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Kisspeptin is the peptide product of the KiSS-1 gene and endogenous agonist for the Kiss1 receptor. It is known that kisspeptin, acting centrally, stimulates secretion of gonadoliberin (GnRH). Kisspeptin interacts with other neuropeptides such as neurokinin B and dynorphin, to regulate GnRH pulse generation and also plays a role in sexual behaviour.

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