Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children's Oncology Group Bone Tumor Committee Consensus Statement.

Trends in diagnostic biopsy sample collection approaches for primary bone sarcomas have shifted in the past 2 decades. Although open/incisional biopsies used to be the predominant approach to obtain diagnostic material for Ewing sarcoma and osteosarcoma, image-guided core needle biopsies have increased in frequency and are safe for patients. These procedures are less invasive and reduce recovery times but have potential limitations.

Trends in diagnostic prevalence and treatment patterns of male and female ankylosing spondylitis patients in the United States, 2006-2016.

Background: There has been much variation between epidemiological studies that report the prevalence of ankylosing spondylitis (AS). This study aimed to analyze the diagnostic prevalence rates and treatment patterns of male and female AS patients in the United States adult insured population from 2006 to 2016.

Methods: Trends in AS prevalence were calculated for the 11-year period covering January 1, 2006 to December 31, 2016.

Quantification of Economic Impact of Drug Wastage in Oral Oncology Medications: Comparison of 3 Methods Using Palbociclib and Ribociclib in Advanced or Metastatic Breast Cancer.

Background: Discarding unused drugs after dose changes or discontinuation can significantly affect pharmacy budgets. This is especially concerning for expensive oncology agents. However, few economic studies account for drug wastage, providing an inaccurate estimate of a drug's actual economic cost, cost-effectiveness, and value.

Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer: Update of the ASCO Endorsement of the Cancer Care Ontario Guideline.

Purpose: To update the American Society of Clinical Oncology endorsement of the Cancer Care Ontario recommendations on the Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer.

Methods: Two phase III trials-the Trial Assigning Individualized Options for Treatment (TAILORx) in women with hormone receptor-positive, node-negative tumors and the Microarray in Node-Negative and 1 to 3 Positive Lymph Node Disease May Avoid Chemotherapy (MINDACT) trial-provided the evidence for this update.

Updated Recommendations: Shared decision making between clinicians and patients is appropriate for adjuvant systemic therapy for breast cancer.

Treatment of Food Selectivity in a Child with Avoidant/Restrictive Food Intake Disorder Through Parent Teleconsultation.

Avoidant/restrictive food intake disorder (ARFID) is a diagnosis for those who display impaired and distressing eating behaviors and symptoms. Behavioral feeding strategies have been shown to be effective at improving food variety and decrease problematic mealtime behaviors in children and adolescents. This study examined the use of teleconsultation for the implementation of a behavioral feeding intervention to increase food variety with a child with avoidant/restrictive food intake disorder.

Patient reported outcomes - experiences with implementation in a University Health Care setting.

Aim: Patient-reported outcomes (PROs) have traditionally been implemented through a manual process of paper and pencil with little standardization throughout a Healthcare System. Each practice has asked patients specific questions to understand the patient's health as it pertains to their specialty. These data were rarely shared and there has not been a comparison of patient's health across different specialty domains.

Potential Acceptability of a Pediatric Ventilator Management Computer Protocol.

Objectives: To examine issues regarding the granularity (size/scale) and potential acceptability of recommendations in a ventilator management protocol for children with pediatric acute respiratory distress syndrome.

Design: Survey/questionnaire.

Setting: The eight PICUs in the Collaborative Pediatric Critical Care Research Network.

Where There is No EMS: Lay Providers in Emergency Medical Services Care - EMS as a Public Health Priority.

By 2030, road traffic accidents are projected to be the fifth leading cause of death worldwide, with 90% of these deaths occurring in low- and middle-income countries (LMICs). While high-quality, prehospital trauma care is crucial to reduce the number of trauma-related deaths, effective Emergency Medical Systems (EMS) are limited or absent in many LMICs. Although lay providers have long been recognized as the front lines of informal trauma care in countries without formal EMS, few efforts have been made to capitalize on these networks.

Neuropsychological Practice Effects in the Context of Cognitive Decline: Contributions from Learning and Task Novelty.

Although cognitive decline is typically associated with decreasing practice effects (PEs) (presumably due to declining memory), some studies show increased PEs with declines in cognition. One explanation for these inconsistencies is that PEs reflect not only memory, but also rebounds from adapting to task novelty (i.e.

Treatment of skin and soft tissue infections in a pediatric observation unit.

Objectives: To report the success rate of observation unit (OU) treatment of pediatric skin and soft tissue infections (SSTIs) and to see if we could identify variables at the time of initial evaluation that predicted successful OU treatment.

Methods: A retrospective review of children less than 18 years of age admitted for SSTI treatment to our OU from the emergency department between January 2003 and June 2009.

Results: On records review, 853 patients matched eligibility criteria; median age was 5.

Pediatric and neonatal extracorporeal membrane oxygenation: does center volume impact mortality?*.

Objective: Extracorporeal membrane oxygenation, an accepted rescue therapy for refractory cardiopulmonary failure, requires a complex multidisciplinary approach and advanced technology. Little is known about the relationship between a center's case volume and patient mortality. The purpose of this study was to analyze the relationship between hospital extracorporeal membrane oxygenation annual volume and in-hospital mortality and assess if a minimum hospital volume could be recommended.

Nurses as knowledge workers: is there evidence of knowledge in patient handoffs?

Patient care handoffs are critical to ensuring continuity of care and patient safety. Current definitions of handoffs focus on information, but preventing errors and improving quality require knowledge. The objective of this study was to determine whether knowledge and wisdom were exchanged during medical and surgical patient care handoffs and to discover how these were expressed.

Public perception of cancer survival rankings.

Past research has observed that certain subgroups (e.g., individuals who are overweight/obese) have inaccurate estimates of survival rates for particular cancers (e.

Increased OLED radiative efficiency using a directive optical antenna.

We investigate the improvement in efficiency of organic light emitting diodes/displays (OLEDs) by embedding a typical OLED structure within a metallic patch grating resonator. A patch grating resonator is similar to the more familiar Fabry-Perot resonator, except that one mirror of the resonator is a metallic patch grating with a pitch approximately lambda /2 that reduces lateral propagation of radiative emission. FDTD simulations of the proposed structure indicate a potential 71% increase in emitted power over that of a reference OLED structure, and an additional 5% gain from adding an ITO spacer adjacent to the metallic electrode layer (for a total 76% increase).