3 results match your criteria: "1780 East University Avenue[Affiliation]"

Toxin tolerance across landscapes: Ecological exposure not a prerequisite.

Funct Ecol

August 2022

School of Biological Sciences, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA.

Article Synopsis
  • A study assessed the tolerance of two herbivorous woodrat species (desert woodrat and Bryant's woodrat) to creosote bush, a toxic plant, across a 900 km area in the US southwest.
  • Researchers used plant metabarcoding of feces to determine consumption levels and conducted feeding trials to measure tolerance, finding significant differences between the species.
  • Woodrats living close to creosote bush were more tolerant to its toxic resin, suggesting that herbivores can adapt to toxic plant metabolites even when not directly exposed, prompting further investigation into genetic factors behind this tolerance.
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Ionizing radiation (IR) is one of the most widely used treatments for cancer. However, acute damage to the gastrointestinal tract or gastrointestinal acute radiation syndrome (GI-ARS) is a major dose-limiting side effect, and the mechanisms that underlie this remain unclear. Here we use mouse models to explore the relative roles of DNA repair, apoptosis, and cell cycle arrest in radiation response.

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Background: This research offers two exploratory frameworks, one for medical regimen compliance and one for medical immediacy. The first classifies compliance awareness, compliance mitigation, and financial limitation for those patients that exhibit nonadherence with a medical regimen. The second classifies medical immediacy and characterizes avoidable utilization.

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