1 results match your criteria: "1st Department of Pediatrics of Athens University[Affiliation]"
Expression of epidermal growth factor receptor and HER-2 in pediatric embryonal brain tumors.
Pediatr Neurosurg
March 2011
Department of Pathology, 1st Department of Pediatrics of Athens University, Athens, Greece.
Background/aims: Medulloblastomas (MBs), atypical teratoid rhabdoid tumors (AT/RTs) and central nervous system primitive neuroectodermal tumors (PNETs) are aggressive embryonal brain neoplasms in children with overlapping histological features but with different pathogenetic pathways. We set out to evaluate the role of epidermal growth factor receptor (EGFR), HER-2, Ki-67 and p53 in embryonal tumors.
Material And Methods: We retrospectively evaluated 36 children with embryonic tumors (27 MBs, 7 AT/RTs and 2 supratentorial PNETs).