Medicine, Department of Pediatrics, Child and Adolescent Health Research Design and Support (CAHRDS), Louisville, Kentucky.

Background: The rates of mental health diagnoses in children have increased. Children in poverty have the highest rates. The use of psychotropic medication for children has been increasing, which is concerning because of the unknown long-term effects and the increased burden on the health care system.

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Introduction Monoclonal antibodies possess unique pharmacokinetic properties that permit flexible dosing. Increased use and high costs of these medications have led to the development of cost-containing strategies. This study aims to quantify the cost savings and clinical impact associated with dose rounding monoclonal antibodies to the nearest vial size.

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Objective: Although several studies suggest that religious involvement tends to favor healthy biological functioning, most of this work has been conducted in the United States. This study explores the association between religious participation and biological functioning in Mexico.

Method: The data are drawn from two waves of the Mexican Health and Aging Study (2003-2012) to assess continuous and categorical biomarker specifications.

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Long and complicated grief is a relevant factor contributing to the deterioration of the older adults' later life quality. In China, the unintentional consequence of the one-child policy has emerged. There, the group of older adults who lost their only child is called shiduers.

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Early childhood is an important period for development. Parents play an important role in structuring children's physical and psychosocial environments. Much remains unknown about the best methods for engaging parents in health promotion programs.

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This article analyzed how sexual satisfaction, suffering, severity and impact of urinary incontinence, and psychological morbidity affected women's quality of life and whether suffering mediated the relationship between psychological morbidity and quality of life. The study included 80 women diagnosed with urinary incontinence receiving rehabilitation treatment. Regression analysis showed that sexual satisfaction, suffering, and urinary incontinence severity and impact predicted quality of life and that suffering mediated the relationship between psychological morbidity and quality of life.

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Despite the potential value of DNA evidence for criminal investigations and prosecution, we have a limited understanding of the way forensic evidence is used and its impact on case outcomes. This study uses qualitative data to describe the way investigators from the Houston Police Department use DNA evidence during investigations of sexual assaults. Results show DNA evidence has limited influence during investigations, and the value of DNA evidence is shaped by other evidentiary factors.

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This integrative review provides an overview of nicotine dependence measures used with perinatal women and an evaluation of their psychometric properties. Fifty-five articles that met inclusion and exclusion criteria were identified from five different databases. Most of the studies used the Fagerström Test for Nicotine Dependence (FTND).

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Effects of glucan on bone marrow.

Ann Transl Med

February 2014

1 Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic ; 2 University of Louisville, Department of Pathology, Louisville, KY, USA.

Bone marrow damage represents a significant problem in cancer treatment. Therefore, it is clear that the pharmacologic protection against bone marrow damage is of considerable interest, since the development of novel and effective medical approaches to combat radiation or cytotoxic damage are of major importance not only to the medical field but also to several industries and the military. This review represents a summary of our knowledge of the effects of various glucans on bone marrow protection.

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